We are currently recruiting an Scientist II or Senior Scientist (dependant on experience) to join our team based in Alderley park.
Role: Scientist II or Senior Scientist – Analytical Sciences
Salary: Excellent salary package, plus excellent benefits
Hours: Full time, 37.5 hours per week
Location: Alderley Park, Macclesfield, SK10 4TG.
Our Company
Cyprotex vision is to be pioneers of innovative ADME-Tox partnerships, driving delivery of safer and more effective medicines. With state-of-the-art facilities and technical expertise, we specialise in in vitro and in silico ADME-Tox services, providing a wide range of assays tailored to our client’s needs. This includes in vitro screening to support discovery projects, regulatory studies to support preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models and PBPK/QSAR modelling expertise. As well as supporting clients directly, we have a strong focus on R&D.
Our Alderley Park site is set in the heart of Cheshire surrounded by stunning 400-acre estate, open green spaces, sweeping viewpoints, all within easy reach of Merseyside and Greater Manchester, Staffordshire, and Shropshire. Easy access to public transport.
Key Responsibilities:
Scientist II or Senior Scientist (Met ID) within Analytical Sciences
Cyprotex, part of the Evotec group are recruiting a Scientist to join our Analytical Team based at Alderley Park, Cheshire, UK.
We are seeking an individual with analytical experience to work on Metabolite Identification studies. Analytical experience should ideally have been obtained within a discovery or bioanalytical environment either as a post-graduate or from working within the industry. A minimum of a BSc in a relevant field is required. Hands-on experience of maintaining and using LC-MS/MS systems in support of small molecule Metabolite Identification projects is desirable.
Primary Responsibilities:
- Development of customised LC-MS/MS methods to support Metabolite ID studies.
-
Troubleshooting and system maintenance and co-ordination of engineer visits.
-
Running the analytical phase of Metabolite ID studies with involvement in high-resolution MS/MS analysis, structural elucidation and reporting.
-
Setup and running of reactive metabolite assays including analysis and reporting.
-
Contributing to our Quality System via preparation and review of SOPs.
-
Collaborating effectively with our Information Systems Team to implement data processing tools. Seeking opportunities to form additional collaborative relationships.
-
Promote and support a continuous improvement culture.
Additional Responsibilities may include:
-
Contributing to the scheduling of lab activities and resources.
-
Flexing into other analytical areas to provide resource/cover given suitable training and supervision.
-
Working with assay scientists to maximise quality and throughput.
Knowledge, Skills and Abilities
Essential:
-
Hands-on experience of utilising LC-MS/MS techniques for analysis of small and large molecules in invitro and invivo samples from within a discovery, development or CRO setting.
-
A knowledge of DMPK/ADME assays within drug discovery/development.
-
The ability to perform routine maintenance on LC-MS/MS equipment.
-
A high level of attention to detail and well organised with an ability to work without close supervision.
-
Ability to adapt to changing priorities, manage multiple activities simultaneously and to achieve timelines.
-
Motivational team player with a high level of dedication.
-
Extensive computer literacy including use of Microsoft Office.
-
Ability to learn new techniques and processes at a fast pace.
Preferred but not essential
-
Advanced LC-MS/MS maintenance skills.
-
Experience with MassLynx™, Analyst™ or other Mass Spectrometry data-acquisition software packages.
-
Experience of metabolite profiling software e.g. Metabolynx, Metabolite Pilot or UNIFI.
-
A wider knowledge of analytical support in drug discovery/development (e.g. bioanalytical method validation).
Qualifications
- Minimum BSc in relevant scientific discipline covering chemistry.
Rewards and Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits, which include amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
We aim to recruit and retain the best because our work is challenging and requires the most competent staff. We look for talented individuals from all walks-of life, educational backgrounds and nationalities, to provide the expertise and dedication to enable us to achieve continual success in everything we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
We offer a competitive salary and benefits package for all permanent employees.
- Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution and the employer will match the increase up to a maximum of 7.5%.
- 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days.
- Private health insurance with BUPA for the employee and their partner/family under the company scheme
- Wellbeing support 24/7 and counselling services
- Permanent health insurance provides 75% of the base salary after the qualifying period.
- Private dental cover, on completion (but not subject to) of your 3-month probationary period
- Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
- Career progression within the company, we have excellent training and support and continuing professional development opportunities.
- Cycle-to-work scheme
- Refer a friend scheme, team and annual events, recognition awards and many more.
Onsite Facilities
- The company pays for secure onsite parking.
- Restaurant, café, and a gastro pub
- Gym and workout studio, running, walking, and cycling routes.
- Good public transport links.
Interested?
Apply NOW – please upload your up-to-date CV and cover letter to Workday via our careers page
FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.
ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.
Top Skills
What We Do
Evotec is a biotechnology company that is committed to advancing drug discovery and development. Through flexible business models, we collaborate with pharmaceutical companies, biotechs, foundations, and government agencies on a substantial scale. We believe that by working together, we can make a difference in the lives of patients.
Our Pipeline Co-Creation model represents our adaptable, multi-modality, fully integrated end-to-end approach to drive collaborations and services across all phases of drug discovery and development – from discovery of novel targets to achieving Proof of Concept in the clinic and into commercial manufacturing.
We aspire to contribute data-driven disease understanding and early disease relevance in humans to bring the probability of success up. We select the right modality, which is then propelled forward on our platforms by our passionate people striving for the fastest and most effective ways towards patient impact. This is enabled by convergence of human ingenuity with data and AI.
We also offer specific solutions, products, and CRO/CDMO-like services, always in support of the Biopharma R&D innovator. Our more than 4,000 scientists work closely with numerous partners concurrently, delivering fully integrated research and development portfolios or individual projects with the highest quality standards and efficiency, coupled with great science, passion, engagement, and communication.
