Senior Data Scientist, Gen AI Application

Posted 14 Days Ago
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South San Francisco, CA, USA
In-Office
177K-329K Annually
Senior level
Healthtech • Biotech
The Role
Design and build multi-agent Generative AI business applications, architect RAG-based retrieval and multimodal systems, collaborate with product and infrastructure teams to align UX and capabilities, drive observability and performance optimization, ensure regulatory compliance, mentor stakeholders, and influence technical priorities across the enterprise.
Summary Generated by Built In

Why Genentech
We're passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly pursuing answers to the world's most complex health challenges and transforming society.

Genentech's Data, Digital, and Analytics (DDA) team is dedicated to solving complex healthcare challenges and improving patient outcomes. DDA empowers business partners across Commercial, Medical, and Government Affairs (CMG) to make impactful decisions by leveraging data, analytics, and AI/ML to enable fast, targeted actions in rapidly evolving business contexts. DDA fosters a unified understanding of customers, actions, and outcomes by transforming the business insight supply chain from the traditional reactive service model to a modern proactive product model, which integrates analytics and insights seamlessly into CMG's evolving digital, data, and automation platforms, creating scalable solutions and eliminating silos. In DDA, you will work as a trusted, objective advisor and expert, recommending critical decisions and actions to be taken with credibility and a focus on driving measurable impact. You will be part of a diverse, inclusive team that reflects the world we serve, thriving in a welcoming culture built on collaboration and innovation.

The Opportunity
The Sr. Data Scientist – Generative AI Application Specialist builds what users actually touch: the conversational, agentic, and GenAI-workflow applications that turn our AI capabilities into products people trust and rely on. This is a front-end-led, full-stack role for the age of AI. You will own the experience layer where reasoning agents, streaming responses, and generative interfaces meet real users, and you will partner closely with infrastructure and product teams to
make those experiences fast, legible, and reliable. We are not looking for a traditional data scientist, a UI-only developer, or someone who only “vibe-codes” with an assistant. We are looking for a strong engineer who is redefining what front-end means when the interface is a living, reasoning system — while representing the team’s expertise across the broader Genentech and global Roche organizations.

  • Build AI-Native Applications: Design and ship production front-ends for conversational and agentic experiences — chat, multimodal, and generative/adaptive UI — that make complex GenAI workflows feel simple, transparent, and trustworthy.

  • Master Real-Time & Streaming Interaction: Architect the real-time layer

  • (WebSockets/SSE, token streaming, live agent status, interruptibility, optimistic and latency-aware UI) so conversations and long-running agent tasks feel responsive and alive.

  • Design the UI as an Agent Surface: Build interfaces that agents can read and act on — tool-call visualization, human-in-the-loop controls, and “UI-as-context” patterns that let assistants ground their answers in what the user is actually seeing.

  • Deliver Conversational & Multimodal UX: Craft chat and (over time) voice/multimodal interactions, surfacing memory, state, and reasoning in ways that build user trust and keep humans in control.

  • Own Front-End Craft & Engineering Fundamentals: Deliver well-architected, accessible, performant React/TypeScript applications backed by a real component and design system. This is solid, durable front-end engineering — not throwaway prototypes or assistant-generated code you cannot stand behind.

  • Bridge Front-End and Agentic Systems: Partner with infrastructure and orchestration teams to design the contracts between the app and the agents/GenAI workflows behind it, shaping how state, memory, and context flow across the full stack.

  • Set Direction & Elevate AI Literacy: Act as a technical coach and pattern-setter,

  • influencing technical priorities and elevating how the wider organization thinks about interaction, trust, and transparency in AI-native products.

  • Operate with Rigor in a Regulated Environment: Manage high-stakes internal and external partnerships while ensuring all work adheres to global compliance, security, and regulatory standards.

Who You Are

  • Bachelor's degree and 5+ years of experience building software, with a strong emphasis on front-end and application engineering.

