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Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information.
Job Description
Brief Description:
The Principal, Cloud Software Engineer will be responsible for designing, developing, and maintaining modern healthcare-focused applications that support clinical, research, and enterprise RnD AAAI initiatives across the RnD organization. This role will lead the development of secure, scalable, AI-enabled web applications and APIs within an AWS cloud environment, with a strong emphasis on product development, user experience, and delivery of intelligent software solutions.
Essential Functions
Design, develop, and maintain full stack web applications using Python, Java, C++ and modern frontend frameworks.
Build scalable backend services and APIs using Python frameworks such as FastAPI, Flask, or Django.
Develop responsive, intuitive, and secure user interfaces using React, TypeScript, JavaScript, HTML5, CSS and Tailwind.
Build healthcare and research applications that support clinical, operational, and AI-enabled workflows.
Collaborate with Product, AI/ML/Data Engineering, IT / Infrastructure and Business teams to translate requirements into effective software solutions.
Design and develop application features that incorporate AI/ML capabilities.
Integrate AI services and machine learning models into production applications through APIs and service interfaces.
Work with AI/ML teams to support model inference, prompt-based experiences, and AI-powered workflows in healthcare use cases.
Build secure and scalable application components within the AWS environment using services such as EC2, Lambda, ECS/EKS, API Gateway, S3, CloudFront, CloudWatch, and IAM.
Implement authentication, authorization, role-based access, and secure data handling patterns appropriate for regulated healthcare environments.
Develop integrations with internal and external systems using APIs, event-driven patterns, and secure service communication.
Create and maintain automated unit, integration, and end-to-end tests to ensure software quality and reliability.
Support CI/CD practices and modern software delivery workflows using tools such as GitHub Actions, Jenkins, or AWS CodePipeline.
Contribute to application monitoring, logging, and troubleshooting to ensure performance, stability, and maintainability.
Participate in architecture and design reviews, providing input on application structure, scalability, security, and AI integration patterns.
Document application behavior, technical designs, and operational procedures.
Ensure solutions align with healthcare privacy, security, and regulatory expectations including HIPAA, GDPR, and GxP-aligned practices where applicable.
Mentor other engineers and contribute to engineering standards, code quality, and technical best practices.
Required Knowledge, Skills and Abilities
Strong proficiency in Python, Java, C++ development with experience building enterprise or healthcare software applications.
Strong experience with modern frontend frameworks such as React, Angular, or Vue.js.
Experience designing and developing REST APIs and application backends.
Strong understanding of AWS services used for application development and deployment.
Experience building secure, scalable web applications in cloud environments.
Experience with authentication, authorization, and secure application design patterns.
Strong understanding of application testing practices, including unit, integration, and end-to-end testing.
Experience integrating third-party services, APIs, and internal systems.
Experience developing applications that incorporate AI/ML capabilities or intelligent workflows.
Familiarity with AI/ML application patterns such as model inference, LLM integration, prompt-driven experiences, search/retrieval, summarization, or recommendation features.
Experience working with Data Science or ML teams to productionize AI-driven application features.
Knowledge of healthcare privacy, security, and regulatory requirements, including HIPAA and GDPR.
Strong analytical, troubleshooting, and problem-solving abilities.
Excellent communication skills and ability to work effectively with cross-functional stakeholders.
Experience working in Agile/Scrum development environments.
Preferred Knowledge, Skills and Abilities
Experience in Healthcare, Life Sciences, Pharmaceutical, Biotechnology, Clinical Research, or Medical Device environments.
Experience building AI-enabled healthcare applications, clinical decision support tools, or intelligent workflow solutions.
Experience developing event-driven or service-oriented application architectures.
Knowledge of software architecture patterns and enterprise integration practices.
Familiarity with regulated software development, validation, documentation, and change control practices.
Required/Preferred Education
Preferred Bachelor’s degree in Computer Science, Software Engineering, Information Technology, Data Science, Bioinformatics, Mathematics, or a related technical discipline required.
5+ years of professional software engineering experience.
3+ years of experience designing and deploying cloud-native applications within AWS environments.
Demonstrated experience delivering complex software projects from design through production support.
