We advance science so that we all have more time with the people we love.
The Opportunity:
The Downstream Process Development (DSPD) team is seeking a highly motivated Scientist with a specialized focus on filtration processing and relevant biopharmaceutical industry experience. In this role, you will actively participate in advancing multiple innovative downstream process development programs within Roche’s robust pipeline. The successful candidate will drive laboratory execution, contribute to process optimization, and collaborate cross-functionally to support the advancement of breakthrough therapeutics.
Responsibilities:
Experimental Execution: Execute laboratory experiments efficiently according to predefined experimental designs, protocols, and timelines.
Process Optimization: Contribute to the troubleshooting, optimization, and scale-up of downstream processes to successfully meet project milestones.
Documentation & Reporting: Maintain comprehensive, accurate, and highly detailed laboratory records. Ensure timely closure of experiments and author high-quality technical development reports.
Lab Operations: Support the maintenance of essential laboratory equipment and critical raw material inventories to ensure seamless operations.
Collaboration: Partner with team members to ensure DSP laboratories are maintained in a safe, professional, and well-organized manner.
Who You Are:
Ph.D. in Biochemistry, Chemistry, Chemical Engineering, Bioengineering, or a related discipline with 0–4 years of relevant industry experience; OR
M.S. / B.S. in Biochemistry, Chemistry, Chemical Engineering, Bioengineering, or a related discipline with 3–7 years of relevant industry experience.
Core Knowledge: Strong foundational knowledge of downstream process development for biologics (e.g., viral vectors, monoclonal antibodies, vaccines, or recombinant proteins).
Hands-on Experience: Proven experience operating Ultrafiltration/Diafiltration (UF/DF), Tangential Flow Filtration (TFF), and other standard filtration systems.
Preferred Qualifications:
In-depth theoretical and practical understanding of TFF and advanced filtration operations.
Working knowledge and purification skills specific to viral vectors or vaccines.
Familiarity with analytical techniques used for in-process testing and product characterization.
Previous professional experience utilizing data science tools.
The expected salary range for this position based on the primary location of Philadelphia is $91,000 to $169,000 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are not available for this position.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Skills Required
- Ph.D. in Biochemistry, Chemistry, Chemical Engineering, Bioengineering, or related discipline with 0-4 years of relevant industry experience
- M.S. or B.S. in Biochemistry, Chemistry, Chemical Engineering, Bioengineering, or related discipline with 3-7 years of relevant industry experience
- Foundational knowledge of downstream process development for biologics (viral vectors, monoclonal antibodies, vaccines, recombinant proteins)
- Hands-on experience operating Ultrafiltration/Diafiltration (UF/DF) and Tangential Flow Filtration (TFF) systems
- Maintain comprehensive, accurate laboratory records and author technical development reports
- Support maintenance of laboratory equipment and raw material inventories
- In-depth theoretical and practical understanding of TFF and advanced filtration operations
- Working knowledge and purification skills specific to viral vectors or vaccines
- Familiarity with analytical techniques used for in-process testing and product characterization
- Previous professional experience utilizing data science tools
Genentech Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.
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Healthcare Strength — Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
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Retirement Support — Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
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Leave & Time Off Breadth — Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.
Genentech Insights
What We Do
Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.
