Senti Bio is seeking a highly motivated and experienced individual with experience in Analytical Development. The successful candidate will contribute to the advancement of Senti’s proprietary immunotherapeutic cell engineering platforms focused on genetically modified cellular therapies. The role will support the development of cell-based functional assays and the characterization of processes and products by flow cytometry. The successful candidate will support the new method development, which may include qualification activities, and will also collaborate across Tech Ops during the developmental/optimization phases in manufacturing the product. We are looking for someone with a technically strong background with flow cytometry assays and/or cell-based assays and strong cell culturing experience of adherent and suspension cells looking to build on their Analytical Development experience.
Responsibilities
- Learn and execute Senti’s platform assays to support process development.
- Support assay development for various platform technologies
- Provide testing support for Tech Ops and Research and Development as needed
- Collaborate and work closely with various teams
- Write Test Methods and SOPs
- Independently perform experiments, organize, analyze, and report results
- Successfully execute and document laboratory procedures and experiments with great attention to detail in electronic lab notebooks
Qualifications
- Bachelor’s degree in Cell Biology or related life science field.
- 4+ years of relevant experience, analytical development industry experience is strongly preferred.
- Strong technical independence in cell culture and flow cytometry with some experience in cell-based assays
- Strong experience with Flow Jo or similar flow cytometry data analysis software
- Experience with cell therapy is a plus
- Experience working in a QC/GMP environment is a plus
- Ability to multitask and meet deadlines in a fast-paced environment
- Ability to think critically and demonstrate troubleshooting and problem-solving skills
- Team player, proactive and willing to work in a small team environment
- Excellent verbal and written communication skills
- Proficient with MS office and other commonly used software and technology platforms
- Self-motivated and eager to take on temporary responsibilities outside of the initial job description to support the team
Salary and Benefits
- Compensation for this role includes hourly base salary
- The base hourly range for this role is $46.00-$55.00. Starting pay is determined by multiple job-related factors including a candidate’s skills, education and experience level, benchmark, and internal parity.
- Significant growth opportunity as the company expands.
- Empathetic, supportive, and collaborative colleagues and work environments
Skills Required
- Bachelor's degree in Cell Biology or related life science field
- 4+ years of relevant experience
- Strong technical independence in cell culture and flow cytometry
- Experience with Flow Jo or similar software
- Experience working in a QC/GMP environment
- Strong communication skills
- Proficient with MS office and other software
What We Do
Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable. To accomplish this mission, we are building a synthetic biology platform that could enable us to program next-generation cell and gene therapies with what we refer to as “gene circuits”. These gene circuits, which are created from novel and proprietary combinations of DNA sequences, are intended to reprogram cells with biological logic to sense inputs, compute decisions and respond to their cellular environments. We are designing gene circuits to improve the “intelligence” of cell and gene therapies in order to enhance their therapeutic effectiveness against a broad range of diseases that conventional medicines do not readily address. For more information, please visit the Senti Bio website at https://www.sentibio.com.
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