bit.bio is an award-winning spinout from the University of Cambridge. Our breakthrough technology combines synthetic and stem cell biology for the precise, efficient and consistent reprogramming of human cells used in research, drug discovery, and cell therapy. At bit.bio, we are passionate about engineering human cells that will enable the medicine of the future. To do this we need talented and curious people who want to make an impact on the future of science and therapeutics.
As a team of individuals, we value science, collaboration, openness, curiosity and creativity. We are united by trust and respect for each other.
Location: Babraham Research Campus, Cambridge
Type: Full time, permanent
Start: Immediate / Hours: 40 hrs per week
Lab based position
This role does not meet the minimum salary requirements for UK skilled worker sponsorship. Candidates must already have the right to work in the UK or must not require sponsorship for a Skilled Worker visa.
Your role in our team:
Reporting to the Principal Scientist (AD/QC), the Research Assistant, Quality Control (QC) is responsible for assisting with batch release testing of a wide range of iPSC-derived cell types, together with the optimisation and development of new test methods to improve efficiency and deliver operational excellence.
The Research Assistant, QC will work cross-functionally with teams across bit.bio to help deliver a quality product to market as well as contribute to the continuous development of the QC team, the laboratory environment and overall objectives of bit.bio.
Your key responsibilities will include:
- Perform QC release testing of final product for all cell types in the growing bit.bio ioCells portfolio to ensure our products are of the highest quality standard to meet customer needs.
- Prioritise and manage multiple workflows effectively to ensure consistent output and adherence to expected QC turnaround times.
- Collate and evaluate data generated to ensure QC requirements are met.
- Follow Good Laboratory Practice (GLP) to ensure testing details are fully documented, traceable, accurate, timely, and followed to the highest standards.
- Follow Good Laboratory Practice (GLP) to ensure lab equipment are maintained, and traceable, within documentation.
- Support the optimisation and development of QC release test methods for ioCells and explore opportunities to evaluate new technologies for use in the QC environment, as required.
- Support continuous improvement of QC practices including establishing and improving electronic lab notebook (ELN) templates, supporting data trending, and performing root cause analysis to identify testing issues and appropriate corrective actions.
- Supporting the development and maintenance of key QC Standard Operating Procedures (SOPs) and testing protocols to ensure they remain current and reflective of best practice.
- Support the tech transfer of new cell types entering QC from Product Development including training on new techniques, as required.
You…
- Hold a Bachelor’s or Master’s degree in a relevant field of biological sciences (or equivalent).
- Have practical laboratory experience in human iPSC cell culture (and/or differentiation) and aseptic technique.
- Have practical laboratory experience with molecular biology techniques including qPCR.
- Are detail oriented and experienced in working to SOPs.
- Are a passionate team player with excellent organisational and communication skills.
…and possibly…
- Experience in a QC laboratory and/or working in a cGMP or GLP environment.
- Have practical experience and knowledge of relevant test methods including immunocytochemistry (ICC), flow cytometry and Enzyme-Linked Immunosorbent Assay (ELISA).
- Experience qualifying methods to ICH guidelines.
- Experience of CAPA, LEAN, Six-Sigma, 5S and/or other systems for optimisation and improvement of laboratory processes.
More reasons to join us:
bit.bio provides a vibrant and dynamic work environment in an exciting, fast-moving time for biology. We work with cutting edge technologies and with our world-leading scientific advisory board. We conduct pioneering work with real-world impact.
We trust our people to make significant contributions early on with opportunities to be involved in projects that are key to the success and growth of our young company. We invest in people, creating opportunities for personal development in an inclusive multi-skilled team with ambitious goals that provide opportunities to learn on the job from each other.
Creativity and open minds are encouraged for everyone to contribute to the success of the company.
For information on how we will manage your data please see our Candidate Privacy Notice
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What We Do
bit.bio is an award-winning human synthetic biology enterprise. Our mission is coding cells for health. To do so, we apply the principles of computation to biology. Our current focus is to develop a scalable technology platform capable of producing consistent batches of every human cell. This has the potential to unlock a new generation of medicine: it will enable research and drug discovery to move on from inappropriate models and work with the cells that actually are affected by human disease. A scalable platform of consistent cells will also be the basis for a new generation of cell and tissue therapies. To achieve our goals, we have assembled a team of pioneers in stem cells, cellular reprogramming, mathematical modelling, and cell therapy. Collaboration is at the heart of bit.bio. We are empirical, highly ambitious and driven by a common purpose.
