Product Manager, Science

Posted 2 Hours Ago
Be an Early Applicant
Hiring Remotely in United States
Remote or Hybrid
144K-189K Annually
Mid level
Healthtech • Biotech
The Role
Own the product vision and roadmap for clinical genomics tools supporting case management, data workflows, clinical review, sign-out, and data delivery. Translate complex clinical and scientific needs into scalable requirements, coordinate lab and engineering stakeholders, and make risk-based tradeoffs while protecting clinical quality, privacy, security, and governance. Use AI to accelerate research, prototyping, and specification development.
Summary Generated by Built In
Who We Are & What We Do 

At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics. 

What is special about this role?

At Helix, we’re focused on improving patient lives, and this role sits at the center of that work. The Product team builds tools that support clinical genomics workflows at Helix. In this role, you’ll shape products for case management, data workflows, clinical review and sign-out, and data delivery. Your work will help lab directors, scientists and engineering teams deliver genomic insights efficiently while protecting clinical quality. 

As a Product Manager, you will:
  • Define the Vision: Set and own product priorities for case management, data workflows, clinical review and sign-out, and data delivery, translating input from clinical users and business partners into a roadmap the team can execute against.
  • Accelerate Innovation: Use AI to build and iterate quickly, from user research to prototypes to specs, giving it clear context so outputs need minimal rework, while reserving your own judgment for strategy and stakeholder alignment.
  • Simplify Complexity: Distill nuanced clinical needs into elegant, scalable product requirements while maintaining a relentless focus on priority.
  • Balance & Scale: Navigate high-stakes tradeoffs to deliver efficiency and scalability without ever compromising on clinical quality.
  • Unify Teams: Act as the bridge between lab directors, scientists, and global engineering teams to ensure seamless product releases.
  • Guardian of Trust: Oversee the health of your product area, including data privacy, security, and governance within our AI-driven solutions.
 
About you:
  • Educational Foundation: B.S. or M.S. in Biology, Engineering, or a related technical field.
  • Domain Expertise: Deep experience or knowledge of clinical genomics and variant interpretation; you understand the science behind the software.
  • Proven PM Track Record: 3+ years of software product management experience in a biotech laboratory, ideally within a clinical setting.
  • AI Fluency: Comfortable building AI tools and applying critical judgment to what they output and when AI-driven automation is worth building to drive efficiency, all while keeping product integrity, user needs, business goals, and privacy or regulatory requirements in mind.
  • Clarity & Collaboration: Exceptional communication skills with a natural ability to translate complex technical/biological nuances into clear, actionable product needs.
  • Execution Mindset: Highly organized and reliable. You thrive in ever-changing environments and have the backbone to make high-stakes, risk-based tradeoff decisions.

Pluses:
  • CLIA/CAP and/or medical device experience.
  • Some familiarity with SQL and relational databases, some simple programming abilities with any language.

Expected Interview Process:
1) Recruiter Screen 2) Manager Screen/Tech Screen 3) Onsite 4) Offer 

Expected Pay For This Role:
There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity 
  • Expected Helix Base: $144,000 - $189,000
  • Expected Helix Discretionary Annual Bonus: 10% of your annual salary
  • Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
  • Comprehensive Health Insurance with Date of Hire eligibility 
    • Above average employer paid premium coverage 
  • 12 weeks Helix Paid Parental Leave option 
  • 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
  • Comprehensive Well-Being Benefits 
  • Flexible PTO
  • Remote options for many roles and a home office stipend 

What To Expect During Your First 90 days:
  • First 30 days: you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.
  • Day 30 - 60: you’ll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities. 
  • Day 60 - 90: you’ll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.

To learn how Helix collects, uses, and protects your personal information during the recruitment process, please review our Privacy Notice.

Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.

 #LI-Remote
Compensation
The base pay range for this role is $144,000 – $189,000 per year.

Skills Required

  • Bachelor's or master's degree in Biology, Engineering, or a related technical field
  • Deep experience or knowledge of clinical genomics and variant interpretation
  • At least 3 years of software product management experience in a biotech laboratory, ideally in a clinical setting
  • Experience building AI tools and evaluating AI-driven automation
  • Exceptional communication skills and ability to translate complex technical and biological concepts into product requirements
  • Strong organization, reliability, and ability to make high-stakes, risk-based tradeoff decisions
  • CLIA/CAP experience
  • Medical device experience
  • Familiarity with SQL and relational databases
  • Simple programming ability in any language

Helix Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Helix and has not been reviewed or approved by Helix.

  • Leave & Time Off Breadth — Feedback suggests generous PTO, flexible time away, unlimited vacation, paid sick days, and paid parental leave support work–life balance. These policies are frequently highlighted alongside flexible scheduling.
  • Healthcare Strength — Feedback suggests medical, dental, and vision coverage are complemented by a wellness program. Access to health-focused initiatives contributes to a comprehensive core benefits package.
  • Wellbeing & Lifestyle Benefits — Feedback suggests commuter benefits, free daily meals, and onsite parking enhance day‑to‑day experience. Such perks, combined with flexible work arrangements, add lifestyle value beyond base pay.

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The Company
HQ: San Mateo, CA
200 Employees
Year Founded: 2015

What We Do

Helix is a rapidly growing startup focused on personal genomics. Helix has a simple but powerful mission: to empower every person to improve their life through DNA. We’re creating an ecosystem where people can explore diverse and uniquely personalized applications provided by high-quality partners.

Why Work With Us

We are collaborators—scientists, engineers, designers, marketers, and more—working across four offices to solve complex challenges locked within the human genome. We are biased toward action as we strive to uphold integrity in sequencing, science, and communication. At Helix, transparency, collaboration, and empowerment drive us in all that we do.

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