AcuraStem is advancing a novel therapeutic approach for amyotrophic lateral sclerosis (ALS) using patient-derived stem cell models. AcuraStem is working to identify new targets and therapeutic approaches employing patient neuronal models in order to find a treatment for ALS. AcuraStem has developed the iNeuroRx platform which utilizes human iPSC derived cells in order to mimic neuromuscular, and neurodegenerative neuron diseases such as ALS. AcuraStem is seeking a research associate to support our iNeuroRx disease modeling platform. This platform will be employed for target discovery/validation, biomarker evaluation and the construction of additional neurodegenerative disease models.
Job DescriptionAt AcuraStem we value scientific excellence, results, persistence, details, teamwork, good decision-making, and continuous learning. We are seeking a research associate who is skilled and well organized in order to drive our research program forward.
The research associate is expected to work in close cooperation with AcuraStem scientists. The incumbent candidate should have experience with mammalian cell culture. The research associate will follow detailed protocols in excruciating detail but also has the ability to propose improvements and changes when necessary.
Responsibilities:
- Maintain cell lines (hiPSCs/HEK/Glia cell) with sterile techniques.
- Performing biochemistry/molecular biology assays.
- Support and collaborate with scientists, labs, vendors and industry experts to ensure completion of tasks/projects.
- Gather, organize and analyze technical information for research study design and for publications and submissions as needed.
- Initiate scientific documents for research, including study reports, protocols, and other related documents.
- B.S. in a biology discipline (Biology, Neuroscience, Bioengineering)
- Experience in mammalian cell culture
- Experience in plasmid DNA preparation, immunostaining, ELISA
- Effective verbal and written communication skills in relating to colleagues and associates both inside and outside the organization
- Demonstrated team player with the ability to work with little supervision.
- Knowledge of EH&S procedures
Additional Information
Scheduling flexibility, which includes late evening, weekend and holiday work hours is required. Due to the demands of maintaining healthy cell cultures, weekend work will be required. Travel may be required to various AcuraStem laboratory sites (~5%).
The candidate must already be in the USA and approved to work immediately.
Skills Required
- B.S. in Biology, Neuroscience, Bioengineering, or related discipline
- Experience in mammalian cell culture (hiPSCs, HEK, glia)
- Experience in plasmid DNA preparation
- Experience in immunostaining
- Experience in ELISA
- Effective verbal and written communication skills
- Demonstrated ability to work as a team player and with little supervision
- Knowledge of Environmental Health & Safety (EH&S) procedures
- Scheduling flexibility including late evenings, weekends, and holidays
- Must be located in the USA and authorized to work immediately
What We Do
AcuraStem is a patient-based biotechnology company dedicated to pioneering the development of treatments for neurodegenerative diseases, specifically amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Utilizing its proprietary iNeuroRx® disease-modeling platform, the company focuses on discovering novel, effective, and broadly acting treatments that address the mechanisms driving these diseases, particularly for sporadic cases where the genetic cause is unknown.
