Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Arrowhead’s Market Access team is expanding its capabilities to support current and future product launches. The Director, Contracts & Pricing is a critical leadership role responsible for developing, optimizing, and executing pricing and contracting strategies across all stages of the Arrowhead product lifecycle. This individual will help ensure competitive positioning, maximize patient access, and enhance overall brand and enterprise value. The position reports to the Executive Director, Market Access.
This is a field-based position. Candidates must reside locally and be willing to come into Arrowhead’s Pasadena corporate office.
Responsibilities
- Support the development and execution of pricing and contracting strategies for pre-launch and in-market brands, aligned with overarching commercial goals
- Lead the creation of clear, compelling business cases to secure approval for major contracting initiatives
- Continuously monitor market dynamics, policy changes, and competitor pricing to inform recommendations and maintain competitive advantage
- Collaborate cross-functionally with Legal, Sales, Finance, and other functions to refine pricing and contracting strategies and ensure optimal product commercialization and profitability
- Support the Payer Team during key customer engagements and negotiations, representing pricing and contracting as needed
- Provide pricing and reimbursement insights to help evaluate U.S. policy and legislative developments
- Partner with Finance to support quarterly close processes, including discount forecasting, GTN analytics, and utilization by contract segment
- Drive continuous improvement and innovation in pricing and contracting processes, tools, and governance
- Ensure compliance with all federal, state, and company policies related to pricing, contracting, and market access activities
Requirements
- Bachelor’s degree in finance, economics, accounting
- 10+ years of experience in the biotech or pharmaceutical industry, including at least 5+ years in Market Access, Contracts & Pricing, or related functions.
- Extensive experience building, leading, and executing pricing and contracting strategies within the pharmaceutical or biotechnology industry
- Deep expertise in pricing and contracting analytics, including GTN forecasting and modeling
- Proven experience developing contract proposals, including financial modeling, ROI assessments, and evaluation of GTN implications, along with demonstrated negotiation strategy capability
- Strong understanding of pharmaceutical contract administration systems and reporting across payer, provider, government, specialty pharmacy, and distribution channels
- Expert knowledge of pharmacy benefits; Medicare FFS and Managed Care; Medicaid; and federal purchasing programs (e.g., VA/DoD, 340B).
- Subject-matter expertise in the Inflation Reduction Act (IRA), including financial risks and strategic opportunities for manufacturers
- Excellent verbal, written, and presentation skills, with the ability to translate complex concepts for diverse audiences
- Exceptional attention to detail, with the ability to work independently and collaboratively across cross-functional teams, external partners, and vendors
- Willingness to travel as needed to engage with customers, as required
Preferred
- Advanced degree (e.g., MBA or Master’s in a related field).
- Passion for science-driven storytelling and an interest in Arrowhead’s mission to advance RNAi-based therapeutics.
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
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Skills Required
- Bachelor's degree in finance, economics, or accounting
- 10+ years of experience in the biotech or pharmaceutical industry
- At least 5+ years in Market Access, Contracts & Pricing, or related functions
- Experience building, leading, and executing pharmaceutical or biotechnology pricing and contracting strategies
- Expertise in pricing and contracting analytics, including GTN forecasting and modeling
- Experience developing contract proposals, financial models, ROI assessments, GTN evaluations, and negotiation strategies
- Understanding of pharmaceutical contract administration systems and reporting across payer, provider, government, specialty pharmacy, and distribution channels
- Expert knowledge of pharmacy benefits, Medicare FFS and Managed Care, Medicaid, and federal purchasing programs including VA/DoD and 340B
- Subject-matter expertise in the Inflation Reduction Act, including manufacturer financial risks and strategic opportunities
- Excellent verbal, written, and presentation skills
- Ability to translate complex concepts for diverse audiences
- Exceptional attention to detail and ability to work independently and collaboratively
- Willingness to travel as needed for customer engagement
- Advanced degree such as an MBA or related master's degree
- Interest in science-driven storytelling and Arrowhead's RNAi mission
What We Do
Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, our therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Our RNAi-based therapeutics are at the leading edge of genetic-based therapy with the potential to bring life changing treatments for patients. Our Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. The TRiM platform builds on more than a decade of work on actively targeted drug delivery and offers several advantages including simplified manufacturing and reduced costs; multiple routes of administration; and potential for improved safety. Our employees are nimble, science-driven, and innovative professionals. A career at Arrowhead offers the opportunity to collaborate with top notch scientists to rapidly discover and develop RNAi-based therapeutics to add to our growing pipeline. Research and development activities are located in Madison, WI. Our R&D group includes fully-integrated capabilities for chemistry, biology, and toxicology. Madison is an exciting and sophisticated city that includes state government, the flagship campus of the University of Wisconsin, and major research organizations. Our HQ, clinical and regulatory operations are located in Pasadena, CA. Just north of Los Angeles and resting in the foothills of the San Gabriel Mountains, Pasadena is known for its natural scenic beauty, vibrant cultural and academic environment and rich architectural setting.
