Director/Sr. Director, Program Management

Reposted 2 Days Ago
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2 Locations
In-Office
110K-280K Annually
Senior level
Artificial Intelligence • Software • Biotech
The Role
Leads cross-functional drug development program management from discovery through commercialization. Responsibilities include integrated planning, critical path and timeline management, budgeting, resource forecasting, governance recommendations, risk mitigation, project team leadership, and executive communication. Requires substantial industry experience advancing programs through early- and late-stage milestones, with expertise in clinical development interdependencies across toxicology, CMC, clinical operations, and regulatory affairs.
Summary Generated by Built In

About Character Biosciences

Character Biosciences is a precision medicine company pioneering targeted therapies for ophthalmology. Our patient data platform integrates genomics with deep, longitudinal clinical and imaging data, enabling us to uncover genetic drivers of disease progression, advance novel therapeutics, and define patient stratification strategies that improve clinical success.


Our interdisciplinary team spans human genetics, clinical science, data science and engineering, and drug discovery and development. We are advancing two programs for Dry Age-related Macular Degeneration (AMD) into the clinic, with additional discovery-stage programs underway.


Founded in 2018, Character has raised capital from leading investors at the intersection of healthcare and technology, including an oversubscribed $110+ million Series B in 2025 co-led by aMoon and Luma Group, with participation from Bausch + Lomb, Innovation Endeavors, Sanofi Ventures, Catalio Capital Management, S32, KdT Ventures, and Jefferson Life Sciences. We also maintain a multi-target drug discovery collaboration with Bausch + Lomb to develop innovative precision medicines for AMD.

Role: Director/Sr. Director, Program Management

Reports to: VP, Clinical Science

Department: Clinical Development

Level: Director/Sr. Director

Location: Hybrid, Remote
The Opportunity:

The Director/Senior Director of Program Management will bridge the gap between high-level strategy and technical execution, helping to lead cross-functional teams from discovery through commercialization. This role requires a seasoned leader who thrives in the "gray area" of drug development, turning ambiguity into actionable, integrated plans.  The successful candidate demonstrates outstanding influencing and communication skills and has a solution-oriented mindset to move programs forward with a sense of urgency.


Key Responsibilities:

  • Partner with Project Team and functional heads to establish and maintain integrated program plans, identifying and managing critical paths to value-creating milestones
  •  Develop and track comprehensive program timelines and budget
  • Drive the development and implementation of comprehensive program plans, goals, budgets, and timelines. Ensure every functional area is aligned and held accountable.
  • Partnering with Finance, functional heads, and Project Team to forecast a program budget and resource needs.
  • Ensure alignment of program strategy/plan/execution with management expectations and priorities
  • Lead the development of scenarios and recommendations for decision making at various governance bodies
  • Strengthen and lead cross-functional Project Teams, fostering a culture of open collaboration, critical thinking, and a sense of urgency.  Facilitating a cross-functional meeting to identify and resolve a critical path bottleneck in a clinical trial or program.
  • Leverage deep industry knowledge to identify potential program risks early. Collaborate with the Project Team to develop robust contingency plans to ensure value-creating milestones are met.
  • Ensure accurate and timely communication -- you must be adept at framing nuanced context, capturing the rationale for decisions, and tailoring messages for diverse audiences.

Skills and Qualifications:

  • BA or BS in life sciences required; advanced degree preferred
  • Minimum of 8 years (Director) to 10 years (Sr. Director) of industry experience in drug development and program/portfolio management. Candidates must demonstrate success in advancing programs from early-phase milestones through late-stage execution, with specialized experience in Ophthalmology/retina preferred
  •  Expert-level proficiency in developing and maintaining integrated Gantt timelines (via MS Project). Must demonstrate a deep understanding of critical path methodology and the technical interdependencies between Toxicology, CMC, Clinical Ops, and Regulatory Affairs.
  •  Demonstrated experience in leading teams and cultivating effective cross-functional collaborations
  •  Ability to manage multiple competing priorities and rapidly gather, assimilate, and disseminate information on critical project components and milestones
  •  Exceptional organizational and communication skills, with a track record of effective engagement with executive management
  •  Ability to work independently and under tight deadlines

Preferred Qualifications:

  • PMP certification preferred


Compensation & Benefits
The annual pay range for this full-time position is:


Director: $205,000/yr-$250,000/yr

Senior Director: $240,000/yr-$280,000/yr

+ equity + benefits

This salary range represents the expected base compensation for this role and may vary based on factors including experience, skills, and level.
Benefits include a competitive salary, strong equity incentives, medical, dental, vision, 401(k), an accrued paid time off policy. Character is committed to recruiting, developing, and supporting colleagues from all backgrounds. We embrace diversity, equity, and inclusion as an integral part of our culture.
EEO Statement
Character Biosciences is an equal opportunity employer and is committed to building a diverse and inclusive workforce. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other legally protected status.
Work Authorization
Applicants must be authorized to work in the United States.

Skills Required

  • BA or BS degree in life sciences
  • Minimum 8 years of industry experience for Director level or 10 years for Senior Director level
  • Experience in drug development and program or portfolio management
  • Success advancing programs from early-phase milestones through late-stage execution
  • Expert proficiency developing and maintaining integrated Gantt timelines using Microsoft Project
  • Deep understanding of critical path methodology and interdependencies across Toxicology, CMC, Clinical Operations, and Regulatory Affairs
  • Experience leading teams and developing effective cross-functional collaborations
  • Ability to manage competing priorities and rapidly gather, assimilate, and communicate critical project information
  • Exceptional organizational and communication skills, including executive management engagement
  • Ability to work independently under tight deadlines
  • Authorization to work in the United States
  • Advanced degree
  • Specialized experience in ophthalmology or retina
  • PMP certification
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The Company
HQ: San Carlos, California
48 Employees
Year Founded: 2019

What We Do

Character Biosciences is a precision medicine company transforming drug development for progressive, polygenic diseases, beginning with ophthalmology. Our mission is to identify the genetic and molecular drivers of disease progression so we can develop targeted therapies for patients who urgently need them. We've built one of the most comprehensive resources in age-related eye diseases by partnering with over 150 ophthalmology clinics to integrate genetics with longitudinal clinical and imaging data. This deep phenotyping approach enables us to reclassify complex diseases like age-related macular degeneration (AMD) into genetically defined subtypes, unlocking novel therapeutic targets and optimizing patient selection for clinical trials. Character Bio’s AI-powered platform combines genomics, multi-modal data, and machine learning to discover and develop therapies that are more precise and more effective. Our lead programs, CTX114 and CTX203, are advancing toward clinical trials and are designed to slow or prevent vision loss in AMD patients. We are committed to delivering a new generation of precision medicines to treat and ultimately cure age-related blindness.

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