Senior Machine Learning Engineer

Sorry, this job was removed at 12:15 p.m. (CST) on Thursday, Nov 13, 2025
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4 Locations
Remote
Cloud • Database • Analytics • Biotech
The Role

Deep Origin is a biotechnology company accelerating drug discovery through AI-powered tools. Our platforms simplify R&D, simulate biology, and empower scientists to solve diseases and extend healthspan.

We are looking for a Senior ML Engineer with experience in creating predictive models, particularly in the biology space. You will help to create ML-based representations of specific biological systems, as well as take part in tuning and optimization of larger composite models, with the goal of creating a multiscale biological simulator for drug response prediction. You will also work with the Cellular Simulations team to incorporate biological simulations and mechanistic insights into the ML-based approaches.


Requirements
  • B.S. or M.S. in a relevant quantitative field (Computer Science, Math, Physics, etc.).
  • At least 5 years of experience in the development of machine learning models in an industry setting.
  • Knowledge of optimization methodologies for machine learning models.
  • Extensive coding experience, preferably Python, but other language proficiency will be considered depending on experience.
  • Fluent English for collaboration with an international team.

Nice to have:

  • Ph.D. in relevant field.
  • Deep experience in biological modeling and simulation, in particular in a systems biology or molecular level context.
  • Experience with ML tasks involving small datasets.
  • Experience in optimization of “composite models” - connected models that share output/input.
Responsibilities
  • Construct ML-based representations of biological systems, in particular signaling pathway dynamics in cells
  • Help to create a hybrid multiscale biological simulator, incorporating ML components for more effective model calibration and simulation
  • Plan and organize work to ensure specific deadlines and milestones are met, coordinating with others to ensure work is correctly aligned and integrated with other efforts. 
  • Communicate effectively within the company and external teams, updating others frequently on progress and bottlenecks. 

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The Company
HQ: South San Francisco, California
16 Employees
Year Founded: 2022

What We Do

We help scientists solve disease and extend healthspan by building tools that simplify R&D, simulate biology, and untangle the complexity of life. Streamline computational analysis today. Simulate biology tomorrow.

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