The Opportunity
The Department of Immunology at Genentech is seeking a highly talented, driven and motivated Scientist 3 to investigate novel biological mechanisms and potential therapeutic targets to treat inflammatory diseases. The successful candidate will lead projects that advance our understanding of the cellular and molecular mechanisms of adaptive and innate immunity, with a main emphasis on harnessing immunoregulatory mechanisms for reestablishing immune and tissue homeostasis under inflammatory conditions.
The candidate will be expected to work independently and collaboratively on pipeline projects and will be responsible for advancing exciting and novel research stage programs into early clinical development, providing both scientific and technical expertise and generating solid proof of concept data. Prior industry experience is required, particularly in target discovery. Excellent communication skills, will facilitate fruitful and open collaborations with other labs in immunology, regenerative medicine, human genetics, biomarker discovery and early clinical development. Time and space will be provided to drive both pipeline research and explore new biology and pathways for new target discovery. Using state of the art techniques and technologies, the candidate will have the capacity to develop in vitro and in vivo skills to test the involvement of novel pathways and molecules in the pathogenesis of inflammatory diseases and to identify the mechanism of action (MOA) of new targets.
Who You Are
PhD degree in immunology, molecular biology, biochemistry or a related field with a demonstrated record of professional achievement in the form of high-quality publications.
Extensive hands-on experience in cellular and molecular immunology techniques including primary cell isolation from tissues, in vitro immunological assays, multi-dimensional flow cytometry and in vivo animal models.
Independently designing, executing and interpreting experiments.
Have excellent communication skills and willingness to work in a collaborative environment and core lab.
Can present research at intra- and inter-departmental meetings.
Preferred
A strong background in adaptive and innate immunity is highly desirable.
Experience with state-of-the-art precision genome editing technologies and their application for cell engineering is of interest.
Experience with analysis of data from genomic sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics is a plus.
Experience with in vivo immunological experimental techniques
Experience in target discovery within industry research setting
Relocation benefits are available for this posting.
The expected salary range for this position based on the primary location of California is $103,400 to $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Skills Required
- PhD in immunology, molecular biology, biochemistry, or a related field
- Demonstrated professional achievement through high-quality publications
- Extensive hands-on experience with cellular and molecular immunology techniques
- Experience with primary cell isolation from tissues
- Experience with in vitro immunological assays
- Experience with multidimensional flow cytometry
- Experience with in vivo animal models
- Ability to independently design, execute, and interpret experiments
- Excellent communication skills and willingness to work collaboratively
- Ability to present research at intra- and inter-departmental meetings
- Prior industry experience, particularly in target discovery
- Strong background in adaptive and innate immunity
- Experience with precision genome editing technologies and cell engineering
- Experience analyzing genomic sequencing, scRNA-seq, TCR-seq, CITE-seq, or spatial transcriptomics data
- Experience with in vivo immunological experimental techniques
- Experience in target discovery within an industry research setting
Genentech Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.
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Healthcare Strength — Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
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Retirement Support — Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
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Leave & Time Off Breadth — Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.
Genentech Insights
What We Do
Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.






