SUMMARY/JOB PURPOSE
The Engineer II - AI and Agentic is responsible for designing, building, and deploying production-grade agentic applications that automate multi-step IT and business workflows across Exelixis. This role delivers spec-driven, testable, and secure AI solutions, contributes to platform patterns and reusable components, while advancing the engineering standards.
ESSENTIAL DUTIES/RESPONSIBILITIES
- Design and deliver end-to-end agentic applications and multi-agent workflows that automate IT and business processes.
- Convert prototypes into hardened, production-ready services with clear specifications, modular design, robust error handling, and comprehensive test coverage.
- Integrate LLMs, prompts, tools, APIs, and enterprise data sources (e.g., Bedrock, Databricks Mosaic AI, MCP servers) into reliable use cases.
- Implement CI/CD pipelines, automated evaluation harnesses, observability, and artifact versioning for AI/agent workloads.
- Author architecture notes, runbooks, SOPs, and technical documentation to support adoption, operability, and maintainability.
- Lead prompt/spec reviews, code reviews, threat modeling exercises, and release-readiness gates.
- Apply and evangelize secure-by-design and responsible AI principles, including data governance, privacy, and safe prompting aligned to organizational policy
- Contribute reusable components, patterns, and internal libraries to the platform
- Partner with product managers, security, and platform teams to translate business needs into scalable technical solutions
- Performs other duties as assigned
- Complies with all policies and standards
SUPERVISORY RESPONSIBILITIES
- No supervisory responsibilities
EDUCATION/EXPERIENCE/KNOWLEDGE/SKILLS & ABILITIES
Education
- Bachelor's degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 5 years of related experience; or
- Master’s degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 3 year or related experience; or
- Equivalent combination of education and experience.
Experience
- 2 - 4 years of relevant experience in AI application, data science, automation, or related technical work, including hands-on experience building or contributing to LLM-enabled applications, agentic workflows, API integrations,
Knowledge, Skills and Abilities
Required:
- Intermediate to Advanced proficiency in Python and/or JavaScript/TypeScript, including modular design, testing, and packaging.
- Intermediate proficiency with agent frameworks and agentic patterns: tool use, planning/execution loops, guardrails, evaluation, and prompt/version management.
- Intermediate proficiency building and consuming REST APIs, and integrating enterprise systems with OAuth/JWT, secrets management, and secure data handling.
- Intermediate proficiency with CI/CD, automated testing (unit/integration), linting, and observability for AI applications.
- Intermediate understanding of security best practices, architecture design principles, and responsible AI/data governance.
- Intermediate communication skills, written and verbal, and demonstrated ability to collaborate with cross-functional stakeholders and mentor junior engineers.
- Intermediate experience with cloud AI platforms — preferably AWS Cloud, AWS Bedrock, and Databricks Mosaic AI — and vector stores or retrieval-augmented generation (RAG) patterns.
- Intermediate knowledge of AI-native engineering using Claude Code, Codex, GitHub Copilot, or equivalent coding agents.
Preferred:
- Experience delivering evaluation frameworks, red-teaming, or LLM observability tooling.
Travel Requirements
- No travel is required for this position.
#LI-EZ1
Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $152,000 - $215,000 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors.In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.If you have a disability and need an accommodation in relation to the recruiting process, please email us at: [email protected].
WORKING CONDITIONS:
Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.
DISCLAIMER:
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.
We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.
Skills Required
- Bachelor's degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or related field and 5 years experience; OR Master's degree and 3 years experience; OR equivalent combination of education and experience.
- 2-4 years of relevant experience building or contributing to LLM-enabled applications, agentic workflows, and API integrations.
- Intermediate to advanced proficiency in Python and/or JavaScript/TypeScript, including modular design, testing, and packaging.
- Intermediate proficiency with agent frameworks and agentic patterns (tool use, planning/execution loops, guardrails, evaluation, prompt/version management).
- Intermediate proficiency building and consuming REST APIs and integrating enterprise systems with OAuth/JWT, secrets management, and secure data handling.
- Intermediate proficiency with CI/CD, automated testing (unit and integration), linting, and observability for AI applications.
- Intermediate understanding of security best practices, architecture design principles, and responsible AI/data governance.
- Intermediate experience with cloud AI platforms, preferably AWS Cloud, AWS Bedrock, and Databricks Mosaic AI, and with vector stores or RAG patterns.
- Intermediate knowledge of AI-native engineering using Claude Code, Codex, GitHub Copilot, or equivalent coding agents.
- Strong written and verbal communication skills with demonstrated ability to collaborate cross-functionally and mentor junior engineers.
- Experience delivering evaluation frameworks, red-teaming, or LLM observability tooling.
Exelixis Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Exelixis and has not been reviewed or approved by Exelixis.
-
Retirement Support — Retirement plans are highlighted as a strength, featuring a 401(k) with generous company contributions and immediate vesting. This emphasis signals strong long‑term financial support within the total rewards package.
-
Healthcare Strength — Healthcare coverage is positioned as comprehensive, with multiple medical plan options (HDHP with HSA, EPO, and Kaiser HMO in CA) and employer HSA contributions in 2026. Posted plan documents and contribution details indicate structured support for managing care and costs.
-
Parental & Family Support — Family support is robust, including fully paid parental leave, caregiver leave, and expanded fertility benefits. Additional elements such as grandparent leave and backup care broaden assistance across life stages.
Exelixis Insights
What We Do
Every Exelixis employee is united in an ambitious cause: to launch innovative medicines that give patients and their families hope for the future. In this pursuit, we know our employees are our most valuable asset. After operating in the challenging biotech sector for more than 25 years, we have a proven track record of resiliency in the face of adversity. The success of our lead product has provided a solid commercial foundation allowing us to reinvigorate our research efforts, and grow our team in areas such as Drug Discovery, Clinical Development and Commercial. As we expand our global partnerships and further reinvest in R&D to help us discover the next breakthrough for difficult-to-treat cancers, we’re seeking to add talented, dedicated employees to power our mission. Cancer is our cause. Make it yours, too. Please see our Community Guidelines: bit.ly/2XXw9w3 For more information about Exelixis, please visit www.exelixis.com, follow @ExelixisInc on Twitter or like Exelixis, Inc. on Facebook.







