Manager, Data Science

Posted 2 Days Ago
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San Carlos, CA, USA
In-Office
150K-188K Annually
Senior level
Biotech
The Role
Leads and develops a data science team supporting R&D Operations. Owns the data science roadmap, sample governance, data processes, and operational workflows. Directs machine learning, AI, forecasting, optimization, and data product development from prototype through production. Establishes governance, SOPs, data integrity, and reproducibility practices while partnering with engineering, analytics, and R&D stakeholders to improve efficiency, turnaround time, and cost.
Summary Generated by Built In

POSITION SUMMARY:

Natera is a global leader in cell-free DNA testing, advancing diagnostics in oncology, women’s health, and organ health to support better patient care. As a Data Science Manager in R&D Operations, you will lead a team of data scientists to design and implement data solutions to accelerate R&D at Natera. You will take ownership of operational data workflows, establish scalable processes and SOPs, and apply ML and/or AI expertise to enable informed decision-making and drive efficiency. You will work closely with our Data Engineering Manager and Data Analytics Manager to deliver integrated, reliable data solutions across the team.

RESPONSIBILITIES:

  • Direct, mentor, and develop a team of data scientists, including hiring, performance management, and career development
  • Set the technical direction for the data science team and advance its ML/AI capabilities
  • Own the data science roadmap for R&D Operations, define success metrics, and report progress and status to R&D Operations and executive stakeholders
  • Translate pain points and opportunities surfaced by data analytics into solutions–process changes, algorithms, or new tools–and drive their implementation to deliver measurable process improvement, championing efficiency gains in turnaround time and cost per activity across R&D Operations
  • Own the sample governance process end-to-end, ensuring accuracy, timeliness, and accountability, and manage the associated stakeholder relationships
  • Develop and oversee machine learning models, optimization strategies, and AI solutions to forecast demand, optimize resource allocation, and automate operational processes
  • Lead the development of new data products, as well as the training and enablement around them to grow visibility, self-service, and data-driven decision-making across R&D Operations
  • Design, document, and implement processes for data governance, data integrity, and reproducibility across R&D Operations
  • Partner with the Data Engineering and Data Analytics Managers and collaborate cross-functionally across R&D and supporting functions to translate business needs into governed, reliable data solutions
  • Write clear, testable requirements (e.g. acceptance criteria, data contracts) and define the path from prototype to production in partnership with Data Engineering

QUALIFICATIONS:

  • 7+ years of experience in data science in biotechnology, life sciences, or operations research
  • Demonstrated people-management experience, including hiring, mentoring, and developing data scientists through coaching on performance and career growth
  • Experience owning a data science roadmap and communicating progress to senior and executive stakeholders
  • Working knowledge of a relevant scientific or operational domain–biology or life sciences strongly preferred, operations research a close second–sufficient to partner effectively with R&D Operations stakeholders
  • Experience working with laboratory or operational data (e.g., laboratory informatics management system (LIMS), sample management, inventory, purchasing/procurement, or equipment operations)
  • Track record of driving process improvement–identifying root causes and delivering solutions through process changes, algorithms, or new tools
  • Strong background in building data processes, SOPs, and governance frameworks
  • Expertise in Python (including pandas, scikit-learn, TensorFlow/PyTorch) and SQL
  • Hands-on expertise in machine learning and/or AI applied to real-world problems, setting technical direction for predictive modeling and optimization solutions
  • Experience taking ML models or data products from prototype to production, including monitoring and maintenance
  • Experience with modern cloud data warehouse and transformation tooling (e.g. Snowflake, dbt)
  • Experience partnering with peer functions such as engineering and analytics to deliver end-to-end solutions, including writing requirements or technical specifications
  • Clear, direct communication skills to translate complex data insights into actionable business recommendations
  • Strong critical thinking and a drive for learning and problem-solving

Nice to Have

  • Advanced degree in biology, molecular biology, biochemistry, bioinformatics, or operations research
  • Familiarity with data integrity and audit-readiness practices in a regulated (GxP/GCLP) environment

Compensation & Total Rewards 

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of  hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

  • Annual performance incentive bonus

  • Long-term equity awards

  • Comprehensive health benefits (medical, dental, vision)

  • 401(k) with company match

  • Generous paid time off and company holidays

  • Additional wellness and work-life benefits

Compensation Range
$150,100—$187,600 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. 

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams 
- FBI Cyber Crime resource page 

Skills Required

  • 7+ years of experience in data science in biotechnology, life sciences, or operations research
  • People-management experience, including hiring, mentoring, and developing data scientists
  • Experience owning a data science roadmap and communicating with senior and executive stakeholders
  • Working knowledge of biology, life sciences, or operations research
  • Experience with laboratory or operational data, such as LIMS, sample management, inventory, procurement, or equipment operations
  • Track record of driving process improvement through process changes, algorithms, or new tools
  • Experience building data processes, SOPs, and governance frameworks
  • Expertise in Python, pandas, scikit-learn, TensorFlow or PyTorch, and SQL
  • Hands-on expertise in machine learning or AI applied to real-world problems
  • Experience taking machine learning models or data products from prototype to production, including monitoring and maintenance
  • Experience with modern cloud data warehouses and transformation tooling, such as Snowflake and dbt
  • Experience partnering with engineering and analytics functions to deliver end-to-end solutions and technical specifications
  • Clear, direct communication skills for translating data insights into business recommendations
  • Strong critical thinking, learning, and problem-solving skills
  • Advanced degree in biology, molecular biology, biochemistry, bioinformatics, or operations research
  • Familiarity with data integrity and audit-readiness practices in a regulated GxP or GCLP environment

Natera Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Natera and has not been reviewed or approved by Natera.

  • Healthcare Strength — Medical plan choice, fertility support, and free Natera tests for employees and families are emphasized alongside dental, vision, and life/disability coverage. These elements indicate robust core health coverage.
  • Equity Value & Accessibility — An Employee Stock Purchase Plan is available, and equity is described as a significant part of compensation in some roles. This accessibility to ownership can meaningfully augment overall pay.
  • Leave & Time Off Breadth — A flexible, no‑accrual PTO policy and parental leave are positioned as part of the package. This breadth suggests meaningful time‑off provisions are included.

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The Company
HQ: Austin, TX
6,000 Employees
Year Founded: 2004

What We Do

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. Where some set out to build a test, we set out to achieve a mission: change the management of disease worldwide by using DNA testing to proactively inform treatment. Through a cfDNA technology platform approach, we've pioneered noninvasive testing in unlimited applications—each with their own potential to revolutionize care for patients. #TeamNatera includes clinicians, scientists, biostatisticians, researchers, and laboratory professionals from around the world. Our diverse teams blend a passion for patients with deep clinical, scientific, and technological roots. Natera’s tests are validated by more than 100 peer-reviewed publications that demonstrate high accuracy.

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