Research Associate II

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!  

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. 

Why Join Us? 

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy. 

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth. 

• Global Impact: Contribute to therapies that make a lasting impact on patients globally. 

We are seeking a Research Associate II to join our CMC Process and Analytical Development team. In this role, the Research Associate II will play a key part in supporting the company’s preclinical and clinical programs by executing complex, specialized, and time-sensitive technical cell manipulations and/or analytical assays to characterize and evaluate the functionality of final products under supervision. Additionally, this position will contribute to the development and optimization of processes and assays to advance program objectives. 

FLSA Classification: Hourly, Non-Exempt  
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; On-site  
Reports to: Principal Scientist, CMC Process & Analytical Development  
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477  

What You’ll Do: 

As a Research Associate II, you will play a key role in supporting our CMC PD & AD operations:  

• Perform cell growth and manipulation procedures for the generation of T cell products including, but not limited to cell enrichment, genetic manipulations, cell expansion, drug product formulation and cryopreservation. 

• Assists & performs advanced analytical assays including, but not limited to, flow cytometry, Luminex multiplexing, IncuCyte, and qPCR with limited supervision.  

• Assis/performs accurate and timely documentation of data and transfer to electronic lab notebooks.  

• Assists/performs data analyses e.g., general readouts from common assays, data compilation and presentation preparation.    

• Assists/performs phenotypic and functional characterizations of the products using advanced analytical techniques with limited supervision.    

• Assists/performs vector-associated assays with limited supervision 

• Keeps inventory of reagents/materials up to date 

 Secondary Functions:  

• Ability to clearly communicate and identify problems 

• Basic ability to troubleshoot problems or provide suitable solutions 

• Assists/participates in writing official documents, e.g. Study plans, Research Reports, SOPs. 

• Assists with laboratory organization and cleanliness including reagent & supply management and placing orders.  

• May present scientific results in team or department meetings if desired. 

• Other responsibilities assigned based on business need, skills and capabilities. 

Required Experience and Education: 

• Bachelor’s degree in Biological Science or related field 

• 2+ Years of experience in a biological science-based laboratory research position 

Preferred Experience and Education:  

• Master’s degree in Biological Science or related field.  

• 2+ years of cellular manufacturing and/or process & analytical development, or in a biological science-based laboratory research position 

Competencies:  

• Independent Working: Routine tasks: Limited supervision, Non-standard tasks: Close supervision 

• Communication: Clear & efficient communication, Common courtesy, Interaction mainly limited to own team (peers & supervisor) 

• Problem Solving: Ability to identify, analyze & communicate problems. Basic ability to develop suitable solutions. 

• Critical thinking: Basic reflection on standard processes. Identification of basic need & room for improvement within own/narrow scope 

• Initiative: High degree of initiative & intrinsic motivation to exceed basic expectations (own task & responsibilities) 

• Organizational & Prioritization Skills: Basic organizational skills required to structure own daily tasks according to predefined work packages, schedule & standard lab processes. Prioritization in close interaction with supervisor. 

• Coachability: Receive pre-defined on-the-job trainings essential for area of responsibilities. High responsiveness to constructive criticism & basic ability to autonomously reflect on required improvements & timely implementation of suggested improvements. 

• Leadership Skills, Training & Supervision:   Basic leadership skill required for on-the-job trainings & guidance/support of (new) team members (e.g. providing & receiving feedback, empathy, honesty, reliability). Train, instruct & coordinate E level and train D&C level during onboarding. 

Work Environment:  

• Up to 95% of the Research Associate II’s time will be in the laboratory setting. Laboratory workers are exposed to numerous potential hazards (including flammable liquids, chemical, bloodborne pathogens, and others). wearing lab appropriate general attire (such as long pants and closed-toe shoes), frequent hand washing, no drinking and eating in the lab, and wearing personal protective equipment (PPE), such as lab coats, gloves and safety goggles. Occasional lifting of objects up to 25 lbs is expected.    

• There may be frequent interruptions with moderate noise levels and frequent use of printers, copiers, scanners, computers and other office equipment. Ability to sit, talk, walk, hear and communicate verbally and in writing is required. 

 Travel required: May require limited travel e.g. Occasional off-site events where attendance is preferred. 

Physical demands: 

• Communicating Verbally – expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly. 

• Hearing – the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds. 

• Keyboarding – entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.  

• Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object – usually by holding it in the hands or arms but may occur on the shoulder. 

• Near Visual Acuity – clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).  

• Pushing - Exerting force upon an object so that the object moves away from the object. 

• Pulling - Exerting force upon an object so that the object moves toward the force.  

• Sitting – remaining in a sitting position for at least 50% of the time. 

• Standing/Walking - remain on one's feet in an upright position at a workstation.  

• Stooping – occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles. 

Work authorization/security clearance requirements:  

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment.   

Affirmative Action/EEO statement:   

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, color, religion, national origin, ethnicity, marital status, age, physical or mental disability, medical conditions, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. 

What do we offer?  

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics 

Comprehensive Benefits:  

• Competitive rates for Health, Dental, and Vision Insurance 

• 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment. 

• Sick Time Off – 56 hours  

• 12 Paid Holidays  

• 100% Employer-Paid Life Insurance up to at 1x annual salary, up to 100K ( club together) 

• 100% Employer Paid Short- and Long-Term Disability Coverage  

• 401(k) with Immediate Eligibility  & company match… 

• You are eligible for 401(k) plan participation as of your first paycheck. 

• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment. 

• Partially paid Parental Leave for eligible employees. (3 weeks) 

• Additional voluntary employee paid coverages including  Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.  

Professional Growth:  

• Opportunities to work with leading experts in the field of T-cell immunotherapy.  

• Company provided learning and development opportunities 

• Fast paced, high demand collaborative and dynamic environment.