Senior Data Architect – AWS & Databricks Modernization

CTI MD Tech@Lilly 
Senior Data Architect — AWS & Databricks Modernization at Scale 

Position Description 

About Lilly 

At Lilly, everything we do starts with patients. We unite caring with discovery to make life better for people around the world. Headquartered in Indianapolis, Indiana, our global team of over 50,000 employees work with urgency and purpose to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. We bring our best to this work because people depend on it. If you're driven by purpose and determined to make a meaningful difference for patients, we invite you to bring your skill and your commitment to Lilly. 

About Technology@Lilly 

At Lilly, technology is not a support function. It is how a global medicine company operates, innovates, and delivers. Lilly in Bengaluru builds the capabilities that make this possible, cloud platforms, AI systems, and automation at enterprise scale, all in service of a purpose that makes this technology work genuinely distinctive, from advancing drug discovery to enabling connected clinical trials to keeping a global medicine company running at the standard patients deserve. 

About the Business Function: 

The Clinical & Non-Clinical Data Organization at Eli Lilly and Company is responsible for the design, build, and operation of enterprise data platforms that power drug discovery, clinical development, and regulatory submissions. Data Hub is building a robust Data Strategy to make Lilly's Clinical and Non-Clinical data AI-ready and audit-ready, delivering scalable, governed, and reusable data products that accelerate how medicines reach patients. Our data engineering organization sits at the intersection of science, technology, and patient impact — connecting Clinical and Non-Clinical data across the full chain, from ingestion to consumption. 

Role: 

Senior Data Architect — AWS + Databricks Modernization at Scale 

The Senior Data Architect (R5) is a hands-on Databricks and lakehouse modernization leader who owns the architecture and execution of large-scale migrations from legacy warehouses and point platforms onto a unified Databricks lakehouse for the Clinical and Non-Clinical data domain. This is a builder role: the architect writes code, builds migration pipelines, and personally ships production lakehouse assets — in addition to defining the modernization roadmap and rollout patterns that scale across dozens of domains. The role also owns the roadmap for semantic modeling and analytics-ready data, builds reusable data products the organization can adopt, drives data quality on clinical data specifically, and defines the metrics that enable data-driven decision making. AI-assisted and agentic ways of working are the expected default. Domain knowledge of the clinical data landscape is an added advantage. This role is split 70% hands-on technical execution including coding and 30% strategy, and shapes the future technology landscape. 

Key Responsibilities: 

Lakehouse Modernization & Migration at Scale (Hands-On) 

• Own the technical roadmap and execution for migrating legacy warehouses, on-prem databases, and point data platforms onto Databricks — sequencing dozens of Clinical and Non-Clinical domains with minimal disruption. 

• Personally build migration pipelines and re-platforming accelerators (schema conversion, historical backfill, dual-run validation, cutover automation) that move data at scale with parity and auditability. 

• Define reusable modernization patterns — landing zone design, medallion (bronze/silver/gold) conventions, workspace/catalog topology — that scale consistently as new domains onboard. 

• Right-size and standardize the Databricks platform footprint across environments (dev/test/prod, multiple workspaces) for cost, performance, and governance at enterprise scale. 

• Establish cutover, rollback, and data-reconciliation practices that de-risk large-scale migrations in a regulated environment. 

Databricks Lakehouse Architecture & Engineering (Hands-On) 

• Architect and build the Clinical/Non-Clinical lakehouse on Databricks, applying medallion design across Delta Lake tables at scale across multiple domains. 

• Personally build and optimize Delta Live Tables (DLT) pipelines, Databricks Workflows, and PySpark/Spark SQL jobs for high-volume ingestion, transformation, and curation. 

• Own Unity Catalog design and rollout — catalogs, schemas, access control, lineage, and data sharing — as the governance backbone across an expanding domain footprint. 

• Tune performance and cost at scale: Photon, cluster policies, job/task orchestration, auto-scaling, and Databricks SQL Serverless warehouses across many concurrent workloads. 

• Package and deploy pipelines using Databricks Asset Bundles and CI/CD; evaluate Lakehouse Federation and cross-workspace patterns for enterprise-wide access. 

AI-Native & Agentic Data Engineering 

• Use AI-assisted and agentic tooling by default — migration gap analysis, pipeline scaffolding, code conversion, and documentation — to accelerate modernization at scale. 

• Apply Databricks Mosaic AI / MLflow and LLM-based tooling to automate schema mapping, ontology alignment, and data-quality scoring during migration. 

• Build reusable AI-assisted accelerators that other engineers and architects reuse to modernize additional domains faster. 

Semantic Modeling, Analytics-Ready Data & Reusable Data Products 

• Define and own the multi-quarter roadmap for semantic modeling and analytics-ready data — ontologies, taxonomies, dimensional models, and semantic layers — across Clinical and Non-Clinical domains. 

• Design and build reusable, governed data products (documented, discoverable, versioned) on the lakehouse that other squads can adopt directly rather than rebuilding equivalents. 

• Own data quality specifically for clinical data — define quality rules, thresholds, and remediation workflows for clinical data sets, and track quality trends over time. 

• Define the metrics and KPIs (data quality scores, product adoption/reuse rates, pipeline reliability, time-to-insight) that enable data-driven decision making across the India data organization, and report progress against the roadmap. 

