Join us in developing pioneering therapies that aim to transform the treatment of CKD and change patients’ lives. Our technology is designed to treat diseased kidneys using a patient’s own cells and may prevent or delay dialysis or transplant.
ProKidney’s Bioprocess R&D, Morrisville, NC is seeking a talented, motivated and skilled Research Associate III (on-site) for studies relating to mechanism(s) of action of a cell-based therapeutic and its potency assurance strategy. The individual will be responsible for, and bring proficiency with, performing mammalian cell culture, cell-based assays, qPCR, RNA sequencing, ELISA, Western blot, and generating in vitro data. They will design experiments, record and interpret data, maintain equipment, and assist in ordering lab supplies. The individual must be detail-oriented, have strong communication skills, and be willing to work in a dynamic, fast-paced environment. Independent reading and understanding of the scientific and technical literature for new assay development and troubleshooting is highly desired.
RESPONSIBILITIES
- Perform mammalian cell culture, maintain cell lines, and perform cell-based assays.
- Design and execute qRT-PCR and qPCR protocols.
- Analyze and interpret RNA sequencing data using advanced programs to help guide mechanistic actions.
- Perform Western blot and ELISA-based assays, protein determination, flow cytometry, image based qualitative and quantitative analysis, and other colorimetric assays.
- Record all data and summarize in an organized fashion
- Work with the lab head and other members to design, develop, and execute experiments.
Requirements
Education/Training
BS | MS Degree with 4+ years of relevant experience in academic lab or industry required
Experience
4+ years of cell-based research experience highly preferred
Skills/Abilities
• Basic understanding of, and expertise with molecular biology, cell culture and in vitro assays
• Strong attention to detail.
• Excellent written and oral communication skills.
• Able to effectively use information technology with a proficiency in MS Outlook, Word, Excel and PowerPoint.
• Additional scientific programs a plus.
• Exceptional planning and organizational skills.
• Ability to multi-task and use good judgment when making decisions.
• Demonstrated capability to work as a strong team player and collaboratively
ProKidney is an Equal Opportunity Employer. All applicants are considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. We are committed to the principles of equal employment opportunity for all employees with a work environment free of discrimination and harassment.
What We Do
ProKidney (Nasdaq: PROK), a pioneer in the treatment of CKD through innovations in cellular therapy, was founded in 2015 after a decade of research. ProKidney’s lead product candidate, REACT™ (Renal Autologous Cell Therapy), is a first-of-its-kind, patented disease-modifying autologous cellular therapy with the potential to not only slow and stabilize the progression of CKD, but in some cases potentially drive meaningful improvement in kidney function. Late-stage CKD, Stage 3b - 4, is a key target for REACT™ therapy. REACT™ has received Regenerative Medicine Advanced Therapy (RMAT) designation, as well as FDA and EMA guidance, supporting its ongoing Phase 3 clinical program, which launched in January 2022. For more information, visit www.prokidney.com.
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