The Role
Build agentic workflows for clinical trial automation and reliable systems for document ingestion, data transformation, validation, and auditability. Own frontend, backend, data infrastructure, and AI orchestration across the product. Collaborate with clinical teams to convert complex workflows into production software while meeting regulated healthcare standards. Work directly with founders, move quickly through ambiguous technical problems, and help establish engineering culture at an early-stage company.
Summary Generated by Built In
We are looking for a founding engineer who wants to build deeply technical AI systems in one of the most important and regulated industries in the world.
You will work directly with the founders to:
- Build agentic workflows for clinical trial automation
- Design reliable systems for document ingestion, data transformation, validation, and auditability
- Own core product surfaces across frontend, backend, data infrastructure, and AI orchestration
- Work closely with clinical teams to turn messy real-world workflows into production software
- Ship quickly while maintaining the rigor required for regulated healthcare environments
You might be a fit if you:
- Are an exceptional full-stack or backend engineer
- Care about building reliable, production-grade AI systems and can/have integrated into legacy systems in the past
- Move fast, take ownership, and like ambiguous technical problems
- Are excited by using AI to automate healthcare, clinical trials, or regulated data workflows
- Want to join at the earliest stage and help define the engineering culture
We care less about credentials and more about raw ability, taste, speed, and ownership. This is a high-agency founding role for someone who wants to build category-defining software.
Compensation: $120K - $220K salary and 0.50% - 2.00% equity.
Location: San Francisco, CA, US. Onsite.
Employment type: Full-time.
Visa sponsorship: Available.
About the interview:
1. Send us any relevant information: resume, background, GitHub.
2. 30-minute technical interview with Sanmay (CTO) and engineering.
3. Live coding session with the engineering team.
4. 30-minute culture interview.
5. Paid work trial on a realistic Astraea engineering problem, designed to evaluate how you think, build, communicate, and handle ambiguity. Can accommodate online if needed.
6. Offer.
Skills: React, TypeScript, Prompt Engineering, AI Agents, LangChain.
CompensationThe base pay range for this role is $120,000 – $220,000 per year.
Skills Required
- Exceptional full-stack or backend engineering ability
- Experience building reliable, production-grade AI systems
- Experience integrating with legacy systems
- Ability to move quickly, take ownership, and solve ambiguous technical problems
- Interest in applying AI to healthcare, clinical trials, or regulated data workflows
- React experience
- TypeScript experience
- Prompt engineering experience
- AI agents experience
- LangChain experience
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The Company
What We Do
Astraea develops an AI-native operating system for clinical development and clinical-trial automation. Its agentic software automates clinical-data workflows from protocol design through FDA submission, including document ingestion, data transformation, validation, auditability, data standards, statistical-programming outputs, and clinical-document generation. The platform is designed to help sponsors and clinical teams turn complex, messy workflows into reliable, traceable production software for regulated clinical studies.

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