Senior Research Associate, Discovery Pharmacology

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8 Locations
In-Office or Remote
109K-140K Annually
Senior level
Biotech
The Role
Supports drug discovery and development projects through mammalian cell culture, biological and bioanalytical assay design, optimization, automation, execution, and troubleshooting. Develops SOPs, documents experimental data in ELNs, analyzes results, and presents findings to project teams. The role focuses on AAV gene therapy assays, genome titration, transgene expression, protein analysis, and advanced assay technologies, with approximately 80% of time devoted to benchtop science.
Summary Generated by Built In
Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at altoslabs.com.

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list.  At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

What You Will Contribute To Altos

At Altos, your work will be at the heart of our mission to transform medicine by reversing disease and restoring cellular health. You will help develop a new generation of therapeutics rooted in an advanced understanding of cellular rejuvenation and resilience. 

We are currently seeking a highly capable and motivated Senior Research Associate to join our Discovery Pharmacology team. In this role, your primary focus will be supporting critical drug discovery and development projects by executing a wide range of biological and bioanalytical assays. We are looking for a dedicated team player who values collaborative success and open communication. Your expertise will directly advance our drug discovery campaigns across a diverse portfolio, making a significant impact on aging biology, rejuvenation, and the future of medicine.

Responsibilities

  • Work both independently and collaboratively with the scientific manager to drive drug discovery and development projects.
  • Culture and maintain mammalian cells, manage reagents and working stocks in addition to contributing to general lab maintenance.
  • Design, optimize, automate, execute, and troubleshoot a range of assays, including cellular, biochemical, and complex in vitro bioassays.
  • Standardize and optimize assay protocols and draft assay SOPs. 
  • Document assay methods, raw data, and results in an electronic laboratory notebook (ELN), ensuring reproducibility and data integrity.
  • Make presentations and present data at project team meetings to support decision making. 
  • The responsibilities of this role are expected to require ~80% of time dedicated to benchtop science.
Who You Are 

Required Qualifications

  • BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related discipline, and a minimum of 5 years of industry experience in a drug discovery and/or development setting.
  • Strong expertise in technical methods in AAV gene therapy for cellular transduction assays (aseptic technique), genome titration (qPCR, ddPCR), transgene expression (RT-qPCR, ddPCR), and protein analysis (Western Blot, ELISA, and capillary electrophoresis). 
  • Good understanding and hands-on experience developing and performing a wide range of analytical and bioassays with fluency in data analysis and application of statistical modalities. 
  • Experience in state-of-art assay technologies such as MSD, HTRF, AlphaLISA, Luminex, etc.
  • Hands on experience in automation instruments and platforms (e.g. Bravo, Echo, I.DOT, Digital dispenser, etc.). 
  • Proficient in documenting experimental design, analysis and interpretation of data in ELN.
  • Excellent data presentation, oral and written communication skills. 
  • Detail-oriented, organized, flexible, and capable of multitasking in a fast-paced environment. 

Preferred Qualifications

  • Experience working across diverse therapeutic modalities, including viral based gene therapy, mRNA-LNP or other nucleic acid therapeutics, and small molecules.
  • Background in the field of aging/rejuvenation biology.
  • Familiarity with assay qualification criteria, processes, and SOP authoring.

The salary range for Redwood City:

  • Senior Research Associate: $109,200 - $140,000

Exact compensation may vary based on skills, experience, and location.

#LI-NN1

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

Equal Opportunity Employment

We value collaboration and scientific excellence.

We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment.

Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/

Skills Required

  • BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related discipline
  • Minimum of 5 years of industry experience in a drug discovery and/or development setting
  • Expertise in AAV gene therapy cellular transduction assays using aseptic technique
  • Experience with genome titration using qPCR and ddPCR
  • Experience measuring transgene expression using RT-qPCR and ddPCR
  • Experience with protein analysis using Western blot, ELISA, and capillary electrophoresis
  • Hands-on experience developing and performing analytical and bioassays
  • Fluency in data analysis and statistical methods
  • Experience with MSD, HTRF, AlphaLISA, Luminex, or similar assay technologies
  • Hands-on experience with automation instruments and platforms such as Bravo, Echo, I.DOT, and digital dispensers
  • Proficiency documenting experimental design, analysis, and interpretation in an ELN
  • Excellent data presentation, oral communication, and written communication skills
  • Experience with viral gene therapy, mRNA-LNP, other nucleic acid therapeutics, or small molecules
  • Background in aging or rejuvenation biology
  • Familiarity with assay qualification criteria, processes, and SOP authoring

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The Company
HQ: Redwood City, California
280 Employees

What We Do

Altos Labs™ is a biotechnology company focused on cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine. The company comprises a community of leading scientists, clinicians, and leaders from both academia and industry working together towards this common mission. Altos has operations in the San Francisco Bay Area and San Diego, and in Cambridge, UK, with significant collaborations in Japan. Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos.

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