Position Description:
We are seeking an experienced Contract Biostatistician to support Medical Affairs and Real‑World Evidence (RWE) activities. The role will provide statistical leadership in the design, analysis, and interpretation of RWE/observational studies, external comparator analyses, and evidence generation strategies to support post‑marketing, payer, and hypothesis generation analysis. This position requires close collaboration with cross-functional teams including Medical, HEOR, Clinical Development, and Commercial.
Responsibilities and Duties:
- Partner with medical for publication strategies, HEOR or economic modeling inputs
- Provide statistical expertise in analyses using external control and/or synthetic control, meta-analyses, and causal inference analyses, e.g. propensity score matching method
- Contribute to manuscripts, abstracts and presentations
- Collaborate with HEOR to align analyses with HTA agency expectations
- Review protocols for real world evidence studies
- Work with statistical programmers to conduct ad hoc analyses; Conduct quality review of statistical analyses
- Perform statistical programming for advanced statistical methodologies and help statistical programmers QC their programs
- Review relevant medical literature
- Write statistical analysis plans
- Develop TLF shells and review programming specs
Minimum Requirements:
Experience:
- M.S., Biostatistics or Ph.D. in Biostatistics or equivalent with at least 5 years of pharmaceutical, biotechnology, or equivalent experience.
Other:
- Prior experience working with medical affairs and commercial
- Good understanding of meta-analyses and causal inference methodologies
- Familiarity with regulatory guidance on RWE and HTA requirements
- Strong statistical reasoning and problem-solving
- Ability to communicate complex methods to non-statistical stakeholders
- High attention to data quality and methodological rigor
- Ability to work independently in a fast-paced, cross-functional environment
- Understand good clinical practice guidelines
- Good statistical programming skills using relevant statistical software
- Oncology experience preferred
Location: Syndax’s corporate office is in New York, NY.
This is a remote opportunity.
About Syndax:
Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company advancing innovative cancer therapies. Highlights of the Company’s pipeline include a menin inhibitor for R/R acute leukemia and a monoclonal antibody that blocks the CSF-1 receptor for chronic graft-versus-host disease. Fueled by our commitment to reimagining cancer care, Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment. For more information, please visit www.syndax.com/ or follow the Company on X and LinkedIn.
Syndax Pharmaceuticals is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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Skills Required
- M.S. or Ph.D. in Biostatistics or equivalent
- At least 5 years pharmaceutical, biotechnology, or equivalent experience
- Prior experience working with Medical Affairs and Commercial
- Experience with external/synthetic control analyses, meta-analyses, and causal inference (e.g., propensity score matching)
- Familiarity with regulatory guidance on RWE and HTA requirements
- Good statistical programming skills using relevant statistical software
- Ability to write statistical analysis plans and develop TLF shells
- Strong statistical reasoning, problem-solving, and high attention to data quality
- Ability to communicate complex methods to non-statistical stakeholders
- Understanding of Good Clinical Practice (GCP) guidelines
- Oncology experience
Syndax Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Syndax Pharmaceuticals and has not been reviewed or approved by Syndax Pharmaceuticals.
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Healthcare Strength — Health coverage is described as excellent, spanning medical, dental, and vision with added wellness reimbursement. Employer-funded medical and an HSA option further reinforce perceived quality and value.
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Retirement Support — The 401(k) program is portrayed as notably strong, with employer matching highlighted as a standout feature. Company disclosures position retirement support as a competitive advantage.
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Equity Value & Accessibility — Equity participation is common, with frequent new‑hire inducement stock option grants and annual bonuses as part of total rewards. Typical four‑year vesting schedules help translate equity into longer‑term value.
Syndax Pharmaceuticals Insights
What We Do
Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company developing an innovative pipeline of cancer therapies. Highlights of the Company’s pipeline include a menin inhibitor for R/R acute leukemia and a monoclonal antibody that blocks the CSF-1 receptor for chronic graft-versus-host disease. Fueled by our commitment to reimagining cancer care, Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment. Review our social media community guidelines below: https://syndax.com/social-media-community-guidelines/
