Be an Early Applicant
Cancer detection company enabling people at risk for high-mortality cancers to live longer, healthier lives.
The Role
Job Title: Bioinformatics Engineer I/II
FLSA: Exempt
Location: San Mateo (Preferred) , San Diego or Remote
Description
ClearNote Health is seeking a motivated and detail-oriented Bioinformatics Engineer to join our team. In this role, you will support internal research initiatives and help drive successful external collaborations through the development, maintenance, and execution of bioinformatics workflows. You will work closely with other research and development personnel in the Company to understand scientific requirements and to identify bioinformatics solutions. You will incorporate a range of existing and custom software to develop robust, scalable, and reproducible bioinformatic workflows in a timely manner. The ideal candidate should have a strong working knowledge of bioinformatics tools and pipelines, excellent organization skills, and good understanding of software engineering best-practices.
Responsibilities
Requirements
Preferred
At ClearNote Health, we are driven by our mission and guided by our values:
Compensation is based on skills, experience, and qualifications. The estimated base salary range for this position is $121,667 - $187,833. with potential variation based on depth of experience and location. This role includes stock options and generous benefits.Why ClearNote Health
ClearNote Health is a pioneering life sciences company applying next-generation epigenomic technologies to transform cancer diagnostics. Our tests are used by the National Cancer Institute and physicians around the world to detect cancer early, when it is most treatable. Founded on research from the Stanford lab of Dr. Stephen Quake and guided by world-class advisors, we are building products that provide actionable insights into human health and disease. With a passionate, experienced team and multiple commercially available tests, we are poised to make a lasting impact in precision medicine.We are based in San Diego, CA and San Mateo, CA and backed by leading investors. Join us in redefining what’s possible in early cancer detection.Our Commitment to Diversity, Equity, Inclusion, and Belonging
We believe that innovation thrives in a culture of diverse perspectives and inclusive collaboration. We are committed to building a team that reflects the patients we serve and the world we want to live in. We celebrate individuality, equity, and integrity as foundational to our mission and success.
FLSA: Exempt
Location: San Mateo (Preferred) , San Diego or Remote
Description
ClearNote Health is seeking a motivated and detail-oriented Bioinformatics Engineer to join our team. In this role, you will support internal research initiatives and help drive successful external collaborations through the development, maintenance, and execution of bioinformatics workflows. You will work closely with other research and development personnel in the Company to understand scientific requirements and to identify bioinformatics solutions. You will incorporate a range of existing and custom software to develop robust, scalable, and reproducible bioinformatic workflows in a timely manner. The ideal candidate should have a strong working knowledge of bioinformatics tools and pipelines, excellent organization skills, and good understanding of software engineering best-practices.
Responsibilities
- Develop and maintain cloud-based bioinformatics pipelines for next-generation sequencing (NGS) data in support of the research & development team
- Collaborate with the R&D team to identify and evaluate bioinformatics tools
- Collaborate with the R&D team to develop new machine learning features suitable for machine learning models trained to detect cancer and monitor treatment response
- Document requirements including expected input and output data types and example use cases
- Develop unit tests to ensure reproducible workflows
- Track development plans and progress of sprints
- Work with the rest of the engineering team to transition computational pipelines in the research environment to use in the clinical environment
- Survey current industry practices to identify opportunities for improving our code base
- Assist with servicing of customers, including the timely execution of in-house data processing and analysis pipelines and the transfer of these data to customers
Requirements
- Experience with developing scientific workflow system (e.g. Nextflow, Snakemake) for bioinformatics analysis
- Familiarity with best practices in software engineering and strong organizational skills
- Proficiency in Unix, SQL, Python and R
- Experience with working in a cloud computing environment (e.g. AWS, Azure)
- Working knowledge of molecular biology concepts and the principles of genomics technology
- Team player with excellent communication skills
- Ability to meet deadlines
- Attentive to detail with the ability to independently investigate/troubleshoot complex computational workflows
- Strong knowledge of file formats and tools commonly used in NGS bioinformatics workflows such as fastq, BAM, vcf, bed, bedtools, reference genome, annotations, bwa, WGS, samtools,
- Familiarity with containerization technology (e.g. Docker, Singularity)
- Familiarity with Git and best practices in software version control
Preferred
- Exposure to JIRA
- Experience creating visualizations for bioinformatics analysis
- Experience with differential gene expression analysis
At ClearNote Health, we are driven by our mission and guided by our values:
- Put Patients First - Focused on serving patients and their support system, we direct all our efforts toward the area of greatest impact by discovering and building with speed, excellence, and purpose.
- Redefine the Possible - We are daring, imaginative, and focused in our pursuit of the next big idea. We take calculated risks to grow our business and improve patients’ lives.
- Together We Win - We encourage and challenge each other to achieve the greatest positive impact on those we serve: our customers, patients, colleagues, and stakeholders.
Compensation is based on skills, experience, and qualifications. The estimated base salary range for this position is $121,667 - $187,833. with potential variation based on depth of experience and location. This role includes stock options and generous benefits.Why ClearNote Health
ClearNote Health is a pioneering life sciences company applying next-generation epigenomic technologies to transform cancer diagnostics. Our tests are used by the National Cancer Institute and physicians around the world to detect cancer early, when it is most treatable. Founded on research from the Stanford lab of Dr. Stephen Quake and guided by world-class advisors, we are building products that provide actionable insights into human health and disease. With a passionate, experienced team and multiple commercially available tests, we are poised to make a lasting impact in precision medicine.We are based in San Diego, CA and San Mateo, CA and backed by leading investors. Join us in redefining what’s possible in early cancer detection.Our Commitment to Diversity, Equity, Inclusion, and Belonging
We believe that innovation thrives in a culture of diverse perspectives and inclusive collaboration. We are committed to building a team that reflects the patients we serve and the world we want to live in. We celebrate individuality, equity, and integrity as foundational to our mission and success.
Similar Jobs
Get Personalized Job Insights.
Our AI-powered fit analysis compares your resume with a job listing so you know if your skills & experience align.
Success! Refresh the page to see how your skills align with this role.
The Company
What We Do
ClearNote Health – Cancer detection company enabling people at risk for high-mortality cancers to live longer, healthier lives. We focus on developing non-invasive tests to detect cancer through a standard blood draw earlier than existing methods by harnessing the power of epigenomics. We apply our proprietary epigenomic platform, combining biology and artificial intelligence, to identify DNA-based changes in biology as cancer develops. With lead programs in non-invasive early detection of pancreatic and ovarian cancers in patients at the highest risk for these diseases. Headquartered in the U.S, the company’s CLIA and CAP-accredited laboratory is located in San Diego, Calif., with additional presence in the San Francisco Bay Area and internationally. #biotechnology #epigenomics #oncology #cancerresearch #cancer
