We are seeking an experienced, driven, and collaborative Director of Program Management to lead the execution of complex, cross-functional client programs in the development and GMP manufacturing of cell and gene therapies. This leader will be responsible for driving program success across multiple client engagements and ensuring alignment with strategic and operational goals.
This role requires deep understanding of GMP operations, program and stakeholder management, and the ability to lead both internal teams and external clients with clarity, confidence, and accountability.
Responsibilities
- Lead and oversee multiple complex, cross-functional client programs from contract award through closure, ensuring on-time, on-budget, and on-scope delivery.
- Own the client relationship for assigned programs; serve as the main point of contact and ensure program health, transparency, and trust with both internal and external stakeholders.
- Develop and maintain program documentation, including charters, timelines, risk registers, change orders, budgets, meeting minutes, and stakeholder reports.
- Drive strategic alignment between program objectives and broader business goals; contribute to long-term planning, client development, and organizational strategy.
- Collaborate cross-functionally with Process & Analytical Development, Quality, GMP Manufacturing, Supply Chain, Facilities, Engineering, Quality Control and Regulatory to deliver program milestones.
- Identify and manage program risks through proactive mitigation planning and structured risk management frameworks.
- Track and report on key performance indicators (KPIs), such as delivery timelines, client satisfaction, quality metrics, and budget adherence.
- Lead program steering committees and governance forums; prepare executive-level presentations and reports for internal and client leadership.
- Contribute to the development of scalable PMO tools and frameworks, including Smartsheet dashboards, process maps, and templates.
- Champion process improvements, lead root-cause analyses for program deviations, and contribute to organizational learning and maturity.
Qualifications
- BA/BS degree in a relevant field required; advanced degree (MS, MBA, PhD) is a plus.
- 10+ years of program or project management experience in life sciences, with at least 5 years leading cross-functional programs in GMP manufacturing of cell, gene, or biologic therapies.
- Proven ability to lead client-facing engagements, manage complex stakeholders, and resolve cross-functional conflicts.
- 3+ years of people management experience, including direct reports and matrixed team leadership preferred.
- Deep understanding of GMP principles and regulated development environments.
- PMP certification or equivalent is preferred.
- Strong knowledge of project management tools and systems, including Smartsheet, Microsoft Project, and PowerPoint.
- Demonstrated financial acumen, including budget tracking and change order management.
- Experience working in a matrixed, fast-paced, and early-stage environment is a plus.
- Strategic thinker with excellent execution discipline
- Exceptional communicator and relationship builder
- High emotional intelligence and leadership presence
- Comfortable with ambiguity, change, and problem-solving
- Passionate about improving human health through scientific innovation
Ideal Candidate Attributes:
Landmark Bio is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.
Skills Required
- BS degree with 7+ years relevant experience in GMP pharmaceutical, biologics, and/or cell and gene therapy field
- PMP certification
- Proficiency in Smartsheet with advanced skills
- Strong communication, problem solving, planning, and project management skills
- Ability to support more than one project of a reasonable size simultaneously
What We Do
Landmark Bio is a collective endeavor launched by leaders from academia, the life sciences industry, and world-renowned research hospitals to accelerate development and industrialization of next-generation genomic medicine. Inspired by recent advancements in cell and gene therapy, Landmark Bio was established to remove barriers in drug development, create accessible capability, expertise, and solutions, and offer a collaboration platform to advance manufacturing technologies for the new generation of medicines to come. Founding partners include Harvard University, Massachusetts Institute of Technology (MIT), Cytiva, FUJIFILM Diosynth Biotechnologies (FDB), and Alexandria Real Estate Equities, Inc. Other collaborating institutions include Beth Israel Deaconess Medical Center, Boston Children’s Hospital, Mass General Brigham, and the Dana-Farber Cancer Institute. For more information please contact [email protected]
Why Work With Us
Landmark Bio was conceived to accelerate life sciences innovation. Our cross-sector network, expert staff and consultants, state-of-the-art facility, and broad definition of how a true partner can expedite translational research make us unique. Our mission Is to translate groundbreaking research into life-changing therapies.
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