Senior Research Associate

Posted 5 Days Ago
Be an Early Applicant
8 Locations
Junior
Angel or VC Firm • Software
The Role
The Research Associate will support preclinical drug discovery focused on kidney diseases, managing rodent studies and animal colonies, collaborating with scientists for target validation and therapeutic evaluation, and ensuring compliance with ethical standards in animal care.
Summary Generated by Built In
About Us


We are looking for dedicated professionals who thrive on tackling complex challenges and are committed to improving the lives of patients. If you value innovation, collaboration, and integrity, and are eager to contribute to advancing therapies for renal diseases, we encourage you to join our team. Based in the state-of-the-art Bakar Labs in Berkeley, CA, we are focused on pioneering medicines that make a meaningful impact.


About the Role


We are seeking a highly motivated Research Associate with a strong background in preclinical drug discovery and in vivo research. This individual will join our dynamic team and contribute to advancing our pipeline for kidney diseases. The ideal candidate will play a key role in supporting research efforts, with a focus on rodent studies, animal colony management, and evaluating novel therapeutics in vivo. As programs advance towards in vivo proof of concept, you will collaborate with scientists to support preclinical evaluations using rodent models. You will manage animal colonies, assist with experimental design, and execute hands-on tasks related to in vivo research.

What You'll Do

  • Collaborate with scientists to evaluate novel therapeutic candidates using transgenic mouse models, including target validation and mechanism of action studies.
  • Oversee and maintain mouse colonies, including breeding, genotyping, colony expansion, and accurate inventory tracking of vivarium supplies.
  • Perform routine in vivo tasks, including animal handling, dosing (oral, IV, IP, SC), blood and tissue collection, sample processing, anesthesia administration, and euthanasia.
  • Monitor animal health, maintain compliance with IACUC protocols, and ensure ethical standards in animal care.
  • Contribute to experimental design and execution of in vivo studies to support drug discovery programs.
  • Provide detailed documentation of experimental protocols, observations, and results.
  • Collaborate with multidisciplinary teams, contributing to discussions on in vivo models and study outcomes.
  • Adapt to the evolving needs of the team and contribute to maintaining aggressive project timelines.

What You'll Bring

  • B.S. degree in a relevant scientific field with 2+ years of hands-on experience in preclinical research or a bachelor’s degree with equivalent relevant experience. Industry experience is advantageous but not required.
  • In Vivo Expertise: Proficiency in rodent handling, dosing techniques (e.g., IV, IP, SC), blood and tissue collection, and surgical techniques.
  • Mouse Colony Management: Demonstrated experience in managing transgenic mouse colonies, including breeding, genotyping, and maintenance.
  • Laboratory Skills: Experience with in vivo sample processing and preparation for downstream assays such as histology or molecular analyses.
  • Team Collaboration: Strong interpersonal skills with the ability to work collaboratively in a multidisciplinary environment.
  • Communication Skills: Commitment to reporting activities accurately and in a timely manner; keeping open communication with team members to adapt to a fast-paced environment.
  • Organization: Exceptional attention to detail, organizational skills, record keeping, and the ability to manage multiple tasks efficiently.
  • Commitment to Safety: Adherence to laboratory safety and ethical standards in animal research.
  • Flexibility: Willingness to adapt to team priorities and timelines.

We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.

The Company
HQ: San Francisco, CA
45 Employees
On-site Workplace
Year Founded: 2002

What We Do

5AM was founded in 2002 and pursues investments in advanced life science innovations, and seeks to be diversified across the biopharmaceutical therapeutics, and platform technologies. Within each sector, 5AM invests across multiple therapeutic areas and modalities and evaluates opportunities based on innovative platform technologies, corporate spin-offs and products with shorter development cycles.

Content 5AM shares on this platform is not, and may not be relied on, in any manner, as legal, tax, investment, accounting or other advice or as an offer to sell or a solicitation of an offer to buy an interest in any private fund, special purpose or other investment vehicle sponsored by 5AM Ventures. Content 5AM shares on this platform is not an investment recommendation.

For a full list of all 5AM portfolio companies, please visit: https://5amventures.com/portfolio/

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