As a Principal Machine Learning Engineer focused on Clinical Trial Forecasting and Optimization, you will be an integral part of our Quantitative Sciences Development team, dedicated to transforming patient lives through advanced disease research. Your role involves leveraging applied machine learning to develop innovative tools and methodologies, improving data-driven decision-making for clinical operations. You will lead projects that enhance Biogen's capacity to bring products to market efficiently, working closely with cross-functional teams. This position is pivotal in driving our strategic vision to establish Biogen as a leader in neuroscience, neurology, immunology, and rare diseases. Your contributions will directly influence our corporate vision and strategy, helping to advance research and patient empowerment while fitting seamlessly into our collaborative environment.
What You’ll Do:
· Design, develop, and implement complex machine learning pipelines for clinical trial forecasting and optimization.
· Engineer forecasting models and features to enhance clinical operations.
· Conduct technical, analytical, and performance validation analysis using CI/CD and MLOps pipelines.
· Review code and code artifacts to ensure high-quality algorithmic designs compliant with industry standards.
· Integrate and develop novel sensor-based measurement solutions.
· Improve tools and applications for clinical operations forecasting.
· Serve as a key stakeholder and subject matter expert in internal and external alliances.
· Collaborate with diverse teams to advance clinical trial optimization strategies.
Who You Are: You possess a deep passion for advancing human disease understanding through digital technologies. Your intrinsic motivation drives you to solve complex problems, offering innovative perspectives and exercising sound judgment. You thrive in collaborative environments, effectively communicating and building consensus across diverse teams. Your expertise in data science and machine learning, coupled with your ability to manage interdisciplinary projects, positions you as a valuable asset to our organization.
Required Skills:
· PhD in biomechanical engineering, data science, bioinformatics, computer science, or applied mathematics; or Master’s degree with additional experience.
· At least 5 years of experience in Pharma/Biotech/Tech industry or significant academic/clinical experience.
· Expertise in data visualization, application development with machine learning endpoints, and user experience design.
· Proficiency in programming with Python and relevant libraries (numpy, pandas, scipy, statsmodels, scikit-learn, TensorFlow, matplotlib, Plotly).
· Experience managing complex interdisciplinary research and development projects.
Preferred Skills:
· Strong background in temporal forecasting methodologies.
· Experience in building consensus within technology and business teams.
· Familiarity with emerging technologies in clinical trials.
Additional Information
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
Skills Required
- PhD in biomechanical engineering, data science, bioinformatics, computer science, or applied mathematics; or Master's degree with additional experience
- At least 5 years of experience in Pharma/Biotech/Tech industry or significant academic/clinical experience
- Expertise in data visualization, application development with machine learning endpoints, and user experience design
- Proficiency in programming with Python and relevant libraries
- Experience managing complex interdisciplinary research and development projects
Biogen Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Biogen and has not been reviewed or approved by Biogen.
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Fair & Transparent Compensation — Pay is generally positioned as competitive and often perceived as fair across roles, with total compensation framed as strong when bonus and equity are included. Compensation sentiment is described as above-average overall, though it varies by function and business cycle.
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Equity Value & Accessibility — Equity programs are repeatedly highlighted as a meaningful part of the total package, including stock programs and an employee stock purchase plan. Equity and bonus elements are portrayed as important contributors to feeling well rewarded beyond base pay.
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Leave & Time Off Breadth — Time-off benefits are described as distinctive, including a year-end shutdown and a paid sabbatical after extended tenure. Vacation, holidays, sick time, and personal-significance days are also presented as supportive of work-life needs.
Biogen Insights
What We Do
Through cutting-edge science and medicine, Biogen discovers, develops and delivers innovative therapies worldwide for people living with serious neurological and neurodegenerative diseases. Founded in 1978, Biogen is a pioneer in biotechnology and today the Company has the leading portfolio of medicines to treat multiple sclerosis, has introduced the first and only approved treatment for spinal muscular atrophy, and is at the forefront of neurology research for conditions including Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. Biogen also manufactures and commercializes biosimilars of advanced biologics. With approximately 7000 people worldwide, we are truly a global organization, headquartered in Cambridge, Massachusetts, which is also home to our research operations. Our international headquarters are based in Zug, Switzerland and we have world-class manufacturing facilities in North Carolina and Denmark. We offer therapies globally through direct affiliate presence in 30 countries and a network of distribution partners in over 50 additional countries. For more information, please visit www.biogen.com. Follow us on social media – Twitter, LinkedIn, Facebook, YouTube.
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