Title: Scientist
Location: Hayward, CA
Reports To: Director
Company
Frontage Laboratories Inc. is an award winning, publicly listed, full-service CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada, and China, growing significant growth. Our core competencies include pre-clinical, drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Position/Job Summary
We are seeking a highly motivated and experienced Scientist specializing in LC-MS/MS to join our dynamic team. This individual will play a pivotal role in quantitative bioanalysis and the characterization and identification of drug metabolites, contributing to our understanding of DMPK (Drug Metabolism and Pharmacokinetics) and its impact on drug safety and efficacy.
Roles & Responsibilities
- Develop and optimize sample preparation and analytical methodology for quantitative measurement of drugs in a variety of modalities and metabolite profiling/identification using state-of-the-art LC-MS/MS and high-resolution mass spectrometry (HRMS).
- Lead and execute LC-MS/MS-based projects in a timely and high-quality manner.Interact with clients to provide actionable insights on method development and sample analysis-related challenges.
- Operate, maintain, and troubleshooting LC-MS/MS instruments; serve as instrument lead as needed.
- Prepare and review scientific reports, presentations, and regulatory documents to ensure accuracy and compliance with industry standards.
- Stay updated on advancements in LC-MS/MS technologies and methodologies.
- Collaborate with cross-functional teams and provide technical guidance when needed.
- Mentor and train junior lab staff.
Education, Experience & Skills Required
- Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field.
- Solid hands-on experience with LC-MS/MS-based bioanalytical method development including sample preparation, instrument operation and data processing.
- Proven track record operating LC-MS/MS systems in a bioanalytical lab
- Strong expertise in drug metabolism and biotransformation, with hands-on experience in metabolite identification using LC-MS/MS and HRMS.
- Demonstrated ability to analyze and interpret complex mass spectrometry data and provide detailed reports.
- Excellent communication skills and ability to work both independently and collaboratively in a cross-functional team environment.
- Experience in pharma or biotech environment is a plus
Salary and Benefits:
Frontage Laboratories offers a competitive compensation and generous benefits package including health and dental insurance, a 401(k) plan, health insurance, short and long-term disability insurance, life insurance etc
Salary Range: $80,000 to $110,000
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
Skills Required
- Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field
- Solid hands-on experience with LC-MS/MS-based bioanalytical method development
- Proven track record operating LC-MS/MS systems in a bioanalytical lab
- Strong expertise in drug metabolism and biotransformation
What We Do
Frontage Laboratories, Inc. is a CRO that provides integrated, science-driven, product development services throughout the drug discovery and development process to enable pharmaceutical and biotechnology companies to achieve their development goals. Comprehensive services include drug metabolism and pharmacokinetics, analytical testing and formulation development, preclinical and clinical trial material manufacturing, bioanalysis, preclinical safety and toxicology assessment and early phase clinical studies. Frontage has enabled many biotechnology companies and leading pharmaceutical companies of varying sizes to advance a myriad of molecules through development and file regulatory submissions in the United States, China and other countries.
