Associate Principal/Senior Manager / Associate Director – Platform Engineering, Cloud & DevOps
Position Overview
We are seeking a seasoned Platform Engineering leader with a strong foundation in Cloud Engineering, DevOps, Infrastructure Automation, and Site Reliability Engineering to help shape and advance Illumina's global engineering platforms.
This role is ideal for an experienced Engineering Manager, Senior Technical Lead, or senior engineering professional who combines deep technical expertise with proven experience leading high-performing engineering teams, driving enterprise-scale transformation, and influencing technology strategy.
The successful candidate will provide technical leadership across globally distributed teams, drive platform modernization and engineering excellence, and partner with cross-functional stakeholders to deliver secure, scalable, resilient, and highly automated cloud platforms.
The role requires a strategic mindset, strong architectural judgment, and the ability to translate engineering investments into measurable improvements in platform reliability, developer productivity, operational efficiency, and business value.
Responsibilities – Engineering Leadership & Strategy
- Engineering Leadership: Provide technical leadership, mentorship, and strategic direction to Platform Engineering, Cloud Engineering, and DevOps teams. Foster a culture of engineering excellence, accountability, innovation, and continuous improvement.
- Technology Strategy & Roadmap: Partner with global engineering leadership to define and execute platform engineering strategies, technical roadmaps, architectural standards, and modernization initiatives aligned with enterprise objectives.
- Enterprise Platform Ownership: Lead the architecture, engineering, and evolution of enterprise-scale cloud platforms, with accountability for scalability, security, reliability, operational efficiency, and long-term sustainability.
- Cross-Functional Leadership: Collaborate with senior technology leaders, architects, cybersecurity, infrastructure, and application engineering teams to influence technical decisions, resolve complex challenges, and drive cross-functional initiatives across geographically distributed teams.
- Cloud & DevOps Transformation: Champion the adoption of cloud-native architectures, Infrastructure as Code, DevSecOps, CI/CD automation, and self-service platform engineering capabilities to improve engineering productivity and accelerate software delivery.
- Operational Excellence & SRE: Establish and continuously improve engineering practices around observability, platform resilience, incident management, root cause analysis, performance optimization, and service reliability.
- Talent Development & Technical Mentorship: Guide and mentor senior engineers and technical leads, strengthen engineering capabilities, promote knowledge sharing, and support the development of future technical leaders.
- Innovation & Business Outcomes: Evaluate emerging technologies, including AI-driven operations and intelligent automation, to modernize enterprise platforms, reduce operational toil, optimize cloud costs, and deliver measurable improvements in reliability, engineering efficiency, and service delivery.
Experience & Qualifications
- 15+ years of progressive experience in Platform Engineering, Cloud Engineering, DevOps, Infrastructure Engineering, Site Reliability Engineering, or related technology domains, consistent with the applicable education and equivalent-experience requirements.
- Demonstrated experience in technical leadership, engineering management, or senior technical lead roles, with responsibility for guiding engineering teams, driving architectural decisions, and delivering large-scale technology initiatives.
- Proven ability to lead and influence high-performing engineering teams, including mentoring senior engineers, providing technical direction, and driving engineering excellence across multiple workstreams.
- Demonstrated experience defining and executing technology strategies, engineering roadmaps, and platform modernization initiatives within complex enterprise environments.
- Strong understanding of enterprise-scale public cloud architecture, preferably AWS, including cloud networking, security, automation, containerization, Kubernetes, and Infrastructure as Code.
- Experience leading or driving DevOps, DevSecOps, CI/CD, platform automation, and cloud transformation initiatives with measurable improvements in reliability, scalability, operational efficiency, or engineering productivity.
- Strong architectural judgment and ability to evaluate complex technical trade-offs, influence engineering decisions, and guide teams through design and implementation.
- Proven ability to collaborate with senior technology stakeholders and globally distributed engineering teams, communicate technical strategies effectively, and influence decisions without direct organizational authority.
- Experience establishing engineering standards, operational excellence practices, technical governance, and continuous improvement frameworks across enterprise platforms.
- Experience driving technology adoption and engineering innovation, including cloud-native platforms, self-service infrastructure, observability, and automation.
Preferred Qualifications
- Previous experience as an Engineering Manager, Senior Engineering Manager, Platform Engineering Lead, DevOps Engineering Manager, Cloud Engineering Manager, Associate Director, or equivalent technical leadership role.
- Experience leading multidisciplinary engineering teams across Platform Engineering, Cloud, DevOps, Infrastructure, or SRE functions.
- Familiarity with cloud financial management (FinOps), platform security, AI-assisted operations, and emerging engineering automation technologies.
- Experience working in a global enterprise environment, particularly within life sciences, healthcare, or other highly regulated industries, is a plus.
We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.
Skills Required
- Minimum 15 years of related experience with a bachelor's degree, or 12 years with a master's degree, or equivalent experience
- Expertise administering, configuring, optimizing, and monitoring Linux and related distributions at scale
- Experience with SaaS infrastructure at scale
- Experience with AWS or other public cloud deployment and support
- Advanced knowledge of virtual network design and Internet protocols
- Ability to troubleshoot complex network infrastructure
- Programming or scripting skills in Bash, Python, Go, SQL, NoSQL, log query languages, or related technologies
- Expertise in scaling, availability, security, and monitoring
- Experience with large-scale data systems, relational databases, ELK, or MongoDB
- Experience with virtual compute systems, Kubernetes, Docker containers, or Hadoop
- Experience with messaging systems such as RabbitMQ, Kafka, or Service Bus
- Experience with network infrastructure and cybersecurity controls
- Experience implementing infrastructure as code using Terraform, Ansible, CloudFormation, or similar tools
- Technical certifications in public cloud services or security-related domains
- Ability to learn new technologies quickly and perform deep technical investigations
- Ability to communicate with internal customers and collaborate cross-functionally
Illumina Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Illumina and has not been reviewed or approved by Illumina.
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Healthcare Strength — Health coverage includes comprehensive medical (HMO/PPO), dental, vision, mental health, life, and disability insurance with options such as FSAs/HSAs and wellness resources. Offerings are described as robust across regions with customization in certain locations.
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Leave & Time Off Breadth — Time-off programs include flexible schedules and remote work, PTO or flexible time off, paid holidays and sick leave, and volunteer time. Company-wide shutdowns during summer and winter add additional paid time away.
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Parental & Family Support — Family-focused programs include fertility assistance, adoption assistance, and reproductive health support alongside family medical leave. Paid parental leave is provided, with specifics varying by country and employment status.
Illumina Insights
What We Do
Illumina is an innovative technology and revolutionary assays aiming the analyze genetic variation and function.

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