Cellares is building a next-generation Integrated Digital Manufacturing Operations (IDMO) platform to enable scalable, GMP-compliant cell therapy manufacturing. As part of this transformation, we are establishing a modern enterprise data foundation powered by Databricks to unify data across engineering, manufacturing, quality, supply chain, finance and commercial systems.
We are seeking a Principal Enterprise Data Architect, a highly hands-on individual contributor who will design, build, and operationalize our enterprise data platform from the ground up.
This is a multidisciplinary role and this individual will play a critical role in enabling real-time decision-making, data governance, and AI readiness across the enterprise. This role is a startup-style builder (90% hands-on) and will evolve into a foundational leader for scaling data capabilities, including alignment with our Global Capability Center (GCC).
Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.
Responsibilities
- Architect and implement Databricks Lakehouse architecture
- Build end-to-end ETL/ELT pipelines
- Define canonical data models and scalable patterns
- Integrate SAP S/4HANA, Tulip MES, LabVantage LIMS, Salesforce, and engineering systems
- Align with API-first/event-driven architecture (MuleSoft / Workato)
- Define data glossary, lineage, and quality frameworks
- Implement Unity Catalog and governance aligned to GMP/21 CFR Part 11
- Prepare datasets for analytics and AI/ML use cases
- Support structured and unstructured data processing
- Evaluate and implement BI tools (Sigma, Looker, Tableau)
- Enable self-service analytics with governance
- Build pipelines using Python, SQL, Spark
- Establish reusable frameworks
- Partner with engineering, manufacturing, quality, finance and software teams
- Translate business needs into data solutions
Requirements
- Bachelor’s or Master’s degree in Engineering, Life Sciences, Information Systems, or related field
- 10+ years in data architecture/data engineering
- Strong Databricks/Spark experience
- Experience building data platforms from scratch
- Integration with ERP/MES/LIMS/CRM systems
- Azure cloud experience
- Self-awareness, integrity, authenticity, and a growth/entrepreneurial mindset
Top Skills
What We Do
Cellares is revolutionizing cell therapy manufacturing. We are developing a one-of-a-kind solution, The Cell Shuttle, to overcome the challenges associated with manufacturing so these life-saving therapies are affordable and widely available to patients who can benefit. The clinical impact of cell therapy in treating cancer has been proven, but this therapeutic approach has several limitations, especially in manufacturing, leaving extremely sick patients waiting for treatment and desperate for hope. Since cell therapy is currently produced for a single patient at a time, it is expensive to manufacture, requiring significant time and resources, and is difficult to scale. Preclinical and clinical scientists, as well as commercial cell therapy manufacturers also lack the options to fully automate their manufacturing process quickly, safely, cost-effectively and at the scale they need. The Cell Shuttle is an automated and closed end-to-end manufacturing solution that is flexible and scalable, enabling customers to run exact processes specified for their cell therapy. Compared with the current manual manufacturing processes for cell therapy, the Cell Shuttle’s next-generation automated manufacturing solution has 10 times the scalability (meaning 10 times more patient doses can be produced simultaneously), enables a three-fold reduction in process failure rates and will reduce the per-patient manufacturing cost by up to 70 percent for most processes.
