Senior Research Associate I- Protein Therapeutics

Posted 18 Days Ago
Be an Early Applicant
Foster City, CA
93K-120K Annually
1-3 Years Experience
Biotech
The Role
The Senior Research Associate I will support small and large-molecule drug discovery by planning and conducting protein production experiments, performing protein expression and purification, troubleshooting challenges, and communicating results with project teams.
Summary Generated by Built In

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
 

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description
 

Gilead Sciences Research has a new opportunity for a motivated Research Associate to join our Protein Biochemistry team. Our goal is to develop, build, produce, purify, and validate target proteins to support small and large-molecule drug discovery projects covering a variety of therapeutic areas including inflammation, oncology, and virology.

We are looking for a candidate who will play a critical and independent role in our team. This individual will be responsible for planning and conducting protein production experiments to facilitate R&D activities and project objectives. With guidance, the candidate will assist other functions and teams by performing routine experiments such as preparing recombinant proteins for biochemical assays, structure determination, and in vivo studies. We are seeking a confident, proactive, and dedicated individual with proven experience in protein sciences, who is eager to learn new skills and fully understands the impact of their contributions to our success.

Key Responsibilities:

  • Perform protein expression, purification and QC characterizations of recombinant proteins to support drug development in multiple therapeutic areas
  • Proactively troubleshoot purification challenges and develop purification process and strategies
  • Excellent oral and written communication.  Good understanding of scientific data and update project teams of protein status.
  • Actively participate in group meetings, present the results, interpret data, and draw conclusions regarding presented material.
  • Maintain awareness of cutting-edge technical developments and scientific knowledge and apply these where possible to improve process efficiency.

Qualifications:

  • Strong background in protein sciences and protein biochemistry
  • BS degree with 2+ years in related scientific discipline or MS degree in related scientific discipline with no industry experience. Preferred experience: BS with 4+years and MS with 2+years direct experience in expression and purification of a variety of recombinant proteins
  • Extensive hands-on experience in purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using AKTA FPLC system.
  • Proficiency with various analytical protein characterization techniques such as SEC-HPLC, Western blot, SDS-PAGE, Endosafe
  • Ability to multi-task and excel in a fast-paced team environment
  • Attention to detail, accurate record keeping, and good lab citizenship practices are essential

Other preferred skills:

  • Good understanding of gene cloning and construct design
  • Experience with protein expression using E. coli, insect and mammalian expression systems is desired
  • Experience with other protein characterization technologies (DLS, SEC-MALS, LC/MS, Mass Photometry) would be a strong plus
  • Familiar with structure-based design and engineering of proteins (sequence alignment, protein structure analysis using modeling software) is ideal.


 

The salary range for this position is: $92,820.00 - $120,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.


For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact [email protected] for assistance.
 

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

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PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.


For Current Gilead Employees and Contractors:

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Top Skills

Protein Biochemistry
The Company
HQ: Foster City, CA
14,337 Employees
On-site Workplace
Year Founded: 1987

What We Do

The way we see it, the impossible is not impossible. It’s simply what hasn’t been achieved yet. For more than 30 years, we’ve pursued it, chased it down, tackled it for answers and surrounded it for a way in. We have worked tirelessly to bring forward medicines for life-threatening diseases.

Creating Possible drives everything we do. It’s evident in our mission and core values. This is how we built a culture of excellence that is fueled by a passion for improving lives of people around the world.

For us, nothing is impossible – because of the people we work with, the communities we stand with and the partners we push forward with. Our ~12,000 employees band together through science, grit, compassion and courage to prove the impossible wrong.

At Gilead, the tangible results of your contributions are evident. Where every individual matters. Where all employees can enhance their skills through ongoing development. And where we start every day with one question: “What’s next?”

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