Chief of Staff

About Every Cure:    

Every Cure is an AI-driven nonprofit, biotech organization on a mission to save and improve lives by repurposing existing medicines for diseases with significant unmet need. We are working to create a world where every drug is used to treat every disease it possibly can, so that no patient suffers when an existing treatment could help them. We are filling a gap left by the current biomedical system, which doesn’t systematically pursue new uses for old drugs. Through our AI platform (named one of TIME’s Best Inventions of 2025), collaboration with healthcare professionals, and patient advocacy, Every Cure is dedicated to unlocking the full potential of existing medicines to treat every disease and every patient we possibly can. Inspired by Every Cure’s co-founders' work repurposing drugs for Castleman disease and other rare diseases, Every Cure is advancing repurposed treatments for neglected diseases and has been featured in The New Yorker,  New York Times, USA Today, Good Morning America and other news media. Led by a talented leadership team and an outstanding Board of Directors, Every Cure is supported through funding from leading philanthropic organizations like Chan Zuckerberg Initiative, TED’s Audacious Project, and ARPA-H.  

 Our approach:   

• AI-Powered Identification: We use our AI platform, which was recently named one of TIME’s Best Inventions of 2025, to analyze the world’s biomedical knowledge and identify FDA-approved drugs that can be repurposed for untreated conditions. This cutting-edge technology enables us to explore new therapeutic possibilities efficiently.   
• Open-Source Commitment: We are dedicated to making our predictive pipeline open-source, fostering collaboration and transparency within the scientific community and unlocking the potential for discovering new treatments.   
• High-Impact Focus: We prioritize drug repurposing opportunities that will relieve the most suffering and have the greatest impact possible.   
• Rigorous Validation: Promising opportunities are thoroughly validated through laboratory and clinical studies to confirm their efficacy and safety before advancing to broader application.   
• Strategic Marketing and Access: We disseminate information about effective repurposed treatments through multiple channels and are committed to ensuring that new cures are accessible to all patients. 

Every Cure is seeking a dynamic and mission-driven Chief of Staff to serve as a strategic partner to the President and Executive Team. This role sits at the heart of the organization, ensuring that Every Cure’s cross-functional priorities - spanning medical, tech, operations, and development - are aligned and executed effectively. The Chief of Staff will bridge strategic planning and operational follow-through, enabling the President and senior leadership to focus on the highest-impact initiatives. This individual will thrive in an environment that blends strategic insight, cross-functional engagement, and hands-on execution, driving clarity, alignment, and momentum across the organization. 

How you will make an impact - 

• Drive Strategic Alignment and Execution:  
  • Act as a trusted thought partner to the President, coordinating high-priority initiatives and ensuring organizational goals are aligned and advancing. 
  • Track key strategic programs and decisions, surface bottlenecks, and propose actionable recommendations to maintain momentum. 
  • Lead or support cross-functional projects and perform critical tasks that require executive oversight and collaboration. 
• Enable Executive Effectiveness: 
  • Anticipate needs and manage critical workflows, ensuring the President and executive team are prepared for and aligned on key meetings, decisions, and opportunities. 
  • Serve as a bridge between strategy and operations, ensuring decisions made at the executive level translate into execution. 
  • Track progress against goals, ensuring visibility to outcomes and next steps for the executive team.
• Lead External and Executive Communications: 
  • Craft compelling materials for the Board, funders, and scientific advisors, ensuring the President’s voice is represented across channels.
  • Support preparation for conferences, fundraising events, and strategic partnerships. 
  • Represent Every Cure in select meetings with external partners, reflecting the organization’s mission and priorities. 
  • Translate complex ideas into clear communications and action plans that drive accountability across departments.
• Shape Organizational Communication and Culture: 
  • Support and coordinate leadership meetings and all-hands gatherings, including agenda design, materials, and follow-up actions. 
  • Partner with the COO and department leads to strengthen operational clarity and accountability across teams. 
  • Develop and deliver clear, mission-aligned internal communications to keep the organization informed, inspired, and connected. 

What you bring to the team - 

• Education: 
  • Bachelor’s degree required; MBA or other advanced degree (MPA, MPH, JD, or related) preferred. 
• Experience: 
  • 7-10+ years of professional experience, ideally with exposure to executive leadership in high-performing nonprofit, startup, pharma/biotech, or management consulting environments. 
  • Demonstrated success managing cross-functional initiatives and driving strategic priorities forward. 
  • Experience supporting a C-level executive or senior leader in a Chief of Staff role is a plus. 
• Skills and Attributes: 
  • Exceptional written and verbal communication skills with the ability to craft concise, compelling narratives for diverse audiences. 
  • Strategic thinker who can synthesize complex information, identify key issues, and drive data-informed decisions. 
  • Ability to work on both high-level strategy and roll up sleeves to get things done. 
  • Highly organized and proactive, with strong project management abilities and attention to detail. 
  • High emotional intelligence, adaptability, and interpersonal effectiveness — able to build trust and navigate ambiguity. 
  • Experience representing organizations to external partners or boards preferred. 
  • Proficient in developing executive-level presentations, reports, and briefing materials. 
  • Proficiency with modern collaboration tools (e.g., Asana, Notion, Slack, Google Workspace). 

Compensations & Benefits -  

• Your paycheck: Competitive salary based on experience, starting at $150,000 annually. 
• Health and wellness: Comprehensive plans with medical, dental, and vision coverage, plus a Flexible Spending Account (FSA) for eligible healthcare expenses. 
• Future nest egg: A 403(b)-retirement plan with an employer match of 3.5% helps you save for your future. 
• Relax and recharge: Generous time off, including paid time off, sick time, and paid holidays. 
• We have you covered: Comprehensive paid leave for family and medical needs, ensuring you have the support you need during important times. 

This role is based in Philadelphia, PA, with an expectation of a minimum of 3 days per week in office.  
 
Every Cure is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We provide equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, genetics, or any other characteristic protected by federal, state, or local laws.