The Role
Designs and integrates novel electromechanical and fluidic hardware for GutLab products. Responsibilities include prototype assembly, testing, troubleshooting, repair, test automation, fixture development, documentation, and quality support. The role requires hands-on hardware development, CAD-based design, wiring, soldering, scripting, and collaboration across disciplines to transition products from prototype toward production.
Summary Generated by Built In
Senior Mechanical Engineer
Compensation: $100k – $125k salary + 0.1%– 0.2% equity + benefits
Full benefits, including health coverage, PTO & parental leave
About BiomeSense
BiomeSense is a life sciences startup applying gut microbiome technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.
Key Responsibilities
You will own key technical workstreams responsible for the success of our next-generation GutLab hardware, while providing hands-on support.
Compensation: $100k – $125k salary + 0.1%– 0.2% equity + benefits
Full benefits, including health coverage, PTO & parental leave
About BiomeSense
BiomeSense is a life sciences startup applying gut microbiome technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.
Key Responsibilities
You will own key technical workstreams responsible for the success of our next-generation GutLab hardware, while providing hands-on support.
- Mechanical Design of Novel Hardware: Devise elegant solutions to complex mechanical design problems, balancing performance, risk, and timelines
- Systems Integration: Integrate mechanical, electrical, and fluidic systems into robust products; resolve system-level tradeoffs
- Hardware Build & Test: Perform detailed electrical, mechanical, and fluidic assembly of prototypes and sub-assemblies; lead hands-on validation of new designs
- Troubleshooting & Repair: Diagnose and repair complex hardware, software, and firmware issues in lab and field; identify root causes and drive fixes
- Testing & Automation: Design and improve test setups, fixtures, and automation to optimize assembly and validate hardware; maintain a clean, organized, inventoried hardware lab
- Documentation & Quality: Create clear SOPs, manuals, test records, and design documentation for repeatable production; flag risks and assembly feedback early
- Bachelor’s Degree in Engineering or related field and 5+ years in hardware development
- Experience independently designing complex, novel hardware and test fixtures using CAD
- Proven ability and willingness to perform precise, hands-on assembly and testing of complex electromechanical hardware
- Experience with prototyping techniques (e.g., 3D printing, light machining)
- Proven ability to perform detailed wiring, harnessing, and soldering
- Highly organized, proactive, and independent; owns ambiguous work through resolution and collaborates across disciplines
- Experience with instrument control software and scripting; able to interpret test results and translate findings into design improvements
- Experience taking a new product from prototype to production
- Expertise in Design for Assembly (DFA) and Design for Manufacturing
Skills Required
- Bachelor’s degree in engineering or a related field
- 5+ years of experience in hardware development
- Independent design of complex, novel hardware and test fixtures using CAD
- Hands-on assembly and testing of complex electromechanical hardware
- Experience with prototyping techniques such as 3D printing and light machining
- Detailed wiring, harnessing, and soldering experience
- Highly organized, proactive, and independent work style with cross-disciplinary collaboration
- Experience with instrument control software and scripting
- Ability to interpret test results and translate findings into design improvements
- Experience taking a new product from prototype to production
- Expertise in Design for Assembly and Design for Manufacturing
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The Company
What We Do
BiomeSense is a biotechnology company developing an integrated biosensor and AI-powered platform to massively scale the collection and analysis of gut microbiome data. By leveraging big data and artificial intelligence, the company provides continuous, longitudinal insights into the human microbiome to unlock the full potential of precision medicine and personalized healthcare solutions.







