Senior Downstream Process Development Scientist

Be part of something altogether life-changing!

Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.

At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly matter with people that care for each other, our customers, and their patients. With associates across 40+ countries, Cytiva is a place where every day is a learning opportunity – so you can grow your career and expand your skills in the long term.

Forming part of the Biotechnology segment at Danaher, we bring together dedicated technical expertise and talent to develop the next generation of life-changing therapeutics.

The Senior Downstream Process Development Scientist for Cytiva is responsible for accelerating discovery, development and delivery of solutions that safeguard and improve human health by collaboration closely with our customers and helping them to improve their downstream processes.

This position is part of the Fast Trak PDVS organization located in Marlborough, MA and will be on-site. At Cytiva, our vision is, to advance future therapeutics from discovery to delivery.

What you will do:

• Fast Trak Senior scientists work as process development leads with the team and directly with our customers in a collaborative environment. You will be leading technical discussions with customers, developing, optimizing and performing downstream processes.

• In this role you will be acting as a project leads as well as conducting independent scientific application work on various projects with monoclonal antibodies, vaccines, recombinant proteins, AAV, Oligonucleotides etc.

• Most PD work is done in process development scale but understanding and experience of large scale biomanufacturing will ensure that scalable solutions are implemented.

• The role also includes learning and delivering training courses for customers as principal instructor, in the field of downstream biomanufacturing.

• You should have in-depth protein purification, resin and filtration knowledge to support and identify successful solutions for our customer’s PD and biomanufacturing processes.

Who you are:

• Expertise in leading downstream technical discussions with customers, developing, optimizing and performing downstream processes, acting as a project leader as well as conducting independent scientific application work on various projects with monoclonal antibodies, vaccines, recombinant proteins, AAV, oligonucleotides etc.

• Bachelor's degree with a minimum of 8 years of experience or MSc or PhD with a minimum of 3-5 years’ experience in biochemistry, biotechnology, bioprocess/biomedical engineering, biochemical/chemical engineering or related life sciences field with experience in DSP PD, scale up, tech transfer, manufacturing or equivalent.

• Extensive hands-on experience and in-depth theoretical knowledge of downstream PD, chromatography techniques (HIC/IEX/SEC/MM/RP/Affinity) and resins, high throughput technologies, protein analytics , scale-up, tech transfer, and/or manufacturing, AKTA systems (Avant /Pure/Pilot 600/Flux S), UNICORN software etc

• Strong analytical experience like Biacore, RP/SEC HPLC(UPLC) coupled with UV/PDA/MALS detectors, CE-SDS, WB, SDS-PAGE, IEF etc

• Hands on experience of column packing techniques/applications like flow packing, axial compression hardware, slurry calculation techniques, pressure/flow diagrams, compression/packing factors, qualification methods (Asymentry, HETP )

Travel, Motor Vehicle Record & Physical/Environment Requirements:

• Ability to travel up to 1-2 times a year for overnight travel, within the East Coast USA

• Ability to lift, move or carry equipment up to 20lb

It would be a plus if you also possess previous experience in:

• Extensive Unicorn text method experience

• Strong experience in different Akta platforms (Akta pure/ Avant /Pilot 600, Akta Ready, Akta Flux S/6)

• Training and mentoring of more junior scientists and able to deliver customer trainings both theoretical and practical as well as identifying and driving update of course content as a subject matter expert.

#LI-KP1

Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. 

For more information, visit www.danaher.com.

Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.

The EEO posters are available here.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at [email protected] to request accommodation.