Senior Research Associate, Biology

Posted 10 Days Ago
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Cambridge, MA
Junior
Biotech
The Role
In this role, the Senior Research Associate will execute cell and molecular biology activities, develop and validate functional cell-based assays, and collaborate with colleagues to advance drug discovery campaigns focused on transcription factors.
Summary Generated by Built In

Flare Therapeutics is a biotechnology company pioneering a new therapeutic space with a novel approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of its scientific founders, Flare’s team has uncovered ‘switch sites,’ druggable regions that are key targets for transcription factor regulation, to address mutations that cause disease. Flare’s drug discovery efforts to target switch sites has rapidly advanced, resulting in an emerging pipeline of research programs that address well-validated genetically defined transcription factors, initially focused on precision oncology.


We are a collective of brilliant fires, trailblazing a path to conquer transcription factors and create cutting-edge medicines for patients. We embrace diversity in all its forms, experiences, and viewpoints. We are inspired by the unknown and willing to take risks. We are passionate about the science we pursue and compassionate about the patients it stands to benefit. And we respect, value, and believe in each other.


In this role you will...

  • As a member of the Biology team, execute on cell and molecular biology activities across Flare’s pipeline and early discovery projects 
  • Develop, validate and perform a variety of functional cell-based assays to drive drug discovery campaigns 
  • Collaborate with chemistry, biochemistry, and translational colleagues to interrogate the mechanism of action of small molecule modulators of transcription factors to improve compound efficacy for H2L and LO advancement
  • Present data and research plans to the teams to inform data-driven decisions 

About you…

  • You have a BS or MS in molecular or cellular biology, or related field 
  • You have at least 2 years (MS) or 4 years (BS) of experience in biotech/pharma
  • You have experience with cell assay development, drug discovery screening, and mechanistic studies
  • You are experienced in cell engineering (shRNA, CRISPR knockin/knockout, generation of stable lines, viral transduction, etc.)
  • You have worked in oncology and/or transcriptional regulation 
  • You have an aptitude to work with drug discovery databases
  • You consider yourself to be a self-starter with a great ability to prioritize and balance multiple tasks and meet multiple deadlines
  • You thrive in a dynamically changing and fast-paced environment, are very team oriented and comfortable with changing priorities
  • You have strong communication skills, both written and verbal, including presenting data to the internal company meetings
  • You have a strong passion for science and are driven by making a meaningful contribution for patients
  • You love the lab!
  • You get along equally well with people, cultured cells, and multi-well plate readers

Flare Therapeutics is proud to foster a diverse, equitable and inclusive company culture that embraces all people that are essential to who we are, what we do and what we believe. Flare Therapeutics is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.



 

TO ALL AGENCIES: Please, no phone calls or emails to any employee of Flare Therapeutics about our openings. All resumes submitted by search firms/employment agencies to any employee at Flare Therapeutics via email, the internet or in any form and/or method will be deemed the sole property of Flare Therapeutics, unless such search firms/employment agencies were engaged by Flare Therapeutics for this position and a valid agreement with Flare Therapeutics is in place. In the event a candidate who was submitted outside of the Flare Therapeutics agency engagement process is hired, no fee or payment of any kind will be paid.

Top Skills

Cell
Crispr
Molecular
Shrna
The Company
HQ: Cambridge , MA
41 Employees
On-site Workplace
Year Founded: 2021

What We Do

Our team ‘brings it’ every day for one mission: to conquer transcription factors and create cutting-edge medicines for patients.

Flare is lighting up a new therapeutic space with an entirely different approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of our scientific founders, Flare’s team is leveraging the power of ‘switch sites’ as druggable regions that hold the control for predictable and profound changes in DNA transcription, and therefore, gene expression. Our drug discovery to target ‘switch sites’ has rapidly advanced, resulting in our pipeline of drug programs that address well-validated transcription factors, initially focused on precision oncology.

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