Oxford Nanopore Technologies: Our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere.
The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis.
The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins.
The technology is used to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments.
With a thriving culture of ambition and strong innovation goals, Oxford Nanopore is a UK headquartered company with global operations and customers in more than 125 countries.
We are seeking a highly capable Senior PCB Design Engineer to own the design and delivery of complex, mixed-signal and RF printed circuit boards from initial requirements through to production.
About the Role
Are you a hands-on hardware specialist who enjoys taking complex ideas from concept to production?
We are looking for a skilled Senior PCB Design Engineer to own the entire hardware lifecycle for our next generation of products.
In this role, you won't just route boards—you will architect, simulate, and validate complex mixed-signal, digital, analogue, and RF assemblies. Operating as a critical link between hardware architecture and physical manufacturing, you will use Altium Designer to deliver robust, high-performance designs that succeed on the first spin.
Key Responsibilities….
You will own the end-to-end design cycle, driving excellence across the following stages:
- Translate high-level system requirements into robust architectures, component selections, schematic captures, and complete PCB layouts.
- Apply industry-best practices for high-speed design, signal/power integrity, grounding, stack-up definition, thermal management, and EMC/EMI performance.
- Lead hands-on prototype assembly, laboratory debugging, fault-finding, rework, and full design verification.
- Build with production in mind by embedding Design for Manufacture (DFM) and Design for Test (DFT) principles into every layer.
- Manage libraries, support component selection, navigate obsolescence, and collaborate directly with external fabrication and assembly partners.
- Engage with internal engineering, procurement, and quality teams, while maintaining pristine technical documentation and production release records.
- Contribute to continuous process improvements and provide technical guidance and mentoring to less experienced engineers.
What we’re looking for…
- Deep, demonstrable expertise using Altium Designer for schematic capture, complex multi-layer PCB layout, library management, and manufacturing output documentation.
- A proven track record designing complex mixed-signal, high-speed digital, precision analogue, and RF hardware assemblies.
- Experience taking electronic products completely through the design cycle, from a blank page to a scaled production release.
- Strong laboratory debugging and fault-finding capabilities using standard test equipment (oscilloscopes, spectrum analysers, etc.), alongside practical rework skills.
- A strong understanding of component lifecycles, supply chain risk management, and direct vendor liaison.
- Excellent interpersonal skills to collaborate with multi-disciplinary stakeholders and confidently mentor less experienced team members.
If you are ready to own impactful hardware designs and elevate our PCB engineering standards, we want to hear from you.
We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.
If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today!
Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.
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About UsOxford Nanopore Technologies: Our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis. The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins. The technology is used to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments. With a thriving culture of ambition and strong innovation goals, Oxford Nanopore is a UK headquartered company with global operations and customers in more than 125 countries.
Skills Required
- Deep expertise using Altium Designer for schematic capture, complex multilayer PCB layout, library management, and manufacturing documentation
- Experience designing complex mixed-signal, high-speed digital, precision analogue, and RF hardware assemblies
- Experience taking electronic products through the complete design cycle from concept to scaled production release
- Strong laboratory debugging and fault-finding skills using oscilloscopes, spectrum analysers, and other standard test equipment
- Practical electronic hardware rework skills
- Understanding of component lifecycles, supply chain risk management, and vendor liaison
- Excellent interpersonal and collaboration skills with multidisciplinary stakeholders
- Ability to mentor less experienced engineers
Oxford Nanopore Technologies Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Oxford Nanopore Technologies and has not been reviewed or approved by Oxford Nanopore Technologies.
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Fair & Transparent Compensation — Pay is considered good to above average across many roles, with employer-provided ranges visible for several U.S. commercial and applications positions and company materials emphasizing market‑competitive base pay. Commercial and some senior technical posts, particularly in the U.S., are positioned as competitive and often paired with strong variable components.
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Equity Value & Accessibility — All‑employee share plans in the UK and a U.S. employee stock purchase plan indicate broad access to equity as part of total reward. Company communications highlight attractive bonus and share plans that add meaningful upside beyond base pay.
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Healthcare Strength — U.S. roles indicate strong health insurance and core protections, while official materials and country overviews reference private medical coverage and wellbeing support. These elements position the health package as a notable strength alongside cash compensation.
Oxford Nanopore Technologies Insights
What We Do
Our goal is to enable the analysis of anything, anywhere, by anyone. We have developed the world’s first and only nanopore DNA and RNA sequencing platform. It’s a new generation of sequencing technology — the only one to offer: scalability to portable or ultra-high throughput formats, real-time data delivery, and the ability to elucidate rich biological data. We are aiming to disrupt the way that biological analyses are currently performed, and open up new applications that have a profound, positive impact on society. Our devices offer real-time analysis, for rapid insights, in fully scalable formats — from pocket to population scale — and the technology is being used in more than 100 countries worldwide. Founded in 2005 as a spin-out from the University of Oxford, the company now employs more than 600 people from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.


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