Description of Physical Demands
Occasional mobility within office environment
Routinely sitting for extended periods of time
Constantly operating a computer, printer, telephone and other similar office machinery
#LI-DM1
Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.
The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits
Skills Required
- Strong proficiency in Python, Java, and C++ development
- Experience with modern frontend frameworks (React, Angular, or Vue.js) and TypeScript/JavaScript
- Designing and developing REST APIs and backend services
- 3+ years designing and deploying cloud-native applications within AWS (EC2, Lambda, ECS/EKS, API Gateway, S3, CloudFront, CloudWatch, IAM)
- Experience building secure, scalable web applications and implementing authentication/authorization and secure data handling patterns
- Experience with application testing practices (unit, integration, end-to-end)
- Experience integrating third-party services and internal systems via APIs and event-driven patterns
- Experience developing applications that incorporate AI/ML capabilities and working with ML/DS teams to productionize models
- Familiarity with AI/ML application patterns (model inference, LLM integration, prompt-driven experiences, search/retrieval, summarization)
- Experience with CI/CD and delivery workflows (GitHub Actions, Jenkins, AWS CodePipeline)
- Knowledge of healthcare privacy, security, and regulatory requirements including HIPAA and GDPR (GxP-aligned practices where applicable)
- Preferred Bachelor's degree in Computer Science, Software Engineering, Information Technology, Data Science, Bioinformatics, Mathematics, or related technical discipline
- 5+ years of professional software engineering experience
- Demonstrated experience delivering complex software projects from design through production support
- Experience working in Agile/Scrum development environments
- Experience in Healthcare, Life Sciences, Pharmaceutical, Biotechnology, Clinical Research, or Medical Device environments
- Experience building AI-enabled healthcare applications, clinical decision support tools, or intelligent workflow solutions
- Experience developing event-driven or service-oriented application architectures
- Familiarity with regulated software development, validation, documentation, and change control practices
Jazz Pharmaceuticals, Inc Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Jazz Pharmaceuticals, Inc and has not been reviewed or approved by Jazz Pharmaceuticals, Inc.
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Fair & Transparent Compensation — Fair & Transparent Compensation: Pay is considered competitive to strong versus biopharma peers, reinforced by market-competitive ranges in public postings. Company materials emphasize a robust total-rewards mix of base, bonus, and equity.
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Parental & Family Support — Parental & Family Support: Global paid child-bonding leave for all parents and paid caregiver leave are explicitly offered. Additional paid time elements like bereavement and a Global Volunteer Day expand family and life-event support.
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Wellbeing & Lifestyle Benefits — Wellbeing & Lifestyle Benefits: A market-leading mental-health program provides extensive counseling and coaching access via Lyra. A Wellbeing Reimbursement Account and wellness resources broaden everyday lifestyle support.
Jazz Pharmaceuticals, Inc Insights
What We Do
Jazz Pharmaceuticals plc (Nasdaq: JAZZ), is a global biopharmaceutical company whose purpose is to innovate to transform the lives of patients and their families. We are focused on developing life-changing medicines for people with serious diseases—often with limited or no options—so they can live their lives more fully. By transforming biopharmaceutical discoveries into novel medicines, we are working to give people around the world the opportunity to redefine what’s possible – to make the “small wins” big again. Founded in 2003 and headquartered in Dublin, Ireland, Jazz Pharmaceuticals has a significant corporate presence in Palo Alto, CA, Philadelphia, PA and Oxford, England, with manufacturing facilities in Ireland and Italy. We maintain a highly collaborative culture where employees focus on how they can be successful and accomplish positive results by exemplifying the company’s core values: integrity, collaboration, passion, innovation and the pursuit of excellence. Together, we are more than 3,100 experts, analysts, specialists, advocates, scientists and professionals all with diverse backgrounds and perspectives. Working together, we are proud to support patients, innovate and bring new medicines to market. For more information, please see our website at www.jazzpharma.com and follow us on Twitter at @JazzPharma. For information on fraudulent schemes involving our company name and recruitment, please visit https://bit.ly/2J1EjMA. For guidelines on engaging with Jazz on social media, please visit https://bit.ly/2OaMOuq.
