Senior Director, Organizational Design

Vir Biotechnology is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies. 

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

Vir Biotechnology is looking for a Senior Director, Organizational Design, who will be responsible for leading organizational design and effectiveness strategies that support Vir Bio’s mission during an exciting period of evolution in the company’s growth. This role will report to the Head of HR.

Operating at the intersection of talent strategy, workforce planning, and enterprise transformation, this role partners closely with senior leaders, HR Business Partners, and cross-functional stakeholders to identify, build, and enable scalable workforce solutions.

This leader will bring data-informed insights, strong facilitation skills, and pragmatic change leadership to complex, high-stakes business challenges typical of a rapidly scaling immuno-oncology organization. You will develop OD strategies that reinforce Vir Bio’s patient-focused, high-accountability culture.

The role will provide expert technical expertise, facilitation and advisory support while ensuring business leaders and HRBPs retain clear accountability for business decisions, execution and outcomes.

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

Organizational Design & Effectiveness

• Lead organizational design initiatives and operating model evolutions across functional and matrixed teams.
• Support senior leaders and HRBPs in diagnosing organizational effectiveness challenges and suggest solutions.
• In close partnership with HRBPs, Finance, and business leaders, translate business and scientific roadmaps into workforce implications and scenarios.
• Define and evolve enterprise workforce architecture standards (e.g., role clarity, capability models, span/layer principles)
• Build tools and develop insights enabling proactive workforce planning that integrates into long-range talent processes; ensure the organization scales ahead of demand rather than reactively.

Change Management & Organizational Readiness

• Develop change management strategies for OD and organizational effectiveness initiatives.
• Act as a trusted advisor during periods of ambiguity, transformation, and rapid growth.
• Assess organizational health and readiness for change, partner with HRBPs and business leaders to support teams through transitions.

Data, Insights & Measurement

• Establish metrics and diagnostics to assess organizational effectiveness.
• Partner with HR and business leaders to translate insights into clear narratives and options that influence decision-making at the enterprise level.
• Track impact of OD/OE initiatives to inform continuous improvement and organizational learning.

Capability Building & Scaled Solutions

• Build and deploy scalable and self-sustaining OD/OE frameworks and resources including digital and AI-enhanced tools.
• Partner with other HR COEs to integrate OD/OE practices into the HR operating model including talent reviews, succession planning, and leadership development.
• Maintain a strong external network (coaches, facilitators, researchers) to supplement internal capability as needed.

• Bachelor’s degree required; advanced degree (e.g., MBA, OD, I/O Psychology, HR or related field) strongly preferred.
• 12–15+ years of progressive experience in organizational design, organizational effectiveness, talent strategy, workforce transformation, or internal consulting.
• Experience supporting late-stage or commercial-stage biotech/pharma organizations with a focus on oncology or immuno-oncology required
• Demonstrated success partnering with senior leaders on complex, enterprise-level organizational challenges.
• Deep expertise in organizational design, team effectiveness, leadership development, and change management.
• Strong facilitation, coaching, and executive influence skills; executive coaching certification and/or substantial coaching experience is a plus.
• Enterprise mindset with the ability to connect organizational decisions to scientific, clinical, and commercial outcomes.
• Proven ability to build trusting, collaborative partnerships with diverse stakeholders across functions and levels.