About Artiva:
Artiva is clinical-stage, publicly-traded biotechnology company focused on developing natural killer (NK) cell-based therapies for patients suffering from devastating autoimmune diseases and cancers. Artiva’s lead program, AlloNK®, is an allogeneic, off-the-shelf, non-genetically modified NK cell therapy candidate designed to enhance the antibody-dependent cellular cytotoxicity effect of monoclonal antibodies to drive B-cell depletion. AlloNK is delivered in the outpatient setting with no required hospitalization.
AlloNK is currently being evaluated in three ongoing clinical trials for the treatment of B-cell driven autoimmune diseases. This includes two company-sponsored trials, one in systemic lupus erythematosus for patients with or without lupus nephritis, and a basket trial across autoimmune diseases (Rheumatoid Arthritis, Systemic Sclerosis, Idiopathic Inflammatory Myopathies and Sjögren’s Disease), as well as an investigator-initiated basket trial in B-cell driven autoimmune diseases. Artiva’s pipeline also includes CAR-NK candidates targeting both solid and hematologic cancers.
Artiva was founded in 2019 as a spin out of GC Cell, formerly GC Lab Cell Corporation, a leading healthcare company in the Republic of Korea, pursuant to a strategic partnership granting Artiva exclusive worldwide rights (excluding Asia, Australia and New Zealand) to GC Cell’s NK cell manufacturing technology and programs. Artiva is headquartered in San Diego, California.
For more information, visit www.artivabio.com.
Job Summary:
Artiva Biotherapeutics is seeking a skilled and highly motivated Associate Scientist who will be responsible for translational assay development and clinical sample processing, testing, and data analysis. This position will be responsible for establishing protocols, qualifying assays, and conducting in vitro testing to access pharmacokinetic and pharmacodynamic response to NK cell therapies, including immune cell activation and cytokine profiling. The successful candidate will contribute to biomarker development and analysis to support ongoing clinical trials in oncology and autoimmunity. The candidate must have experience with processing human peripheral blood and flow cytometry analysis. This position is temporary.
Key Responsibilities
- Collaborate with Translational teams to support clinical biospecimen receipt, processing and characterization.
- Conduct cell-based assays such as immunophenotyping, cytotoxicity, cell proliferation, serum cytokine/chemokine analysis (MSD platform a plus).
- Processing human blood samples for biomarker analysis.
- Assures compliance with protocols, SOPs and work practices.
- Complies with standard laboratory procedures and company policies, including notebook documentation and safety protocols.
Requirements
- MS degree with 5+ years or BS with 8+ years of experience within the biotechnology or pharmaceutical industry.
- Experience with multi-parameter flow cytometry (sample acquisition)
- Demonstrate basic immunology training with strong cellular immunology and cell culture technical skills, including experience with PBMC isolation and cryopreservation.
- Ability to work both independently and as part of a team, attention to detail and data quality and demonstrating excellent communication and interpersonal skills is required.
- Excellent computer skills with experience using flow cytometry analysis software, including FlowJo, Graphpad PRISM and Microsoft office.
- Flexibility to work on Saturdays.
Why you should apply:
We have a fantastic team and philosophy! We are passionate – We deeply care about our team, our science, and improving the lives of autoimmune and cancer patients. We are tenacious – we are laser-focused on our mission and undeterred in our commitment to make cell therapies broadly accessible to patients with autoimmune disease and cancer. We are innovative - pushing into new frontiers for patient benefit. We are transparent - believers in flat, accessible, and open communication paths. We are inclusive – committed to the diversity of our team and ensuring that all voices are heard.
Base Salary: $110,000 - $115,000. Exact compensation may vary based on skills and experience.
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What We Do
At Artiva, our mission is to deliver to cancer patients highly effective cellular immunotherapies that are also safe and immediately accessible. Towards this end, Artiva is advancing a pipeline of off-the-shelf, allogeneic NK cell therapies, including CAR-NK cell therapies, that leverage the company’s unique manufacturing and engineering capabilities. Artiva is headquartered in San Diego.
