About Krystal Bio:
At Krystal Biotech, we bring together the brightest and most eager minds to relentlessly pursue the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs.
Founded in 2016, Krystal is distinguished in three powerful ways: science and technology using our patented gene therapy platform, innovative manufacturing supported by our commercial scale facilities, and a unique commercialization model that focuses on the patient’s end-to-end experience.
Krystal received U.S. FDA approval for the first and only redosable gene therapy treatment, VYJUVEK®, for the treatment of Dystrophic Epidermolysis Bullosa (DEB). Krystal continues to leverage our proprietary platform to rapidly advance a robust pipeline of investigational genetic medicines in respiratory, oncology, dermatology, and ophthalmology.
Krystal is headquartered in Pittsburgh, PA, which is home to our two state-of-the-art CGMP manufacturing facilities with teams around the world and satellite offices in Switzerland, Germany, and Japan. We are a company built and run by people who care, are fearless in the face of a challenge, love the work they do, and practice the highest level of scientific integrity. As we grow, we are seeking team members that embody these values.
Job Description Summary:
Krystal Biotech, Inc. is seeking a highly motivated and innovative Research Associate to support multidisciplinary efforts in Upstream Process Development.
The Research Associate will support process development initiatives by conducting experiments related to the characterization and optimization of viral vector production. They will also support the tech transfer of fully characterized processes to the Manufacturing team.
Qualified candidates will demonstrate basic knowledge in fundamental mammalian cell culture techniques. To be successful, this individual will show curiosity, initiative, and the ability to work well in a timeline-driven environment.
The Research Associate role will handle a variety of responsibilities, some of which include:
- Support scientists/senior scientists in the upstream process team for upscaling HSV production
- Perform mammalian cell culture using aseptic techniques
- Prepare buffer and media solutions to support experiments in the lab
- Provide technical support in the lab through equipment optimization projects and troubleshooting, as needed
- Participate in study design and process development brainstorming sessions
- Conduct experiments under defined conditions to verify/reject various types of hypotheses using refined scientific methods
- Record all data and results with accuracy and responsibility
- Ensure that all safety guidelines are always followed strictly and maintain a clean and orderly environment
- Adhere to scientifically-sound practices for experiment documentation, statistically driven data analysis, and interpretation of results
- Interact with cross-functional teams and effectively communicate scientific results
- Other duties as assigned
Requirements and Preferred Qualifications:
- Bachelor’s Degree in Life Sciences or Engineering discipline with relevant industry benchwork experience
- Some understanding in one or more of the following areas: aseptic technique, mammalian cell culture, bioreactor technology, cell biology, and/or virology
- Familiarity with bioreactor operation and upstream process is a plus
- Experience using core scientific techniques
- High capability of multitasking in a fast-paced team-oriented environment
- Excellent oral and written communication skills
Krystal Biotech, Inc. is an Equal Employment Opportunity and Affirmative Action Employers. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. Krystal Biotech, Inc. does not accept unsolicited headhunter and agency resumes. Krystal Biotech, Inc. will not pay fees to any third-party agency or company that does not have a signed agreement with Krystal Biotech, Inc.
What We Do
At Krystal Biotech, Inc., our mission is to make a meaningful difference in the lives of underserved patient populations suffering from debilitating skin diseases. We work to accomplish this goal through scientific innovation and operational excellence, believing that "nature operates in the shortest way possible" (Aristotle).
We are a clinical-stage gene therapy company using our proprietary, engineered virus vector platform to develop effective and innovative treatments for skin diseases. While we are initially developing topical and intradermal "off-the-shelf" novel therapies for rare and orphan dermatological indications, we are expanding the use of our pioneering gene technology to target and treat other rare diseases.
The diseases for which we develop therapies provide inspiration for our day-to-day activities. There is clarity in purpose, a collective empathy driving us forward. Krystal was named after this clarity — a simple realization that we can do better. In doing so, we extend gratitude to the patients, caregivers, advocates and physicians dedicated to the diseases which unite us in purpose.
Community Guidelines: http://bit.ly/KrystalCG
