Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer.
Overview
Senior Director, Data Sciences and Analytics, provides leadership to the Data Sciences and Analytics Department and provides influence across the Clinical Development organization. As a leader of the Data Science and Analytics organization, and part of a cross-functional team of drug development scientists focused on providing hands on skills, expertise, and tools to facilitate access, integration, visualization, and exploratory analysis of complex and diverse data in support of clinical development activities and decisions. The Data Science Lead will drive all clinical data management activities, as well as execution of exploratory analysis for scientific considerations related to drug development and clinical study design. Through practical hands-on work, the Data Science Lead will define approaches, processes, algorithms, and tools that support the analytics, visualizations, and decision support needs of drug development scientists and projects. The Data Science Lead will play a key role in building the team with the necessary skills, build relationships with relevant stakeholders, and implement relevant tools and approaches. The Data Science Lead will collaborate with Biostatistics leads and other members of drug development teams to ensure connectivity of exploratory analysis work in support of development, regulatory approval, and market acceptance of products. This position includes functional management responsibilities.
Essential Functions and Responsibilities
- Lead a team with diverse expertise to drive the data science objectives across early to late-phase drug development.
- Responsible for all clinical data management activities and assignments including training personnel to the tasks required to operationalize current and future studies.
- Develop novel ways of integrating, mining, and visualizing diverse, high-dimensional data sets.
- Develop and apply novel or existing computational methods for patient segmentation from multimodal clinical and omics datasets for various treatment modalities in partnership with Translational, Informatics, Clinical and Statistical scientists.
- Develop, validate, and implement predictive models, and deploy automated processes for producing modeling results at scale.
- Generate novel insights from data and present them via rich and intuitive visualizations.
- Builds successful partnerships and seamless interfaces within the department and the broader research and development organization. Communicates proactively and effectively across several teams with diverse subject matter expertise.
- Ensures quality of deliverables by consistently applying analysis and reporting standards, and driving compliance with regulatory requirements, corporate and departmental SOPs, and work practices.
- Drives the development and implementation of innovative strategies and technologies.
- Independently develops, troubleshoots, and maintains complex programs and utilities in accordance with predefined specifications and build upon existing Iovance standards.
- Provides technical guidance to external partners concerning project and data standards, and analysis practices to ensure efficient and integrated project strategies.
- Understands software development methodologies and appropriately applies those methodologies.
- Identifies opportunities for increased efficiency and consistency within the organization and provides SME support to continuous improvement initiatives.
- Adheres to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics.
- Performs miscellaneous duties as assigned.
Required Education, Skills, and Knowledge
- 8+ years of leadership of Clinical Data Management function required
- PhD in a relative quantitative field (i.e., Biostatistics, Statistics, Bioinformatics, Computer Science, etc.,)
- Excellent verbal and written communication skills and strong interpersonal skills are required.
- Demonstrated ability to develop and lead a team of individuals with diverse experience and expertise.
- Mastery in clinical data management systems and industry wide thesauri
- Ability to explain technically complex information for a non-technical audience.
- Strong positive attitude, thrives in a dynamic, fast paced environment with many simultaneous projects
- Demonstrates the ability to work within budget constraints, while utilizing resources efficiently and in a fiscally responsible manner
Preferred Education, Skills, and Knowledge
- Experience with oncology drug development is highly desirable.
The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodations may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request an accommodation.
Physical Demands and Activities Required
- Must be able to remain in a stationary position standing or sitting for prolonged periods of time.
- Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects.
- Must have visual acuity to perform activities such as: preparing and analyzing data and figures, viewing a computer screen, and extensive reading.
- This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers.
- Must be able to communicate with others to exchange information.
Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines.
Work Environment
This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards.
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The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time.
Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact [email protected].
By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.
Top Skills
What We Do
Iovance Biotherapeutics (NASDAQ: IOVA) aims to improve patient care for people living with cancer. Iovance is investigating T cell-based therapies, known as tumor infiltrating lymphocytes (TIL), which use a patient’s own immune cells to attack cancer. Our unique Iovance TIL technology platform has generated novel cell therapies that are currently in clinical studies for multiple cancers.
We are adding to our talented team as we actively prepare for our initial commercial launch, advance our research and development efforts, and build our internal manufacturing capabilities. Iovance is headquartered in the San Francisco Bay Area. Our Iovance Cell Therapy Center (iCTC), a state-of-the-art manufacturing facility, is located in Philadelphia. We also have a research site in Tampa, Florida.
Any information expressed by Iovance is subject to the risk factors and information on forward-looking statements contained in its filings with the Securities and Exchange Commission and available here: https://ir.iovance.com/sec-filings
