When you work as a Scientist II in the Mass Spec Bioanalysis Development group at KCAS, you get to further our mission by leveraging your knowledge in bioanalytical and scientific principles to independently execute defined aspects of studies, from study setup through data generation, as well as support development activities. You will utilize your scientific foundation to assess data integrity and troubleshoot with limited oversight.
Our Mass Spec Bioanalysis Development team uses LCMS (Liquid Chromatography Mass Spectrometry) techniques to conduct sophisticated sample preparation to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.
In this role, we will rely on you to:
- Execute study activities including sample preparation (extractions, enrichments/affinity capture, digestions), LCMS analysis, and data processing with limited supervision
- Support method development, qualification, and optimization activities
- Troubleshoot technical issues and propose solutions with limited guidance
- Analyze data and prepare summaries for senior scientists to aid in client updates
- Ensure compliance of study activities with pertinent portions of study protocol, SOPs & regulatory requirements
- Communicate study progress and risks to senior staff
- Provide informal guidance to junior staff as needed
- Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values
To qualify specifically for this role, you will have:
- Bachelor’s or master’s in chemistry, Biochemistry or chemical/biochemical engineering, or related field with at least 2–4 years of experience with LC-MS/MS
- Hands-on experience with bioanalytical sample preparation, quantitative LC-MS/MS, and chromatography
- Experience supporting method development, qualification, and troubleshooting
- Experience with small molecule analysis; proteins, peptides, or biomarkers experience preferred
- Familiarity with reversed phase or HILIC chromatography and standard bioanalytical workflows
- Experience working in a regulated environment (GLP/GxP) preferred
What We Do
With its presence in three locations across North America and Europe, KCAS Bio is a leading contract research organization (CRO) employing top scientific talent and providing comprehensive bioanalytical services to the global biopharmaceutical industry from early discovery support through product registration and beyond. The collaboration of the three entities allows for global support in bioanalytical, biomarker, immunogenicity, cellular and molecular assay services along with clinical kitting and sample management. The KCAS family of companies operates in state-of-the-art facilities in the United States and Europe. This business structure enables the expertise, capacity, and flexibility to support the development of all types of drugs, biologics, cell and gene therapies to improve health worldwide. Our purpose is to help accelerate the discovery and development of life-changing drugs smoothly, safely and sustainably.
