Senior Project Manager - Life Sciences

Reposted Yesterday
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St Louis, MO, USA
In-Office
Senior level
Professional Services • Real Estate • Design
The Role
Lead design-build life sciences construction projects from concept through closeout for $60M–$250M developments. Manage budgets, schedules, buyouts, subcontractors, safety, and project teams while mentoring staff and coordinating architects, engineers, and planners.
Summary Generated by Built In

About Us

Clayco is a full-service, turnkey real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across North America the highest quality solutions on time, on budget, and above and beyond expectations. With $8.1 billion in revenue for 2025, Clayco specializes in the "art and science of building," providing fast track, efficient solutions for mission critical, industrial, life sciences, power & energy, aviation, commercial, institutional, residential and sports & entertainment related building projects.

The Role We Want You For

The Senior Project Manager will be based on the construction project site and will be responsible for taking projects from conceptual stages through closeout. Provide leadership, technical direction, and deliver the best solutions on design-build projects within the dynamic Life Sciences/Biotech/Pharmaceuticals sector valued anywhere from a $60 million to over $250 million. At Clayco, a Senior Project Manager is responsible for assisting with preconstruction, buying out contracts, and managing the project from start to finish.

The Specifics of the Role

  • Build client and subcontractor relationships.
  • Team with Architects, Engineers, and Planners to create and manage a design schedule.
  • Establish project forecasts and budgets.
  • Manage costs.
  • Accept full responsibility for project execution.
  • Mentor and develop project management staff.

Requirements

  • Bachelor’s Degree in Construction Management, Engineering, Architecture or related.
  • 10-15 years of experience managing construction projects ($50+ million) ideally design-build.
  • Strong project safety record and commitment to safety and quality.
  • Previous experience with set-up, budget planning, buyout, and cost reporting.
  • Demonstrated knowledge of construction principles, practices, and technology.
  • Previous experience leading a successful project management team.
  • Creative and results-oriented with a sense of urgency.
  • Ability to walk the job site, climb ladders, and multi floor scaffolding.
  • Ability to lift objects at least 50lbs.

Some Things You Should Know

  • This position is based in St. Louis, MO.
  • Our clients and projects are nationwide – Travel will be required.
  • No other builder can offer the collaborative design-build approach that Clayco does.
  • We work on creative, complex, award-winning, high-profile jobs.
  • The pace is fast!
  • This position is classified as a safety-sensitive role in accordance with applicable state and federal laws. Candidates selected for this position will be subject to a comprehensive background check, which includes mandatory drug testing.

Why Clayco?

  • 2025 Best Places to Work – St. Louis Business Journal, Los Angeles Business Journal, and Phoenix Business Journal.
  • 2025 ENR Top 400 – Top Data Center Contractor (Top 3).
  • 2025 ENR Top 100 Design-Build Firms – Design-Build Contractor (Top 5).
  • 2025 ENR Top 100 Green Contractors – Green Contractor (Top 3).

Benefits

  • Discretionary Annual Bonus: Subject to company and individual performance.
  • Comprehensive Benefits Package Including: Medical, dental and vision plans, 401k, generous PTO and paid company holidays, employee assistance program, flexible spending accounts, life insurance, disability coverage, learning & development programs and more!

Compensation

  • The salary range for this position considers a wide range of factors in making compensation decisions including but not limited to: Education, qualifications, skills, training, experience, certifications, internal equity, and location. Compensation decisions are dependent on the facts and circumstances of each case.


Skills Required

  • Bachelor's Degree in Construction Management, Engineering, Architecture or related
  • 10-15 years managing construction projects of $50+ million, ideally design-build
  • Strong project safety record and commitment to safety and quality
  • Experience with project setup, budget planning, buyout, and cost reporting
  • Demonstrated knowledge of construction principles, practices, and technology
  • Previous experience leading a successful project management team
  • Ability to walk job site, climb ladders and multi-floor scaffolding
  • Ability to lift objects at least 50 lbs
  • Creative, results-oriented with a sense of urgency

Clayco Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Clayco and has not been reviewed or approved by Clayco.

  • Fair & Transparent Compensation — Pay is considered competitive versus industry peers, with many noting strong base salaries and perceived fairness across key roles. Feedback suggests compensation often feels adequate even amid demanding project environments.
  • Strong & Reliable Incentives — Bonuses are described as structured and performance-based, contributing meaningfully to total compensation. Feedback suggests these incentives help offset the intensity and travel demands of project work.
  • Retirement Support — Retirement benefits are viewed as strong due to a 401(k) with company match and profit-sharing options. Public disclosures portray employer contributions as robust, reinforcing long-term financial security.

Clayco Insights

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The Company
HQ: Chicago, IL
4,000 Employees
Year Founded: 1984

What We Do

Clayco is a full-service, turnkey firm providing real estate, architecture, engineering, design-build and construction services across North America. The company delivers integrated project solutions intended to meet clients’ quality, schedule and budget expectations. Its work emphasizes collaborative design, construction quality, craftsmanship, efficient project management, cost containment and jobsite safety, making it one of the nation’s largest privately owned firms.

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