Lead Backend (NodeJS) Engineer - Onsite

Sorry, this job was removed at 06:21 p.m. (CST) on Tuesday, Feb 17, 2026
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South San Francisco, CA, USA
In-Office
Cloud • Database • Analytics • Biotech
The Role

About Deep Origin

Led by Michael Antonov, a co-founder of Oculus, and well-funded by Formic Ventures, Deep Origin is poised to reinvent the way scientists work and life science innovations come to life. We see a future largely free of diseases, with a 150-year lifespan being a norm. To get there, we are building an operating system for science, enabling scientists to be more productive and to bring tomorrow's ideas to life quickly and at a reasonable cost.

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

Role Description

In this hands-on position, you will be a key member of the software engineering team, building our key functionality and integrating with key partners. Your responsibilities will range from designing and developing complex, large-scale systems to writing APIs that integrate with various cloud providers and partners. You will have ownership in key software feature areas and their architectural design, as well as software implementation with a high level of independence and impact.


Requirements
  • 7+ years of experience designing, building, and operating complex, highly-scalable, distributed applications and systems
  • 3+ years of hands-on software development experience with TypeScript/JavaScript/NodeJS
  • Experience with both relational databases (e.g. Postgres) and NOSQL (e.g. MongoDB)
  • Knowledge of Kubernetes and Cloud infrastructure/deployment tools (specifically with cluster operations and operators)
  • Has built platforms from an early stage
  • Has scaled platforms to handle many users (10,000+ DAU)
  • Has extensive system-design experience
  • Has experience designing systems with complex data-sets/relations
  • Has experience working with distributed systems/platforms
  • Thinks about architecture first and how the code fits in second
  • Has experience working with/implementing a multi-tenant system
  • Systematic problem-solving approach, coupled with a strong sense of ownership and drive
  • Ability to work both independently and on the team
  • Experience working in high-energy startups with fast product delivery mechanisms

BenefitsBenefits

This position offers a competitive salary, benefits, and equity.

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The Company
HQ: South San Francisco, California
16 Employees
Year Founded: 2022

What We Do

We help scientists solve disease and extend healthspan by building tools that simplify R&D, simulate biology, and untangle the complexity of life. Streamline computational analysis today. Simulate biology tomorrow.

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