At Matterworks we are building AI tools to extract insights from the ever-growing corpora of biological data and to unlock opportunities in therapeutic discovery, development, and manufacturing. We are building large-scale deep learning models of biological data to predict the phenotype and behavior of biological systems.
Position Overview
As a Senior Machine Learning Scientist, you will be a core contributor to our deep learning systems, designing, building, and optimizing the neural network architectures that interpret complex mass spectrometry data. You will own significant model components and drive projects from experimentation through deployment. This role requires hands-on depth in deep learning and a passion for building high-quality, impactful models.
Key Responsibilities
Model Development: Design, adapt, and optimize deep learning architectures for our scientific domains and data modalities, working within our Large Spectral Model framework.
Project Execution: Own and deliver on complex ML projects, including experiment design, implementation, evaluation, and iteration based on results.
High iteration velocity: Write clean, well-tested code in PyTorch and NumPy enabling a high experimentation rate.
Research and Innovation: Stay current with deep learning research and its applications in chemistry and biology. Propose and prototype new ideas to enhance our modeling capabilities.
Collaboration: Work closely with scientists and engineers across the team to integrate models into our product and infrastructure.
Qualifications
Ph.D. M.S. in a quantitative field (Computer Science, Chemistry, Physics, or related), or equivalent experience.
3+ years of hands-on experience building and deploying deep learning models.
Strong proficiency in Python, PyTorch, and NumPy.
Demonstrated experience designing or adapting neural network architectures. Publications or a portfolio of relevant projects valued.
Experience with spectral analysis, structure prediction, or molecular representation learning is a plus.
Familiarity with scientific data formats (e.g., HDF5, mzML, Zarr) is a plus.
Given the cross-disciplinary and innovative nature of our work, effective collaboration and communication are critical to our progress. We operate in a flexible hybrid model that accommodates both fully remote team members and those who work full-time from our Somerville, MA office. While some positions may require regular in-person presence for hands-on work or local collaboration, many roles can be performed remotely with team members distributed across various locations.
Compensation and BenefitsMatterworks offers a competitive base salary, stock options, and benefits (health & dental, vision, long- and short-term disability, life insurance, 401k with company match). Employees enjoy a flexible work & unlimited time away policy, commuter benefits and parking, regular team meals and outings, and company support for continued education/coursework and conference participation.
Matterworks, Inc. is an equal opportunity employer. All candidates for employment at Matterworks are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, sexual orientation, or any other category protected by law.
Top Skills
What We Do
Matterworks is developing advanced AI-powered software and proprietary chemistry reagents to enable real-time, quantitative metabolomics to accelerate the research, development, and manufacturing of biologic therapeutics.
Metabolomics measures all the small molecules a cell needs to function. In spite of its far-reaching potential impact across life science disciplines, adoption of metabolomics remains limited and lags behind other ‘omic techniques due to a number of inherent challenges. Matterworks is developing a novel alternative methodology that activates deep learning (DL) for analytical chemistry, to remove the constraints imposed by the requirement for human-interpretable data.
Matterworks is on a mission to democratize metabolomics and catalyze its widespread adoption and integration into the life sciences. Our view is very simple: solving metabolomics will advance all of the life sciences industries.
Why Work With Us
We are a passionate team of scientists and engineers committed to building better tools to interrogate biology and accelerate the rate of scientific progress. In pursuit of our ambitious goals, we rely on our core company values to guide our work: Mission First, Communication & Trust, Growth Through Challenges, and Scientific Excellence.
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