Principal Project Manager

Welcome to Holly Springs, North Carolina— home to Roche/Genentech's largest-ever investment: a $2B greenfield start-up where next-generation technology, high-performing teams and Operational Excellence converge to create the global standard for high-volume, highly-efficient Drug Product manufacturing. 

The facility's core is defined by Innovation - leveraging advanced automation, robotics, digital tools, real-time data analytics, and simple, streamlined processes to produce the highest quality medicines. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes.  This is a fast-paced, entrepreneurial environment with a high-level of accountability, with planned launch in 2028. 

Are you a problem-solver and change-agent who thrives in a Team environment, eager to tackle the most complex manufacturing challenges? If so, this is a once-in-a-lifetime opportunity to launch a state-of-the-art facility from the ground-up and shape the culture of our organization for the next generation. 

Join us in Holly Springs, where you won't just build a plant—you will build the future of medicine.

The Opportunity:

Please note there are multiple positions available.

The Principal Project Manager role in the Holly Springs Program Management Office (PMO) leads the planning and execution of site wide projects and programs from initiation through delivery and value generation. Organizes cross-functional activities, leads matrixed team, ensuring completion of the project while adhering to budget, scope and schedule requirements. Role will build tools and establish project controls and governance to effectively manage highly complex project delivery. 

In this exciting role, in the initial Green Field phase of site ramp up, you will directly lead the operational readiness, New Product Launch, Tech Transfer and ramp-up of major elements of the DP site while establishing the Project Management discipline and tools at site. Once operational, you will manage projects related to the reliable supply and enhanced performance of the site, as well as new capabilities and technologies we are strategically planning for. You will act as a primary point of contact for project portfolio strategy. 

• You will enable delivery of key site portfolio projects and programs. Ensure accurate project scoping to enable accurate identification of resources, timeline, and budget. Manage projects to allow for the maintenance of identified scope, timeline, and budget, ensuring the realization of the project benefit to the site. 

• You will understand and support the balance of priorities and dependencies within the portfolio by continuously assessing the health of projects in scope as they progress, proactively identifying and making adjustments as needed to ensure the projects adherence to scope, cost, schedule and successful realization of benefit to the site.

• You will adhere to and support development of best practices and guidance related to site project management and delivery to ensure effective project planning and execution, across a wide variety of business projects (e.g. CAPEX, sustainability, refurbishment, innovation, etc.) 

• You will collaborate effectively with site functional teams, along with applicable partners and stakeholders in Pharma Technical (PT) functions, Roche PTT & PTY functions, and Roche Corporate groups (Supply Chain, Development), to ensure alignment and progression to successful delivery of projects in scope.

• You will act in a lead capacity on cross functional strategic activities including leading assessments, meetings & workshops, developing deliverables, providing guidance and direction to team members, and delivering support. 

• You will use your excellent team building and communication skills with the ability to listen and respond with agility and resilience in a fast paced industrial setting.

Who you are:

• You have a Bachelor's Degree or above, preferably in Engineering (Automation, Electrical, Chemical, Civil, Facilities, Mechanical, Process, or Industrial), related Science field, Supply Chain Management, or related field. 

• You have at least 7 years of successful experience in the Biotech/Pharmaceutical industry, particularly related to project/portfolio management and execution, large scale project management, Tech transfer and/or New Product Introduction experience.

• You have experience in scoping, planning, and leading cross-functional project teams’ execution of diverse projects, with a wide range of levels of complexity, technical and/or business related.

Preferred Qualifications:

• You have a graduate degree or certification in Project Management (i.e. PMI certification) are highly desirable. 

• You have exceptional influencing capabilities, interpersonal and broad communication skills, negotiation, collaboration, and strategic consulting skills. Excellent time management and organizational skills.

• You have a demonstrated ability to lead with and without functional direct-line authority, effectively engaging key Stakeholders. 

• You have a strong understanding of basic principles of several engineering disciplines. Understanding of key items such as project risks and integration implications, understanding facility end-user operational needs and principals, acting as an advocate in helping Site and facility end-users develop, and establishing functional organization.

• You understand and advocate for Safety, Quality, Delivery, Engagement, and Cost to assure that the project meets or exceeds all corporate guidelines. 

• You have experience in an FDA regulated industry, hospital, or clean room environment. 

The expected salary range for this position based on the primary location for this position of Hillsboro, OR is $118,000 - $219,000 . Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

This position is eligible for relocation benefits

Link to Roche/Genentech Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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