Senior Research Associate, Process Development

Position Summary

We are looking for a motivated, data-driven researcher to join our Process Development (PD) team as a Senior Research Associate. You have a knowledge of basic immunology principles, bioprocess development, and cGMP manufacturing. You should also have experience in primary cell culture (T cells preferred), in different formats including flasks and bags. You will help develop a clinical manufacturing process of engineered T cells with patient-derived neo-antigen specific TCRs. You will also be part of a team involved in implementing technology and participating in technology transfer to the clinical setting.

Responsibilities

• Implement process development studies to develop, scale-up and transfer cGMP manufacturing processes.
• Perform cell culture of T cells in multiple formats including flasks, bags, and bioreactors.
• Collaborate within the project team to interpret study results and contribute to technical discussions for subsequent study design.
• Prepare experimental proposals, technical reports, SOPs and manufacturing batch records.
• Work collaboratively within PD group and with other groups to meet Tech Ops organization goals.
• Other responsibilities as assigned.

Education and Experience

• MS degree in Immunology, Cell Biology, Molecular biology, Bioengineering, or relevant degrees with 1+ years relevant industry experience or BS degree with 2+ years relevant industry experience.
• Experience in technical development of cell and gene therapy or biologics in early and late development setting.
• Hands-on experience in cell and gene therapy, specifically in T cells.
• Experience in Flow Cytometry.
• Knowledge of cGMP manufacturing and regulations and practical experience in GMP operations.
• Knowledge of on board diagnostics (ObD) , design of experiments (DOE) and appropriate statistical analysis for process development.

When we put unexpected teams in the same room, we fuel bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base salary for this position ranges from $87,200 to $109,000. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related experience. If hired, employee will be in an "at-will position" and we reserve the right to modify base salary (and any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Benefits

• Short-term incentive bonus opportunity
• Equity-based long-term incentive program
• 401(k) plan
• Paid vacation and holidays; paid leaves
• Health benefits including medical, prescription drug, dental, and vision coverage.