Amigo partners with healthcare organizations to deploy robust AI infrastructure that directly serves patients and providers. Our agents handle clinical workflows and patient engagement across the entire journey: pre-visit intake, care navigation, post-visit care plans, patient monitoring, and more.
We're fresh off our Series A backed by Tier 1 investors like Madrona, General Catalyst, and Optum Ventures. Our work is validated with leading academic medical institutions. Our agents have reached 3M+ patient encounters and are on track to 10x this year.
About this role
Applied AI is how we turn a customer's hardest clinical workflow into production AI that actually ships. As an Applied AI Engineer, you own the technical delivery of real deployments end to end. You design the agents, build them, and are on the hook for whether they work in the field. The team is small and dense, and you get a lot of surface area early.
We hire Applied AI Engineers across every level, from new grads to deeply experienced engineers, and we work out level together once we've met you. What matters is not years on a resume but whether you can take an ambiguous problem and turn it into something reliable that patients and clinicians depend on.
What you might work on
Designing and building an AI agent for a specific clinical workflow, from first prototype to production
Deciding what an agent should and should not handle, and where it hands off to a human
Building the evaluations that decide whether an agent is safe to ship, and catching failure modes before patients do
Writing the integrations that let agents work inside a customer's existing systems
Debugging why a live conversation went wrong and fixing it across the whole stack
Finding the patterns that repeat across customers and turning them into something reusable
You may be a fit if
You've built real software that other people relied on, and you care whether it actually works, not just whether it shipped
You're comfortable with LLMs and agents, or you'll get comfortable fast
You take ownership. When something is broken you fix it, and you say so early when something is more than you can carry
You have good judgment about tradeoffs, and you'd rather get the direction right than move fast in the wrong one
You're low ego, direct, and hold yourself to a high bar
You can work on site in San Francisco
This role spans new grads through senior and staff engineers. Strong early-career people are welcome, and so are people who have done this work for a long time.
Nice to have
Experience in a regulated or high-reliability domain (healthcare, finance, legal)
Background with evaluation, simulation, or synthetic data
Experience working directly with customers or domain experts
Python depth and experience building reliable systems on top of external APIs
Benefits (available to Full-Time Employees)Health & Wellness
Comprehensive health, dental, and vision insurance
Daily catered lunch and dinner
Mental health support and wellness coaching
Flexible wellness stipend for fitness, therapy, or personal growth
Annual learning budget for courses, books, or conferences
Conference attendance budget for professional development
Annual team offsite
Academic collaboration opportunities
Unlimited PTO
Patients Win, We Win
If patients aren't getting better care, we haven't earned the right to scale. Every internal decision gets pressure-tested: does this make patients' lives better? If we can't draw the line, we question why we're doing it.
High Standards, High Care
We hold a high bar for the team because patients are counting on us to get this right. But high standards only work with genuine investment in each other. You can take risks, admit mistakes, and challenge ideas—not despite our standards, but because of them.
Thoughtful Urgency
We move fast by default, but speed without judgment is recklessness. The discipline is knowing which decisions are reversible vs. not. In healthcare AI, the companies that win will be fast everywhere they can be and careful everywhere they must be. We build the muscle to do both.
Intensely Measured
We instrument patient outcomes, provider ROI, system performance, and clinical accuracy. But data without action is surveillance. Every metric should have an owner, a threshold, and a response plan. If we're measuring something but never acting on it, we stop measuring it.
Low ego: Politics and territory don't interest you. The best ideas win, regardless of who has them.
Direct: You say the hard thing, challenge ideas openly, and commit fully once decided.
High agency: You thrive on trust rather than instruction. When you see something is broken, you fix it. You don’t file tickets and wait for someone else.
Bar of excellence: You hold yourself to a bar most people wouldn't, and you want teammates who do the same.
Skeptical: You push back on rules that don’t make sense and question assumptions that haven’t earned their place.
Skills Required
- Experience building production software relied on by others (ownership of reliability)
- Comfortable with large language models and agent-based systems
- Ability to work on site in San Francisco
- Experience in regulated or high-reliability domains (healthcare, finance, legal)
- Background with evaluation, simulation, or synthetic data
- Experience working directly with customers or domain experts
- Python depth and experience building reliable systems on top of external APIs
What We Do
Amigo AI builds trust and safety infrastructure for clinical agents—ensuring AI systems in healthcare provide quantified confidence when mistakes aren't an option. Our platform combines advanced simulation, verification, and recursive optimization to enable healthcare organizations to deploy AI with statistical guarantees about its behavior. We solve the fundamental challenge of reliable AI in critical domains through deterministic verification for clinical protocols and continuous drift detection for real-world performance. Our systems provide complete transparency—every AI decision is traceable and auditable, with quantified confidence intervals rather than black box predictions. Founded by technologists from Google, Meta AI, Databricks, Coda, and Plaid, we've built systems that let organizations make informed risk decisions about AI deployment in healthcare. Our interdisciplinary approach draws from computer science, economics, physics, and mathematics to tackle human-centric optimization problems where people and populations are at the center of every solution. We're actively working with healthcare organizations across digital health, cancer care, cardiac care, and personalized medicine to deploy AI systems that continuously learn and adapt from real-world feedback while maintaining verified safety boundaries. Our technology amplifies human expertise rather than replacing it, empowering domain experts to achieve outcomes neither could accomplish alone.
Why Work With Us
We build AI healthcare systems where 99% isn't good enough. Rapid growth—promotions in 3 months. Freedom to work your way: art museums or late nights. Tackle recursive optimization problems that ship to production. Your work directly impacts critical healthcare decisions. Diverse team from Google, Meta AI, Databricks solving problems that matter.
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