Senior Research Scientist, Metabolism and Toxicokinetics

Reposted 14 Days Ago
Be an Early Applicant
Newark, DE, USA
In-Office
Senior level
Greentech • Software • Agriculture
The Role
Lead the design, execution, and interpretation of ADME and toxicokinetic studies to support crop protection product discovery and regulation. Provide expertise and technical leadership to teams, communicate findings, and manage projects effectively.
Summary Generated by Built In

Corteva Agriscience™ is seeking an experienced Senior Research Scientist to provide scientific and technical leadership in metabolism and toxicokinetics in support of crop protection product discovery and global regulatory registration. Based at the Haskell R&D Center in Newark, Delaware, this role will lead the design, execution, interpretation, and reporting of in vitro and in vivo ADME and toxicokinetic studies. The successful candidate will serve as a subject matter expert in the support of human health safety assessments of crop protection products.

What you’ll do:

  • Design, interpret, and report results for discovery (non-GLP) and regulatory (GLP) studies in toxicokinetics or ADME (absorption, distribution, metabolism, and excretion) to advance the crop protection chemical discovery and registration pipelines.
  • Provide subject matter expertise for the ADME sciences within the Global Regulatory Sciences function on cross-functional discovery and development project teams.
  • Provide technical leadership and coaching to junior scientific staff.
  • Communicate findings to business and scientific audiences, through both oral presentations and written technical reports and manuscripts.

What skills you need:

  • Ph.D. in pharmacokinetics, toxicology, or related area with at least five years of relevant experience.  Or, BS or MS degree in related discipline with minimum 15 years relevant experience.
  • Demonstrated experience and expertise in the design of in vitro (e.g., hepatocyte/metabolic stability, plasma protein binding) and in vivo (e.g., rodent metabolism and mass balance) ADME studies.
  • Thorough knowledge and expertise in xenobiotic metabolism, clearance mechanisms, absorption, and toxicokinetics.
  • Demonstrated teamwork and leadership abilities to manage and coordinate multiple projects and chemistries in a timely and effective manner.
  • Strong written and oral communication skills that allow dissemination of complex technical issues in a clear, concise manner to a variety of scientific and non-scientific audiences.

What makes you stand out:

  • Experience as a study director working in a GLP (Good Laboratory Practice) environment, preferably in industry or CRO.
  • Experience working safely with radioactivity, including carbon-14.
  • Experience using commercial pharmacokinetic and physiologically based kinetic (PBK) modeling software (e.g. Phoenix® WinNonlin®, GastroPlus®).
  • Track record of impactful publications in ADME, PBK modeling, or toxicology

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Benefits – How We’ll Support You:

  • Numerous development opportunities offered to build your skills

  • Be part of a company with a higher purpose and contribute to making the world a better place

  • Health benefits for you and your family on your first day of employment

  • Four weeks of paid time off and two weeks of well-being pay per year, plus paid holidays

  • Excellent parental leave which includes a minimum of 16 weeks for mother and father

  • Future planning with our competitive retirement savings plan and tuition reimbursement program

  • Learn more about our total rewards package here - Corteva Benefits

  • Check out life at Corteva! www.linkedin.com/company/corteva/life


Are you a good match? Apply today! We seek applicants from all backgrounds to ensure we get the best, most creative talent on our team.

Corteva Agriscience is an equal opportunity employer. We are committed to embracing our differences to enrich lives, advance innovation, and boost company performance. Qualified applicants will be considered without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, military or veteran status, pregnancy related conditions (including pregnancy, childbirth, or related medical conditions), disability or any other protected status in accordance with federal, state, or local laws.

Skills Required

  • Ph.D. in pharmacokinetics, toxicology, or related area with at least five years of relevant experience
  • BS or MS degree in related discipline with minimum 15 years relevant experience
  • Experience in design of in vitro and in vivo ADME studies
  • Expertise in xenobiotic metabolism, clearance mechanisms, absorption, and toxicokinetics
  • Strong written and oral communication skills
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The Company
HQ: Indianapolis, IN
17,000 Employees
Year Founded: 2020

What We Do

Corteva Agriscience combines industry-leading innovations, high-touch customer engagement and operational execution to profitably deliver solutions for the world's most pressing agriculture challenges. Corteva generates advantaged market preference through its unique distribution strategy, together with its balanced and globally diverse mix of seed, crop protection, and digital products and services. With some of the most recognized brands in agriculture and a technology pipeline well positioned to drive growth, the company is committed to maximizing productivity for farmers, while working with stakeholders throughout the food system as it fulfills its promise to enrich the lives of those who produce and those who consume, ensuring progress for generations to come.

Why Work With Us

Corteva Agriscience is the only major agriscience company in the world completely dedicated to agriculture. Our purpose is to enrich the lives of those who produce and those who consume, ensuring progress for generation to come.

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