The Opportunity
The CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech Research and Early Development (gRED) is seeking a highly motivated and well-trained individual to advance drug discovery research and development efforts by executing in vivo experiments in rodent models of cardiometabolic diseases. This position requires working closely with scientists in a multidisciplinary team. Our environment is exciting and fast paced, requiring you to be excellent at multitasking and easily adaptable to meet evolving goals. This is an exciting opportunity to join a growing CVRM biology group and make significant contributions.
Key Responsibilities:
Establish and conduct experiments in relevant rodent models and optimize approaches to model disease processes and states which resemble human diseases
Generate high-quality experimental data to meet strict timelines and project goals.
Communicate key findings at project meetings and make recommendations for follow-up studies and prioritization.
Familiar with relevant scientific literature. Understand and apply relevant scientific knowledge to solving problems arising from the projects involved
Work collaboratively within multidisciplinary project teams
Generate, analyze, and document complex experimental data with a focus on high reproducibility, maintaining accurate Electronic Lab Notebook (ELN) records.
Who You Are
Bachelor’s degree in pharmacology, biology, or related fields with 6+ years of laboratory experience, OR a Master’s degree with 4+ years of experience in industry or academia
A detail-oriented researcher who is passionate about leveraging best disease modeling to accelerate our research and discovery
Hands-on experience with cardiovascular models (myocardial infarction/ischemia–reperfusion, transverse aortic constriction) and their phenotyping (echocardiography, heart catheterization). Proficient survival surgical skills in rodents
Experience with rodent handling, various routes of drug administration (intravenous, intraperitoneal, intramuscular and subcutaneous), non-terminal and terminal blood sampling and tissue harvest.
Strong analytical, organizational and communication skills
Highly motivated, self-driven person, comfortable working independently or as team in a fast-paced environment
Willingness to learn new skills and rapidly adapt to changing priorities for multiple projects.
Preferred
Experience with other cardiometabolic disease models will be a plus.
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of South San Francisco, CA is $85,500 to $158,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Skills Required
- Bachelor’s degree in pharmacology, biology, or a related field with 6 or more years of laboratory experience
- Master’s degree with 4 or more years of experience in industry or academia
- Hands-on experience with cardiovascular models, including myocardial infarction, ischemia-reperfusion, and transverse aortic constriction
- Experience with cardiovascular model phenotyping, including echocardiography and heart catheterization
- Proficient survival surgical skills in rodents
- Experience handling rodents and administering drugs intravenously, intraperitoneally, intramuscularly, and subcutaneously
- Experience with non-terminal and terminal blood sampling and tissue harvest
- Experience with other cardiometabolic disease models
- Strong analytical, organizational, and communication skills
- Ability to work independently and collaboratively in a fast-paced, multidisciplinary environment
- Willingness to learn new skills and adapt to changing priorities
Genentech Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.
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Healthcare Strength — Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
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Retirement Support — Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
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Leave & Time Off Breadth — Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.
Genentech Insights
What We Do
Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.
