The Opportunity
The ITOT Infrastructure position offers a unique opportunity to shape the information and technology solutions in alignment with Pharma Manufacturing. Reporting to the ITOT System Operations and Infrastructure Lead, you will be a member of the ITOT Manufacturing Network and deliver Globally harmonized IT and OT solutions for the global PT network.
As IT OT Infrastructure Engineer, you will be responsible for the local Manufacturing Infrastructure and act as the key contact for the Global IT Teams delivering and operating the Global Infrastructure. In partnering with the site your focus is always on Manufacturing Production Make Assess Release (MAR) in alignment with site priorities as well as demand originating from Projects.
Key Responsibilities:
Manage ITOT Infrastructure for Manufacturing System Platforms including IMS, MES , DCS, SCADA and other Control Systems.
Site ITOT Infrastructure Support Coordinator with Global Infrastructure solutions at site (e.g. support of Active Directory and firewall policies to allow proper access and communication).
Lead and/or provide support for the evaluation, installation, and maintenance of Manufacturing infrastructure including installation and upgrade of control systems hardware, software, control networks, user administration, database administration, security, system monitoring, backup and recovery of Microsoft Windows Server Operating Systems and SQL Databases.
Implement Robust Disaster Recovery Solutions.
Lead and/or support implementation of ITOT infrastructure standards and best practices across all Site ITOT and Process Automation platforms, working with other process automation engineers, IT and OT professionals.
Support commissioning and startup activity of new process control systems and manufacturing systems (Syncade (will be replaced with PharmaSuite) , DeltaV, OSI PI historian, etc).
Be the go to Infrastructure expert at the site who bridges the gap between Automation and underlying Storage Compute and Network infrastructure.
Execute control system virtualization administration, user administration, system monitoring, capacity planning, design, installation, configuration, and upgrade of platform.
Execute computer system validation and control system lifecycle management.
Support the integration of Edge Computing and IIoT gateways to facilitate real-time data flow to the OSI PI Historian and cloud-based analytics.
Partner with the Cyber Security Engineer to implement Zero Trust architectures and robust security measures.
Support data backup, recovery management, and disaster recovery plans and exercise on manufacturing infrastructure.
Triage, troubleshoot, and resolve ServiceNow Trouble Ticket Incident, Requests, and Problems associated with manufacturing infrastructure.
Who You Are
Bachelor’s degree in Engineering, Computer Science, or equivalent experience.
A minimum of 7 years systems engineer experience involved in the design, implementation, and/or support of automation systems, preferably in a regulated (Pharmaceutical) industry.
24X7 environment, participate in an on-call environment to meet business continuity requirements, including weekends and holidays as required.
Strong understanding and experience working with OT Manufacturing Infrastructure, security management, Automation Control Systems, and data backup technologies.
Experience working in a change control environment, computer systems validation, and Good Manufacturing Practice (GMP) documentation.
Experience with various Operating Systems, Storage, Backup, Application and Infrastructure Monitoring, Virtualization, LAN/WAN, Firewalls, RDBMS, Client-server and terminal virtualization as a System Administrator.
Advanced expertise in VMware or Nutanix for managing virtualized control system workloads.
Experience with Composable Infrastructure, Next Gen Antivirus EDR/XDR technologies, and Composable Infrastructure.
Experience with High Availability (HA) Failover Clustering and Redundancy.
Experience with Microsoft SQL Server installation, troubleshooting, and tuning.
Experience with Microsoft Active Directory and group policy configuration.
Familiarity with Orchestration tools like Terraform, Ansible or puppet for automated infrastructure provisioning is a plus.
Certifications: Microsoft Certified System Engineer (MCSE, Cisco Certified Network Associate (CCNA), VMware Certified Advanced Professional (VCAP), Certified Information System Security Professional (CISSP), ISA/IEC 62443 Cybersecurity Specialist certification, Global Industrial Cyber Security Professional (GICSP) is a plus.
Strong technical writing, verbal communication, interpersonal and problem-solving skills.
Strong analytical skills for effective troubleshooting and problem solving.
The expected salary range for this position based on the primary location of Oregon is $95,200 - $176,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are not available for this job posting.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Skills Required
- Bachelor's degree in Engineering, Computer Science, or equivalent experience
- 7 years systems engineer experience in automation systems
- Experience with various Operating Systems and Infrastructure Monitoring
- Advanced expertise in VMware or Nutanix
- Experience with Microsoft SQL Server
- Certifications such as Microsoft Certified System Engineer (MCSE) or CCNA
Genentech Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.
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Healthcare Strength — Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
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Retirement Support — Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
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Leave & Time Off Breadth — Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.
Genentech Insights
What We Do
Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.



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