Inflammatix Portugal is seeking a highly motivated Scientist Level II to contribute to assay development activities supporting microfluidic test system development. The successful candidate will play a key role in advancing our research and development projects, particularly in the areas of ultra-rapid sample preparation, isothermal amplification protocols, and microfluidic device development. This role is laboratory-based and requires exceptional attention to detail. This role will involve development of novel sample preparation methods and Design of Experiments-based (DOE-based) optimization of existing chemistries. The successful candidate will work collaboratively within a multidisciplinary team to achieve project goals and drive innovation.
PRIMARY RESPONSIBILITIES:
- Design, develop, and optimize molec ular assays, including but not limited to various PCR techniques (e.g., qPCR, RT-qPCR), isothermal amplification (qLAMP, RT-qLAMP), and nucleic acid isolation and manipulation.
- Design primers for use in molecular assays and ensure their specificity and efficiency.
- Conduct experiments to validate assay performance and troubleshoot issues as needed.
- Analyze and interpret complex data sets to guide the development and optimization of assays.
- Support translation of ultra-rapid chemistries from the bench top to a microfluidic device.
- Collaborate with cross-functional teams, including product development, manufacturing and quality control, to integrate assay development with product pipelines.
- Maintain a detailed research log and summarize work in research reports and presentations.
- Present research findings, project updates, and technical information to internal and external stakeholders.
- Stay up to date with the latest advancements in molecular biology and related fields to incorporate innovative approaches into assay development.
- Mentor and provide technical guidance to junior scientists and research associates.
QUALIFICATIONS:
- Ph.D. in Molecular Biology, Biochemistry, Genetics or related field with a minimum of 2-4 years industry R&D experience.
- In-depth knowledge and hands-on experience with a broad range of molecular biology techniques, including but not limited to, various PCR techniques, Loop-mediated isothermal amplification (LAMP) and nucleic acid isolation and manipulation, and primer design.
- Strong analytical skills with the ability to interpret and present complex data effectively.
- Strong attention to detail, self-motivation, good organizational skills, ability to prioritize and multi-task, and able to work both independently and as part of a team
- Experience with automation and high-throughput assay development is a plus.
- Experience working with clinical samples.
KNOWLEDGE, SKILLS, AND ABILITIES:
- Knowledge of DOE-based assay optimization is a plus
- Prior work with microfluidic systems is a plus
- Comfortable working in a BSL2 environment
- Proven interpersonal, communication, and presentation skills
- Proficient with Microsoft office suite of programs
- Proficient with one or more common graphical analysis software(s) (RStudio, Graphpad Prism, Minitab, etc.)
COMPENSATION AND CLASSIFICATION:
- Classification: Full-time position
- Compensation: Package is competitive/commensurate with experience
- Benefits: Medical insurance
- Location: Lisbon, Portugal
Top Skills
What We Do
Inflammatix is developing an innovative point-of-care instrument platform to be used with a test to aid in the diagnosis of acute infection and sepsis by harnessing the immune system to deliver advanced immune response diagnostics. Our test rapidly informs the clinician about the likelihood of bacterial or viral infection and the need for ICU level care in the emergency department. Faster results may translate into more timely and appropriate therapy and level of care decisions.
*Products in development, are not for sale, and do not have marketing approval or clearance from regulatory authorities in any jurisdiction.
