About Us
iota Biosciences, a wholly owned subsidiary of Astellas Pharma US, is advancing a new class of bioelectronic medicines through the development of fully implantable Class III medical devices. Our proprietary technologies open therapeutic and diagnostic possibilities not previously accessible to clinicians.
Together with Astellas, we are committed to patient-centric design, scientific and engineering excellence, and cross-functional teamwork. These principles guide us in bringing transformative, first-of-its-kind technologies into the clinic and closer to patients.
About the Role
iota is looking for a hands-on finance leader who thrives in early-stage environments and wants to build. This role is ideal for a senior staff accountant or early FP&A professional who has a strong foundation in accounting but also wants to step into broader ownership of budgeting, burn-rate tracking, process creation, and day-to-day financial operations.
You will be responsible for the day-to-day finance function, working closely with our fractional CFO and leadership team to establish the systems, processes, and financial discipline needed to scale a new venture. This is a highly visible, cross-functional role with a real opportunity to shape how the company grows.
What You’ll Do
Financial Operations & Accounting
Oversee day-to-day accounting operations, including AP, month-end close, reconciliations, and journal entries.
Partner with external accounting and PEO teams to ensure accurate payroll, benefits, payroll tax processes and day-to-day accounting.
Maintain the general ledger and ensure compliance with US GAAP.
Support monthly, quarterly, and annual financial statements; prepare flux analysis; prepare schedules for audits and reviews.
Manage the company’s use tax compliance, including preparing, documenting, and filing periodic returns. Work with the tax firm to support additional filings such as business property tax and franchise tax.
Budgeting, Forecasting & Reporting
Build and manage budgets in partnership with department leads and the fractional CFO; provide real-time visibility into actuals vs. budget.
Track and forecast burn rate, headcount costs, vendor spend, and runway—proactively flagging risks and insights.
Develop dashboards and reporting that help leadership make informed decisions.
Systems, Processes & Internal Controls
Implement early financial systems, tools, and scalable processes (e.g., expense management, purchasing flows, cost tracking).
Create simple but effective internal controls appropriate for an early-stage company.
Lead vendor onboarding and contract tracking; partner with legal and operations teams as needed.
Creating and updating expense and travel policies and maintaining internal compliance.
Cross-Functional Support
Work closely with R&D, Clinical, Operations, and HR to align finance with business needs.
Help model scenarios for hiring, lab expansion, grants, capital planning, and investment decisions.
Support board reporting, investor updates, and fundraising preparation.
Who You Are
5–8 years of accounting experience (startup or high-growth environment strongly preferred).
Strong understanding of US GAAP with hands-on accounting capability—but also excited to expand into FP&A.
Scrappy, detail-oriented, and comfortable wearing many hats—this role spans accounting, operations, and finance strategy.
Someone who wants to own the finance function day-to-day, not just support it.
Comfortable with ambiguity, building processes from scratch, and creating structure where none exists.
Experience with finance systems; QuickBooks and Ramp a plus.
Why This Role Is Exciting
You’ll be joining at the formation stage of a new, well-funded company—your work will directly influence how the company grows.
You’ll partner closely with experienced leaders (CEO, COO, fractional CFO) and gain exposure to strategic decision-making.
You’ll build foundational systems from the ground up, not inherit legacy processes.
Clear growth path into Finance Manager or Controller as the company scales.
Top Skills
What We Do
iota Biosciences, a wholly-owned subsidiary of Astellas Pharma US, is a medical device company working to develop pioneering bioelectronics to advance the treatment and management of disease. Founded in 2017 to build on the award-winning ultrasound technology invented at the University of California, Berkeley, iota Biosciences is committed to improving human life and bringing our groundbreaking approaches to the patients who need them.
Using innovative science and technology, our mission is to create and develop state-of-the-art diagnostic and therapeutic bioelectronic devices that are safe and effective. We are working to transform the way doctors manage and treat disease to make a life-changing difference for patients.
We are proud and privileged to be powered by Astellas, a leading global pharmaceutical company that brings experience, reach and rigor. With a shared transformational vision and a commitment to the realization of greater value to patients, together we are creating innovative technologies that will change patients’ lives.