  • Front-End Engineering Depth: Expert-level React and TypeScript (or an equivalent modern framework), with deep command of component architecture, state management, accessibility, and performance — a real engineer who writes and reviews production code, not solely AI-generated output.

  • Real-Time & Streaming Experience: Hands-on experience with WebSockets, SSE, and streaming interfaces (e.g., token-by-token responses, live status, and interruptible or long-running tasks).

  • GenAI Application Fluency: 3+ years building GenAI-powered or conversational

  • products, with practical understanding of agents, prompting, tool-calling, RAG, and the trade-offs of GenAI workflow design.

  • Conversational & Generative UI: Experience designing chat, multimodal, and/or

  • adaptive/generative interfaces, and a thoughtful approach to keeping humans in the loop, building trust, and grounding responses in what is on screen.

  • API & Systems Integration: Comfort integrating front-ends with agent/LLM backends and APIs (REST, event-driven patterns, MCP/A2A), and reasoning about cost, latency, reliability, and observability across the AI system end to end.

  • Communication & Collaboration: Ability to partner with product, design, and

  • infrastructure teams and to translate complex technical trade-offs for non-technical stakeholders.

Preferred

  • AI-Native Interaction Patterns: A point of view on how front-end is evolving in the age of AI — generative UI, agent-readable interfaces, UI-as-context, and novel interaction models beyond the chatbox.

  • Design & Craft: Strong design sensibility and fluency with design-to-code workflows (Figma), motion/polish, and building and maintaining a design system.

  • Voice & Multimodal: Experience with voice and other multimodal GenAI interfaces.

  • Full-Stack Range: Comfort reaching into the agent and orchestration layer (LangChain, LangGraph, AWS Agentcore) when the experience requires it.

  • Industry Experience: Experience in healthcare, pharmaceutical, or other highly regulated industries.

  • Security Protocols: Familiarity with common security protocols and building software under regulatory constraints.

  • Enterprise Navigation: Proven ability to influence technical priorities and manage partnerships within a large-scale, global corporate structure.

  • Resilience & Risk Management: Experience leading “fail-forward” initiatives where rapid prototyping and business-value trade-offs are prioritized.

Location
This position is based in South San Francisco, CA and offers a hybrid schedule working 3 days per week on campus.
Relocation benefits are not available for this posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $177,310 - $329,290. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Skills Required

  • Bachelor's degree and 5+ years of experience in a relevant field.
  • Minimum 3+ years building B2B Generative AI products, focusing on agentic design trade-offs, prompting, and data handling.
  • Mastery of RAG architecture (including chunking optimization), vector and graph databases, reranking algorithms, and multi-modal application development.
  • Hands-on experience with agentic frameworks and tools (LangChain, LangGraph, AWS Agentcore), MCP and A2A protocols, and modern UI tools (React, Angular, Figma).
  • Expert-level command of observability tools and evaluation methodologies to manage cost, reliability, latency, and performance in agentic systems.
  • Advanced SQL proficiency (including AI-generated SQL) and ability to translate complex technical analyses for non-technical stakeholders.
  • Ability to manage high-stakes internal and external partnerships and ensure adherence to global compliance and regulatory standards.
  • Experience with multimodal Gen AI tools (including multimodal development).
  • Experience designing UI for enterprise software and familiarity with front-end design workflows/prototyping (Figma).
  • Experience with security common protocols.
  • Experience in healthcare, pharmaceutical, or other highly regulated industries.
  • Proven ability to influence technical priorities and navigate large-scale, global enterprise organizations.
  • Experience leading rapid prototyping, fail-forward initiatives, and risk management trade-offs.

Genentech Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.

  • Healthcare Strength Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
  • Retirement Support Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
  • Leave & Time Off Breadth Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.

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The Company
HQ: South San Francisco, CA
20,069 Employees
Year Founded: 1976

What We Do

Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.

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