Governance, Standards & Automation 

• Implement role-based and attribute-based access control and encryption for data at rest and in transit within Unity Catalog, consistently across every migrated domain. 

• Stand up and maintain the data standards platform — the reference implementation, templates, and lineage/quality practices for how Clinical and Non-Clinical data is modeled and migrated. 

• Automate lineage capture, schema-drift detection, and post-migration data-quality validation so the team scales modernization without proportional manual effort. 

Collaboration & Stakeholder Engagement 

• Partner with business SMEs, solution architects, and engineering teams to sequence and translate legacy platform needs into Databricks-based modernization plans. 

• Communicate migration risk, trade-offs, and rollout progress clearly to technical and non-technical stakeholders, and own the India lakehouse modernization roadmap. 

Qualifications Required: 

Required — Lakehouse Modernization at Scale (Must-Have, Hands-On) 

• 5+ years hands-on experience migrating or modernizing legacy data warehouses/on-prem platforms (e.g., Oracle, Teradata, SQL Server, Hadoop) onto a Databricks lakehouse in production. 

• Demonstrated experience sequencing and delivering multi-domain migrations at enterprise scale — not a single one-off project. 

• Hands-on experience with schema conversion, historical backfill, dual-run/parallel validation, and cutover automation for large-scale data migrations. 

• Experience standardizing workspace, catalog, and environment topology (dev/test/prod, multi-workspace) across a growing platform footprint. 

Required — Databricks & Lakehouse Engineering (Must-Have) 

• 5+ years hands-on building on Databricks: Delta Lake, Delta Live Tables, Unity Catalog, Databricks Workflows, Databricks SQL, and MLflow, with real production pipelines shipped, not design-only. 

• Strong PySpark and Spark SQL engineering skill, including performance tuning, cluster sizing, and cost optimization at scale. 

• Experience with Delta table optimization (Z-ordering, OPTIMIZE/VACUUM, liquid clustering) and Databricks Asset Bundles / Git-based CI/CD / infrastructure-as-code. 

Required — Semantic Modeling, Data Products & Quality 

• Proven experience defining and delivering a semantic modeling / analytics-ready data roadmap: ontologies, taxonomies, dimensional models, and semantic layers, built and shipped, not design-on-paper. 

• Track record designing and shipping reusable, governed data products that other teams adopt, with clear documentation and ownership. 

• Hands-on experience defining and driving data quality frameworks — rules, thresholds, scorecards, remediation — specifically on clinical data sets. 

• Experience defining metrics/KPIs that support data-driven decision making and communicating them to business and technical stakeholders. 

Required — AI-Assisted & Platform Governance 

• Demonstrated, current use of AI-assisted/agentic tools as the default method for migration analysis, pipeline design, and documentation. 

• Hands-on experience with cloud platforms (AWS) and Unity Catalog-based access control, encryption, and lineage/compliance patterns for regulated data. 

Preferred 

• Databricks certifications (Data Engineer Professional, Databricks Certified Associate/Professional); prior experience leading an enterprise-wide legacy-to-lakehouse modernization program in a regulated industry. 

• Domain knowledge of the clinical data landscape (e.g., CDISC/SDTM/ADaM, EDC systems, clinical trial data structures) is an added advantage; familiarity with GxP / 21 CFR Part 11 compliance in a validated data environment. 

Education & Experience: 

Minimum 

• Bachelor's degree in Computer Science, Information Systems, or related discipline. 

• 12+ years in data architecture/engineering, including 3+ years hands-on leading Databricks-based lakehouse modernization or migration at scale. 

• Demonstrated track record shipping large-scale migration and modernization work to production on Clinical and/or Non-Clinical data, not solely design-on-paper. 

• Demonstrated, current use of AI-assisted tools in day-to-day design and engineering work, with concrete examples. 

Preferred 

• Master's degree or equivalent in a quantitative or engineering discipline. 

• Experience in a regulated industry (pharma, life sciences, finance) with GxP or equivalent compliance requirements. 

• Prior contribution to clinical or non-clinical data programs supporting IND, NDA, or BLA submissions; working knowledge of the clinical data landscape is an added advantage. 

Preferred: 

• Master's degree or equivalent in a quantitative or engineering discipline. 

• Databricks certifications such as Data Engineer Professional, Databricks Certified Associate/Professional. 

• Prior experience leading an enterprise-wide legacy-to-lakehouse modernization program in a regulated industry. 

• Domain knowledge of the clinical data landscape including CDISC, SDTM, ADaM, EDC systems, and clinical trial data structures. 

• Experience in a regulated industry such as pharma, life sciences, or finance with GxP or equivalent compliance requirements. 

• Prior contribution to clinical or non-clinical data programs supporting IND, NDA, or BLA submissions. 

At Lilly, caring is not only what we do for patients. It is how we work. We believe the people who dedicate themselves to making medicines better deserve an environment that makes their lives better too, one where they are supported, respected, and given the space to do their best work. This is not just a policy. It is who we are. 

Equal Opportunity & Accommodation 

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form at https://careers.lilly.com/us/en/workplace-accommodation for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. 

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, colour, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.