Position Summary:
The Research Scientist will work within the Research group to lead projects supporting the development and selection of new indications, with a primary focus on glaucoma. The projects will broaden and refine our understanding of the role of the complement system and additional pathophysiological mechanisms in retinal disease. Ultimately, this knowledge will improve drug development and selection.
Key Responsibilities Include:
- Systematically evaluate and select optimal therapeutic targets within the complement and neurodegenerative pathways.
- Help to establish a reliable screening funnel for candidate optimization and down selection (in vitro, ex vivo, in vivo).
- Manage external vendor relationships and services (i.e. animal CROs, academic collaborators).
- Work with cross-functional team members to achieve project goals (chemistry/manufacturing, pharmacology, bioanalytics, etc.).
- Present data and contribute to scientific discussion within research team and broader organization.
- A portion of the candidate's time will be dedicated contributing to the execution of existing projects.
Education, Registration & Certification:
- Ph.D. in vision research or neuroscience.
- Master's with 5+ years' experience.
Experience:
- 3+ years' experience in ophthalmology research, specifically including diseases of the retina.
- Proven experience in project management and external collaboration.
- Strong people skills and experience working with diverse and geographically disperse associates.
- Excellent verbal and written communication skills.
- Independent individual with high integrity & courage.
- Be a champion of collaboration in high performing teams.
- Highly motivated with the ability to be flexible in a fast-paced environment.
Travel Requirements:
- Expected travel 10% of the time to conferences, external collaboration sites, and occasional home office meetings (Waltham MA)
Benefits and Perks:
Apellis offers a great benefit package which includes: health insurance with full premium coverage, 401K with company match, paid time off (PTO), long- term disability insurance, life insurance and more! Visit https://apellis.com/careers/ to learn more.
Company Background:
Apellis Pharmaceuticals, Inc. is a global biopharmaceutical company that combines courageous science and compassion to develop life-changing therapies for some of the most challenging diseases patients face. We ushered in the first new class of complement medicine in 15 years and now have two approved medicines targeting C3. These include the first and only therapy for geographic atrophy, a leading cause of blindness around the world. With nearly a dozen clinical and pre-clinical programs underway, we believe we have only begun to unlock the potential of targeting C3 across many serious diseases.
For more information, please visit http://apellis.com or follow us on Twitter and LinkedIn
EEO Statement:
Apellis is an equal opportunity employer and complies with all applicable federal, state and local fair employment practices laws. Apellis strictly prohibits and does not tolerate discrimination against employees, applicants or any other covered persons because of race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy), gender (including gender nonconformity and status as a transgender or transsexual individual), age, physical or mental disability, citizenship, past, current or prospective service in the uniformed services, genetic information, marital status, AIDS/HIV status, smoker/nonsmoker, and occupational pneumoconiosis or any other characteristic protected under applicable federal, state or local law.
For San Francisco postings: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
Other Duties:
Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.
What We Do
At Apellis, we are committed to developing transformative therapies for people living with a broad range of debilitating diseases by controlling complement, part of the body’s immune system. Our work is rooted centrally at C3, which is the only target in the complement cascade that addresses all three pathways that can drive disease. Targeting C3 has broad platform potential to treat many diseases where patients have few or no treatment options available. Our programs across ophthalmology, nephrology, hematology, and neurology are further exploring what is possible by targeting C3. For more information, please visit http://apellis.com.
